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Paul Cordo

Bio: Paul Cordo is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Motor control & Muscle spindle. The author has an hindex of 22, co-authored 48 publications receiving 2334 citations.

Papers
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Journal ArticleDOI
15 Apr 2000-Spine
TL;DR: Patients with low back pain have a less refined position sense than healthy individuals, possibly because of an altered paraspinal muscle spindle afference and central processing of this sensory input, and muscle vibration can be an interesting expedient for improving proprioception and enhancing local muscle control.
Abstract: Study Design.A two-group experimental design with repeated measures on one factor was used.Objectives.To investigate the role of paraspinal muscle spindles in lumbosacral position sense in individuals with and without low back pain.Summary of Background Data.Proprioceptive deficits have been identif

462 citations

Journal ArticleDOI
TL;DR: The results suggest that spinal pain and aging may lead to changes in postural control by refocusing proprioceptive sensitivity from the trunk to the ankles.

259 citations

Journal ArticleDOI
TL;DR: The absence of a levodopa effect on axial tone suggests that axial and appendicular tones are controlled by separate neural circuits, and hypertonicity may underlie functional impairments of posture and locomotion in PD.

125 citations

Journal ArticleDOI
TL;DR: The results showed that aging lead to a significant increase in deviation from the target angle at hand opening as well as in variability of performance, suggesting that the age-related decline in performance on the dynamic position sense task is not (solely) due to muscle spindle function changes.

115 citations


Cited by
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Journal ArticleDOI
06 Jun 1986-JAMA
TL;DR: The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Abstract: I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

7,563 citations

Journal ArticleDOI
TL;DR: How noise affects neuronal networks and the principles the nervous system applies to counter detrimental effects of noise are highlighted, and noise's potential benefits are discussed.
Abstract: Noise — random disturbances of signals — poses a fundamental problem for information processing and affects all aspects of nervous-system function. However, the nature, amount and impact of noise in the nervous system have only recently been addressed in a quantitative manner. Experimental and computational methods have shown that multiple noise sources contribute to cellular and behavioural trial-to-trial variability. We review the sources of noise in the nervous system, from the molecular to the behavioural level, and show how noise contributes to trial-to-trial variability. We highlight how noise affects neuronal networks and the principles the nervous system applies to counter detrimental effects of noise, and briefly discuss noise's potential benefits.

2,350 citations

Journal ArticleDOI
TL;DR: Proprioceptive senses, particularly of limb position and movement, deteriorate with age and are associated with an increased risk of falls in the elderly and the more recent information available on proprioception has given a better understanding of the mechanisms underlying these senses.
Abstract: This is a review of the proprioceptive senses generated as a result of our own actions. They include the senses of position and movement of our limbs and trunk, the sense of effort, the sense of force, and the sense of heaviness. Receptors involved in proprioception are located in skin, muscles, and joints. Information about limb position and movement is not generated by individual receptors, but by populations of afferents. Afferent signals generated during a movement are processed to code for endpoint position of a limb. The afferent input is referred to a central body map to determine the location of the limbs in space. Experimental phantom limbs, produced by blocking peripheral nerves, have shown that motor areas in the brain are able to generate conscious sensations of limb displacement and movement in the absence of any sensory input. In the normal limb tendon organs and possibly also muscle spindles contribute to the senses of force and heaviness. Exercise can disturb proprioception, and this has implications for musculoskeletal injuries. Proprioceptive senses, particularly of limb position and movement, deteriorate with age and are associated with an increased risk of falls in the elderly. The more recent information available on proprioception has given a better understanding of the mechanisms underlying these senses as well as providing new insight into a range of clinical conditions.

1,280 citations

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TL;DR: Stochastic resonance is a ubiquitous and conspicuous phenomenon compatible with neural models and theories of brain function and should encourage neuroscientists and clinical neurophysiologists to explore stochastic resonance in biology and medical science.

874 citations

Journal ArticleDOI
TL;DR: A review of robotic devices for upper limb rehabilitation including those in developing phase is document in order to provide a comprehensive reference about existing solutions and facilitate the development of new and improved devices.
Abstract: The existing shortage of therapists and caregivers assisting physically disabled individuals at home is expected to increase and become serious problem in the near future The patient population needing physical rehabilitation of the upper extremity is also constantly increasing Robotic devices have the potential to address this problem as noted by the results of recent research studies However, the availability of these devices in clinical settings is limited, leaving plenty of room for improvement The purpose of this paper is to document a review of robotic devices for upper limb rehabilitation including those in developing phase in order to provide a comprehensive reference about existing solutions and facilitate the development of new and improved devices In particular the following issues are discussed: application field, target group, type of assistance, mechanical design, control strategy and clinical evaluation This paper also includes a comprehensive, tabulated comparison of technical solutions implemented in various systems

851 citations