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Patrick Schwientek
Researcher at Joint Genome Institute
Publications - 27
Citations - 3839
Patrick Schwientek is an academic researcher from Joint Genome Institute. The author has contributed to research in topics: Genome & Metagenomics. The author has an hindex of 20, co-authored 27 publications receiving 3304 citations. Previous affiliations of Patrick Schwientek include Bayer & Ruhr University Bochum.
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Journal ArticleDOI
Insights into the phylogeny and coding potential of microbial dark matter
Christian Rinke,Patrick Schwientek,Alexander Sczyrba,Alexander Sczyrba,Natalia Ivanova,Iain Anderson,Jan Fang Cheng,Aaron E. Darling,Aaron E. Darling,Stephanie Malfatti,Brandon K. Swan,Esther A. Gies,Jeremy A. Dodsworth,Brian P. Hedlund,Georgios Tsiamis,Stefan M. Sievert,Wen Tso Liu,Jonathan A. Eisen,Steven J. Hallam,Nikos C. Kyrpides,Ramunas Stepanauskas,Edward M. Rubin,Philip Hugenholtz,Tanja Woyke +23 more
TL;DR: This study applies single-cell genomics to target and sequence 201 archaeal and bacterial cells from nine diverse habitats belonging to 29 major mostly uncharted branches of the tree of life and provides a systematic step towards a better understanding of biological evolution on the authors' planet.
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Prevalent genome streamlining and latitudinal divergence of planktonic bacteria in the surface ocean
Brandon K. Swan,Ben Tupper,Alexander Sczyrba,Federico M. Lauro,Manuel Martinez-Garcia,José M. González,Haiwei Luo,Jody J. Wright,Zachary C. Landry,Niels W. Hanson,Brian P. Thompson,Nicole J. Poulton,Patrick Schwientek,Silvia G. Acinas,Stephen J. Giovannoni,Mary Ann Moran,Steven J. Hallam,Ricardo Cavicchioli,Tanja Woyke,Ramunas Stepanauskas +19 more
TL;DR: It is shown that the global distribution of surface ocean bacterioplankton correlates with temperature and latitude and is not limited by dispersal at the time scales required for nucleotide substitution to exceed the current operational definition of bacterial species.
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UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota
James H. Campbell,Patrick O'Donoghue,Alisha G. Campbell,Patrick Schwientek,Alexander Sczyrba,Tanja Woyke,Dieter Söll,Mircea Podar,Mircea Podar +8 more
TL;DR: Comparative genomic analysis with Human Microbiome Project data revealed that the human body harbors a striking diversity of SR1 bacteria, which is a surprising finding because SR1 is most closely related to bacteria that live in anoxic and thermal environments.
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Genome-wide selective sweeps and gene-specific sweeps in natural bacterial populations
Matthew L. Bendall,Sarah L. R. Stevens,Leong-Keat Chan,Stephanie Malfatti,Patrick Schwientek,Julien Tremblay,Wendy Schackwitz,Joel Martin,Amrita Pati,Brian Bushnell,Jeff Froula,Dongwan D. Kang,Susannah G. Tringe,Stefan Bertilsson,Mary Ann Moran,Ashley Shade,Ryan J. Newton,Katherine D. McMahon,Rex R. Malmstrom +18 more
TL;DR: Examination of changes in single-nucleotide polymorphism (SNP) frequencies and patterns of gene gain and loss in 30 bacterial populations revealed substantial genetic heterogeneity within these populations, although the degree of heterogeneity varied by >1000-fold among populations.
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Phylogeny and physiology of candidate phylum 'Atribacteria' (OP9/JS1) inferred from cultivation-independent genomics
Masaru K. Nobu,Jeremy A. Dodsworth,Jeremy A. Dodsworth,Senthil K. Murugapiran,Christian Rinke,Christian Rinke,Esther A. Gies,Gordon Webster,Patrick Schwientek,Peter Kille,R. John Parkes,Henrik Sass,Bo Barker Jørgensen,Andrew J. Weightman,Wen Tso Liu,Steven J. Hallam,George Tsiamis,Tanja Woyke,Brian P. Hedlund +18 more
TL;DR: C cultivation-independent genomic approaches were used to provide a first comprehensive view of the phylogeny, conserved genomic features and metabolic potential of members of this ubiquitous candidate phylum, and confirmed the monophyly of the ‘Atribacteria’ inclusive of OP9 and JS1.