P
Paul A. Liberator
Researcher at Pfizer
Publications - 105
Citations - 6252
Paul A. Liberator is an academic researcher from Pfizer. The author has contributed to research in topics: Hybridization probe & cGMP-dependent protein kinase. The author has an hindex of 34, co-authored 99 publications receiving 5789 citations. Previous affiliations of Paul A. Liberator include Merck & Co. & Merial.
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Journal ArticleDOI
A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release
Andrew D. Howard,Scott D. Feighner,Doris F. Cully,Joseph P. Arena,Paul A. Liberator,Charles Rosenblum,Michel J. Hamelin,Donna L. Hreniuk,Oksana C. Palyha,Jennifer W. Anderson,Philip S. Paress,Carmen Diaz,Michael Chou,Ken K. Liu,Karen K. McKee,Sheng-Shung Pong,Lee-Yuh Chaung,Alex Elbrecht,Mike Dashkevicz,Robert P. Heavens,Michael Rigby,Dalip J. S. Sirinathsinghji,Dennis C. Dean,David G. Melillo,Arthur A. Patchett,Ravi P. Nargund,Patrick R. Griffin,Julie A. DeMartino,Sunil Gupta,James M. Schaeffer,Roy G. Smith,Lex H.T. Van der Ploeg +31 more
TL;DR: A heterotrimeric GTP-binding protein (G protein)-coupled receptor (GPC-R) of the pituitary and arcuate ventro-medial and infundibular hypothalamus of swine and humans was cloned and was shown to be the target of the GHSs.
Journal ArticleDOI
Phylogenetic relationships among eight Eimeria species infecting domestic fowl inferred using complete small subunit ribosomal DNA sequences.
John R. Barta,Donald S. Martin,Paul A. Liberator,Michael Dashkevicz,Jennifer W. Anderson,Scott D. Feighner,Alex Elbrecht,Ann Perkins-barrow,Mark C. Jenkins,Harry D. Danforth,M. D. Ruff,Helen Profous-Juchelka +11 more
TL;DR: Clades of avian Eimeria species and the apparent absence of coccidia that infect the ceca of jungle fowl all suggest that E. necatrix and E. tenella may have arisen from a host switch, perhaps from the North American turkey, Meleagris gallopavo.
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Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior
Birgit T. Priest,Beth Ann Murphy,Jill A. Lindia,Carmen Diaz,Catherine Abbadie,Amy M. Ritter,Paul A. Liberator,Leslie M. Iyer,Shera F. Kash,Martin Köhler,Gregory J. Kaczorowski,D. Euan MacIntyre,William J. Martin +12 more
TL;DR: The results suggest that inflammatory mediators modify the function of NaV1.9 to maintain inflammation-induced hyperalgesia and contribute to the persistent thermal hypersensitivity and spontaneous pain behavior after peripheral inflammation.
Journal ArticleDOI
The Antifungal Echinocandin Caspofungin Acetate Kills Growing Cells of Aspergillus fumigatus In Vitro
Joel Bowman,P. Scott Hicks,Myra B. Kurtz,Hugh Rosen,Dennis M. Schmatz,Paul A. Liberator,Cameron M. Douglas +6 more
TL;DR: D dye-staining patterns illustrate that the cells at the active centers for new cell wall synthesis within A. fumigatus hyphae are killed when they are exposed to caspofungin, an antifungal antibiotic that inhibits synthesis of 1,3-β-d-glucan, an essential component of the fungal cell wall.
Journal ArticleDOI
Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate.
Joel Bowman,George K. Abruzzo,Jennifer W. Anderson,Amy M. Flattery,Charles Gill,V. B. Pikounis,Dennis M. Schmatz,Paul A. Liberator,Cameron M. Douglas +8 more
TL;DR: The qPCR assay is superior to traditional CFU determination for monitoring the progression of disseminated aspergillosis and evaluating the activity of antifungal antibiotics against A. fumigatus.