P
Paul B. Hoffer
Researcher at Yale University
Publications - 64
Citations - 5400
Paul B. Hoffer is an academic researcher from Yale University. The author has contributed to research in topics: Iomazenil & Spect imaging. The author has an hindex of 31, co-authored 64 publications receiving 5277 citations. Previous affiliations of Paul B. Hoffer include Montreal Neurological Institute and Hospital & Veterans Health Administration.
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Journal ArticleDOI
Computerized three‐dimensional segmented human anatomy
I. George Zubal,Charles R. Harrell,Eileen O. Smith,Zachary Rattner,Gene Gindi,Paul B. Hoffer +5 more
TL;DR: A computerized 3-dimensional volume array modeling all major internal structures of the body has been created and can serve as a voxel-based anthropomorphic phantom suitable for many computer-based modeling and simulation calculations.
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Unilateral Transplantation of Human Fetal Mesencephalic Tissue into the Caudate Nucleus of Patients with Parkinson's Disease
Dennis D. Spencer,Richard J. Robbins,Frederick Naftolin,Kenneth Marek,Timothy Vollmer,Csaba Leranth,Robert H. Roth,Lawrence H. Price,Albert Gjedde,Benjamin S. Bunney,Kimberlee J. Sass,John D. Elsworth,E. Leon Kier,Robert W. Makuch,Paul B. Hoffer,D. Eugene Redmond +15 more
TL;DR: Although the case patients with severe Parkinson's disease continued to be disabled by their disease, unilateral intracaudate grafts of fetal tissue containing dopamine diminished the symptoms and signs of parkinsonism during 18 months of evaluation.
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Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease.
John Seibyl,K. L. Marchek,Donald M. Quinlan,K Sheff,Sami S. Zoghbi,Yolanda Zea-Ponce,Ronald M. Baldwin,B. Fussell,Eileen O. Smith,D.S. Charney,Paul B. Hoffer,Robert B. Innis +11 more
TL;DR: The significant correlation of SPECT measures with motor severity suggests {123I}β‐CIT may be a useful Marchker of disease severity in PD.
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SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.
Marc Laruelle,Ronald M. Baldwin,Robert T. Malison,Yolanda Zea-Ponce,Sami S. Zoghbi,Mohammed S. Al-Tikeriti,Elzbieta H. Sybirska,Ralph C. Zimmermann,Gary Wisniewski,John L. Neumeyer,Richard A. Milius,Shaoyin Wang,Eileen O. Smith,Robert H. Roth,Dennis S. Charney,Paul B. Hoffer,Robert B. Innis +16 more
TL;DR: It is suggested that [123I]β‐CIT will be a useful SPECT tracer of DA and 5‐HT transporters in living human brain.
Journal ArticleDOI
Diagnostic utility of contrast echocardiography and lung perfusion scan in patients with hepatopulmonary syndrome
TL;DR: Contrast echocardiography is the most useful screening test for intrapulmonary vasodilatation and may be positive more frequently than lung perfusion scans in patients with HPS.