P
Paul G. Richardson
Researcher at Harvard University
Publications - 1631
Citations - 174221
Paul G. Richardson is an academic researcher from Harvard University. The author has contributed to research in topics: Multiple myeloma & Bortezomib. The author has an hindex of 183, co-authored 1533 publications receiving 155912 citations. Previous affiliations of Paul G. Richardson include Broomfield Hospital & Dartmouth College.
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Journal ArticleDOI
Results of the Pivotal STORM Study (Part 2) in Penta-Refractory Multiple Myeloma (MM): Deep and Durable Responses with Oral Selinexor Plus Low Dose Dexamethasone in Patients with Penta-Refractory MM
Ajai Chari,Dan T. Vogl,Meletios A. Dimopoulos,Ajay K. Nooka,Carol Ann Huff,Philippe Moreau,Craig E. Cole,Joshua Richter,David Dingli,Ravi Vij,Sascha A. Tuchman,Marc S. Raab,Katja Weisel,Michel Delforge,David Kaminetzky,Robert F. Cornell,A. Keith Stewart,James E. Hoffman,Kelly N. Godby,Terri L. Parker,Moshe Yair Levy,Martin Schreder,Nathalie Meuleman,Laurent Frenzel,Mohamad Mohty,Choquet Sylvain,Andrew Yee,Maria Gavriatopoulou,Luciano J. Costa,Jatin J. Shah,Carla Picklesimer,Jean-Richard Saint-Martin,Lingling Li,Michael Kauffman,Sharon Shacham,Paul G. Richardson,Sundar Jagannath +36 more
TL;DR: The Pivotal Part 2 of STORM was initiated, enrolling an additional cohort of 122 patients with penta-refractory MM, and demonstrated an overall response rate (ORR) of 21% that met the inclusion criteria for STORM.
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Blockade of PD-1 in Combination with Dendritic Cell/Myeloma Fusion Cell Vaccination Following Autologous Stem Cell Transplantation Is Well Tolerated, Induces Anti-Tumor Immunity and May Lead to Eradication of Measureable Disease
Jacalyn Rosenblatt,Irit Avivi,Noam Binyamini,Lynne Uhl,Poorvi Somaiya,Dina Stroopinsky,Kristen Palmer,Maxwell D. Coll,Tami Katz,Lina Bisharat,Robin Joyce,James D. Levine,Jon E. Arnason,Katarina Luptakova,Malgorzata McMasters,Salvia Jain,Merav Leiba,Aya Sato-DiLorenzo,Emma Logan,Mary Paty Bryant,Viki Held,Paul G. Richardson,Jacob P. Laubach,Arnon Nagler,Kenneth C. Anderson,Nikhil C. Munshi,Jacob M. Rowe,Donald Kufe,David Avigan +28 more
TL;DR: A cancer vaccine in which dendritic cells are fused to autologous tumor cells resulting in the presentation of multiple tumor antigens with the capacity to elicit a broad anti-tumor response was developed, which resulted in the eradication of post-transplant measurable disease.
Journal ArticleDOI
Updated Results of a Phase 2 Study of Modified Lenalidomide, Bortezomib, and Dexamethasone (RVd-lite) in Transplant-Ineligible Multiple Myeloma
Elizabeth O'Donnell,Jacob P. Laubach,Andrew Yee,Robert A. Redd,Carol Ann Huff,Frank G. Basile,Philip M. Wade,Claudia E. Paba-Prada,Irene M. Ghobrial,Robert L. Schlossman,Jill N. Burke,Cynthia C. Harrington,Kathleen J. Lively,Hannah Lyons,Nikhil C. Munshi,Kenneth C. Anderson,Paul G. Richardson,Noopur Raje +17 more
TL;DR: RVD lite is a well-tolerated and highly effective regimen in the transplant-ineligible population with robust PFS and OS and the data demonstrates that the benefits of more effective combination strategies observed in younger, fitter, transplant-eligible patients to older, transplanted patients with modifications in dose and schedule, without compromising efficacy.
Journal ArticleDOI
Pomalidomide (POM) with or without low-dose dexamethasone (LoDEX) in patients (Pts) with relapsed and refractory multiple myeloma (RRMM): MM-002 phase II age subgroup analysis.
Sundar Jagannath,Craig C. Hofmeister,Rachid Baz,David S. Siegel,Ravi Vij,Christine Chen,Sagar Lonial,Kenneth C. Anderson,Min Chen,Mohamed H. Zaki,Paul G. Richardson +10 more
TL;DR: This analysis evaluated whether the efficacy and tolerability of POM+LoDEX treatment is consistent across age subgroups and found the most common treatment emergent grade 3/4 adverse events (AEs) for the age sub groups accorded.
Journal ArticleDOI
Use of Antiretroviral Drug Testing to Assess the Accuracy of Self-reported Data from HIV-Infected People Who Inject Drugs
Jessica M. Fogel,Yinfeng Zhang,Philip J. Palumbo,Xu Guo,William Clarke,Autumn Breaud,Paul G. Richardson,Estelle Piwowar-Manning,Erica L. Hamilton,Tran Viet Ha,Kostyantyn Dumchev,Zubairi Djoerban,Irving F. Hoffman,Brett Hanscom,William C. Miller,Susan H. Eshleman +15 more
TL;DR: This study shows that self-reported data on HIV testing history and ART may not be accurate and that ARV drug testing can help identify persons who are aware of their HIV-positive status and are on ART.