Paul S. Myles

TL;DR: The present guidelines are the most recent data on postoperative nausea and vomiting (PONV) and an update on the 2 previous sets of guidelines published in 2003 and 2007.

TL;DR: BIS-guided anaesthesia reduces the risk of awareness in at-risk adult surgical patients undergoing relaxant general anaesthesia, and with a cost of routine BIS monitoring at US16 dollars per use in Australia and a number needed to treat of 138, the cost of preventing one case ofawareness in high-risk patients is about 2200 dollars.

TL;DR: Most adverse morbid outcomes in high-risk patients undergoing major abdominal surgery are not reduced by use of combined epidural and general anaesthesia and postoperative epidural analgesia, however, the improvement in analgesIA, reduction in respiratory failure, and the low risk of serious adverse consequences suggest that many high- risk patients undergo major intra-abdominal surgery will receive substantial benefit from combined general and epidural anaesthesia intraoperatively with continuing postoperative analgesia.

TL;DR: There was a strong relation between patient dissatisfaction and: intraoperative awareness, moderate or severe postoperative pain, and several factors associated with dissatisfaction which may be preventable or better treated.

TL;DR: These guidelines identify risk factors for PonV in adults and children; recommend approaches for reducing baseline risks for PONV; identify the most effective antiemetic monotherapy and combination therapy regimens for P ONV prophylaxis; recommend approach for treatment of PONv when it occurs; and provide an algorithm for the management of individuals at increased risk for POnV.