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Patryk Kaczor

Bio: Patryk Kaczor is an academic researcher from Nicolaus Copernicus University in Toruń. The author has contributed to research in topics: Beta (finance) & Surgery. The author has an hindex of 2, co-authored 6 publications receiving 10 citations.

Papers
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Journal ArticleDOI
TL;DR: Effects of use of schisandrins are very promising, however, there is still not enough of good evidences to use these substances without any doubts.

8 citations

Journal ArticleDOI
15 Oct 2019
TL;DR: The gold standard in diagnostics is the method of direct immunofluorescence, through which viral antigens are detected – mainly in the saliva of a patient – and rabies treatment is an experimental form of therapy according to the Milwaukee protocol.
Abstract: Abstract The genus Lyssavirus spp. currently includes 14 species that are responsible for causing rabies, rabies-like and rabies-related diseases. The first symptoms of infection are similar to a cold and mainly include fever, headache and general fatigue. Then comes brain dysfunction and acute neurological symptoms, and ultimately – in most cases – death. Lyssaviruses are spread mainly through direct contact with the carrier that contains the viral reservoir. The gold standard in diagnostics is the method of direct immunofluorescence, through which viral antigens are detected – mainly in the saliva of a patient. Currently, rabies treatment is an experimental form of therapy according to the Milwaukee protocol. 1. Introduction. 2. Systematics. 2.1. Lagos bat virus. 2.2. Mokola virus. 2.3 Duvenhage virus. 2.4. European bat 1 lyssavirus. 2.5. European bat 2 lyssavirus. 2.6. Australian bat lyssavirus. 3. Characteristics. 3.1. Molecular structure. 3.2. Genome and gene expression. 3.3. Life cycle. 4. Pathogenicity. 4.1. Pathogenesis. 4.2. Rabies symptoms. 5. Prevention, prophylaxis, diagnostics, treatment. 5.1. Vaccinations. 5.2. Postexposure prophylaxis. 5.3. Diagnostics. 5.4. Experimental treatment. 6. Summary

2 citations

Journal ArticleDOI
TL;DR: After achieving the maximum dose of the drug later than recommended in the Recommendation of the Polish Haemangioma and Vascular Malformations Group criteria, there was no need for longer therapy, while the effectiveness of the treatment remained unchanged.
Abstract: Introduction Haemangioma, one of the most common benign neoplasms of early childhood, is a significant clinical problem due to cosmetic reasons but also because of possible health complications. Aim Presentation of the method and results of treatment of infantile haemangiomas (IHs) using propranolol in a maximum dose of 3 mg/kg/day. Material and methods In 2013 to 2018 there were 108 patients with IHs multidisciplinary diagnosed and treated. 77 of them were girls and 31 were boys; all were between the ages of 2 and 21 months (mean: 6.87 months). Lesions were most often located in the head region (n = 73). The main imaging study assessing the arteriovenous flow was USG, which was used to assess the size of haemangioma and its regression or progression. Also, coagulation parameters were analysed using laboratory tests. Results Reduction of lesions occurred in 103 of 108 patients, which results in a percentage score above 95. In 19 patients, after completion of treatment, there were abnormalities of coagulation in laboratory tests whereas before the treatment, these abnormalities occurred in 82 patients. The average duration of treatment was longer than 12 months and the maximum dose of propranolol of 3 mg/kg/day was achieved after 3 to 5 months of treatment. Side effects occurred totally in 19 patients, with night anxiety and nightmares being the most common. Conclusions After achieving the maximum dose of the drug later than recommended in the Recommendation of the Polish Haemangioma and Vascular Malformations Group criteria, there was no need for longer therapy, while the effectiveness of the treatment remained unchanged. Side effects that occurred were not life-threatening or detrimental to the health of patients.

2 citations

Journal ArticleDOI
TL;DR: Genistein is a potential nutrient for physically active people and shows myoprotective effect, preventing muscle atrophy and damage, and also affects the growth of muscle mass.

2 citations

DOI
31 May 2019
TL;DR: New Delhi, an enzyme belonging to the Metallo-beta-lactamases and Carbapenemases group, is most commonly found in Klebsiella pneumoniae and Escherichia coli and determines these bacteria resistance to the majority of known antibiotics.
Abstract: New Delhi, an enzyme belonging to the Metallo-beta-lactamases and Carbapenemases group, is most commonly found in Klebsiella pneumoniae and Escherichia coli. It determines these bacteria resistance to the majority of known antibiotics. NDM-1 was discovered in 2008 in a man treated in New Delhi for E. coli infection. Since the first appearance, 17 subtypes of this enzyme have been discovered. Its occurrence has been reported in Europe (Great Britain, France, Belgium where even a national alert has been

1 citations


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Journal ArticleDOI
TL;DR: Infantile hemangiomas (IH) affect up to 10% of infants and a rapid proliferative phase is followed by slow spontaneous involution.
Abstract: Infantile hemangiomas (IH) affect up to 10% of infants. A rapid proliferative phase is followed by slow spontaneous involution. Approximately 12% of IH

205 citations

Journal Article
TL;DR: Most hemangiomas will regress spontaneously, but treatment as early as possible with the appropriate modality can provide better results, especially with the new therapeutic modalities such promising class of beta blockers.
Abstract: 1024x768 Hemangiomas are benign neoplasms composed of proliverative and hyperplastic vascular endothelium with characteristic rapid growth of initial phase followed by involution phase or regression . Hemangiomas are the most common benign vascular tumor in the naonatus . The pathogenesis of hemangiomas still can not be explained with certainty although there is some suspicion about the cause. Clinical symptoms and diagnosis of hemangioma can be seen by the growth phase of hemangioma . Most hemangiomas will regress spontaneously , but treatment as early as possible with the appropriate modality can provide better results , especially with the new therapeutic modalities such promising class of beta blockers . Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

74 citations

Journal ArticleDOI
23 Jul 2022-Foods
TL;DR: A review of the research progress into bio-based nanocarriers for the improvement of the oral bioavailability of polyphenols can be found in this paper , where the authors summarized the health benefits of plant polyphenol in the prevention of various diseases.
Abstract: Plant polyphenols have attracted considerable attention because of their key roles in preventing many diseases, including high blood sugar, high cholesterol, and cancer. A variety of functional foods have been designed and developed with plant polyphenols as the main active ingredients. Polyphenols mainly come from vegetables and fruits and can generally be divided according to their structure into flavonoids, astragalus, phenolic acids, and lignans. Polyphenols are a group of plant-derived functional food ingredients with different molecular structures and various biological activities including antioxidant, anti-inflammatory, and anticancer properties. However, many polyphenolic compounds have low oral bioavailability, which limits the application of polyphenols in nutraceuticals. Fortunately, green bio-based nanocarriers are well suited for encapsulating, protecting, and delivering polyphenols, thereby improving their bioavailability. In this paper, the health benefits of plant polyphenols in the prevention of various diseases are summarized, with a review of the research progress into bio-based nanocarriers for the improvement of the oral bioavailability of polyphenols. Polyphenols have great potential for application as key formulations in health and nutrition products. In the future, the development of food-grade delivery carriers for the encapsulation and delivery of polyphenolic compounds could well solve the limitations of poor water solubility and low bioavailability of polyphenols for practical applications.

30 citations

Journal ArticleDOI
TL;DR: Parkinson's disease (PD) is the second most common age-associated neurodegenerative disorder and is characterised by progressive loss of dopamine neurons in the substantia nigra as mentioned in this paper .

19 citations

Journal ArticleDOI
TL;DR: A literature review of the plant origin natural compounds with biocidal properties is presented in this paper, where polyphenols, selected phenols, naphthoquinones, triterpenoids, and phytoncides are natural antibiotics.
Abstract: The article presents a literature review of the plant origin natural compounds with biocidal properties. These compounds could be used as modifiers of biodegradable materials. Modification of polymer material is one of the basic steps in its manufacturing process. Biodegradable materials play a key role in the current development of materials engineering. Natural modifiers are non-toxic, environmentally friendly, and renewable. The substances contained in natural modifiers exhibit biocidal properties against bacteria and/or fungi. The article discusses polyphenols, selected phenols, naphthoquinones, triterpenoids, and phytoncides that are natural antibiotics. Due to the increasing demand for biodegradable materials and the protection of the natural environment against the negative effects of toxic substances, it is crucial to replace synthetic modifiers with plant ones. This work mentions industries where materials containing natural modifying additives could find potential applications. Moreover, the probable examples of the final products are presented. Additionally, the article points out the current world’s pandemic state and the use of materials with biocidal properties considering the epidemiological conditions.

6 citations