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Paul C. Kuo
Researcher at University of South Florida
Publications - 413
Citations - 14604
Paul C. Kuo is an academic researcher from University of South Florida. The author has contributed to research in topics: Transplantation & Osteopontin. The author has an hindex of 64, co-authored 389 publications receiving 13445 citations. Previous affiliations of Paul C. Kuo include Beth Israel Deaconess Medical Center & DePaul University.
Papers
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Journal ArticleDOI
The role of Osteopontin in tumor metastasis
Philip Y. Wai,Paul C. Kuo +1 more
TL;DR: The following review will discuss the molecular structure of OPN, the evidence for its functional role in tumor cell metastasis, the downstream signals that activate invasive mechanisms, and the recent reports concerning regulation of ONP transcription.
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Osteopontin: regulation in tumor metastasis
Philip Y. Wai,Paul C. Kuo +1 more
TL;DR: The current state of knowledge of OPN biology suggests that it is an attractive target for therapeutic modulation of metastatic disease.
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Predictive Indices of Morbidity and Mortality After Liver Resection
Rebecca A. Schroeder,Carlos E. Marroquin,Barbara Phillips Bute,Shukri F. Khuri,William G. Henderson,Paul C. Kuo +5 more
TL;DR: The Model for End-Stage Liver Disease (MELD) score was originally developed to predict short-term survival in patients undergoing transcutaneous intrahepatic portosystemic shunt procedures (TIPS), and has been shown to be reliable and predictive in this setting.
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The Emerging Multifaceted Roles of Nitric Oxide
Paul C. Kuo,Rebecca A. Schroeder +1 more
TL;DR: This review is an attempt to acquaint the surgical community with the fundamentals of NO biochemistry and physiology and to enable physicians to better understand these disease processes and utilize new pharmacologic therapies.
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Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis
Wing-Kin Syn,Wing-Kin Syn,Steve S. Choi,Steve S. Choi,Evaggelia Liaskou,Gamze Karaca,Kolade M. Agboola,Ye Htun Oo,Zhiyong Mi,Thiago A. Pereira,Thiago A. Pereira,Marzena Zdanowicz,Padmini Malladi,Yuping Chen,Cynthia A. Moylan,Cynthia A. Moylan,Youngmi Jung,Youngmi Jung,Syamal D. Bhattacharya,Vanessa Teaberry,Alessia Omenetti,Manal F. Abdelmalek,Cynthia D. Guy,David H. Adams,Paul C. Kuo,Gregory A. Michelotti,Peter F. Whitington,Anna Mae Diehl +27 more
TL;DR: It is hypothesized that Hh signaling induces OPN to promote liver fibrosis in NASH and OPN inhibition may be beneficial inNASH, because OPN induction correlates with Hh pathway activity and fibrosis stage.