P
Paulo H.M. Chaves
Researcher at Johns Hopkins University
Publications - 76
Citations - 9422
Paulo H.M. Chaves is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Population & Anemia. The author has an hindex of 48, co-authored 71 publications receiving 8689 citations. Previous affiliations of Paulo H.M. Chaves include Rio de Janeiro State University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Phenotype of Frailty: Characterization in the Women's Health and Aging Studies
Karen Bandeen-Roche,Qian Li Xue,Luigi Ferrucci,Jeremy D. Walston,Jack M. Guralnik,Paulo H.M. Chaves,Scott L. Zeger,Linda P. Fried +7 more
TL;DR: The frailty definition developed in the CHS is applicable across diverse population samples and identifies a profile of high risk of multiple adverse outcomes and is consistent with the widely held theory that conceptualizes frailty as a syndrome.
Journal ArticleDOI
Preclinical Mobility Disability Predicts Incident Mobility Disability in Older Women
TL;DR: Two indicators of functional changes in older women without mobility difficulty, self-report of modification of method of doing a task in the absence of difficulty and performance measures, are independent and strong predictors of risk of incident mobility disability.
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Nonlinear Multisystem Physiological Dysregulation Associated With Frailty in Older Women: Implications for Etiology and Treatment
Linda P. Fried,Qian Li Xue,Anne R. Cappola,Luigi Ferrucci,Paulo H.M. Chaves,Ravi Varadhan,Jack M. Guralnik,Sean X. Leng,Richard D. Semba,Jeremy D. Walston,Caroline S. Blaum,Caroline S. Blaum,Karen Bandeen-Roche +12 more
TL;DR: It is shown that a threshold loss of complexity, as indicated by number of systems abnormal, may undermine homeostatic adaptive capacity, leading to the development of frailty and its associated risk for subsequent adverse outcomes.
Journal ArticleDOI
Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study.
Stefano Volpato,Jack M. Guralnik,Luigi Ferrucci,Jennifer L. Balfour,Paulo H.M. Chaves,Linda P. Fried,Tamara B. Harris +6 more
TL;DR: IL-6 level is helpful in identifying a subgroup of older CVD patients with high risk of death over a period of 3 years, and may be related to the clinical evolution of older patients with CVD.
Journal ArticleDOI
A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort: the Cardiovascular Health Study.
Neil A. Zakai,Ronit Katz,Calvin H. Hirsch,Michael G. Shlipak,Paulo H.M. Chaves,Anne B. Newman,Mary Cushman +6 more
TL;DR: In this article, the authors assessed baseline hemoglobin quintiles and anemia in relation to mortality in the Cardiovascular Health Study, a prospective cohort study with 11.2 years of follow-up of 5888 community-dwelling men and women 65 years or older, enrolled in 1989-1990 or 1992-1993 in 4 US communities.