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Paulus Kirchhof
Researcher at University of Birmingham
Publications - 659
Citations - 119822
Paulus Kirchhof is an academic researcher from University of Birmingham. The author has contributed to research in topics: Atrial fibrillation & Medicine. The author has an hindex of 100, co-authored 558 publications receiving 106459 citations. Previous affiliations of Paulus Kirchhof include United States Department of Veterans Affairs & Georgetown University Medical Center.
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Journal ArticleDOI
Genetic and Clinical Predictors of Left Atrial Thrombus: A Single Center Case-Control Study.
Adrian Springer,Ruben Schleberger,Florian Oyen,Boris A. Hoffmann,Stephan Willems,Christian Meyer,Florian Langer,Renate B. Schnabel,Paulus Kirchhof,Paulus Kirchhof,Reinhard Schneppenheim,Marc D Lemoine +11 more
TL;DR: In this article, left atrial thrombus formation is the presumed origin of thromboembolic complications in patients with atrial fibrillation (AF) in patients.
Journal Article
Abstract 18782: Regional Action Potential Heterogeneity in the Murine Pitx2c Deficient Left Atrium
TL;DR: Compared regional action potential (AP) morphology in PITX2c+/- and wild type (WT) littermate mice, partial depletion in Pitx2c mRNA expression causes a uniform APD shortening throughout the LA and loss of regional changes in AP amplitude.
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Improving outcomes after catheter ablation of atrial fibrillation: better patient selection, better procedure, or both?
TL;DR: A systematic analysis of temporal trends ofAF ablation success rates in an unselected population undergoing a first AF ablation in clinical practice and the rates of repeat ablation appear to be comparable to other large cohorts.
Journal ArticleDOI
Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle
Paula Münkler,Niklas Klatt,Katharina Scherschel,Pawel Kuklik,Christiane Jungen,Ersin Cavus,Christian Eickholt,Jan Christoph,Marc D Lemoine,Torsten Christ,Stephan Willems,René Riedel,Paulus Kirchhof,Christian Meyer +13 more
TL;DR: The parameter repolarization time in relation to cycle length (RT/CL) is found to differentiate self-limiting from degenerating arrhythmia with high specificity and sensitivity and may serve as a simple index to aid differentiation between self- Limiting and electrically instable arrhythmias with the propensity to degenerate to VF.
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Complex antithrombotic combinations: how to find the perfect blend?
TL;DR: The optimal combination of aspirin, platelet P2Y12 inhibitor and anticoagulant is still unknown, and a one-size-fits-all approach may never be possible, but five randomised controlled trials on this topic have taught us that discontinuation of aspirin significantly reduces the risk of major bleeding.