P
Paulus Kirchhof
Researcher at University of Birmingham
Publications - 659
Citations - 119822
Paulus Kirchhof is an academic researcher from University of Birmingham. The author has contributed to research in topics: Atrial fibrillation & Medicine. The author has an hindex of 100, co-authored 558 publications receiving 106459 citations. Previous affiliations of Paulus Kirchhof include United States Department of Veterans Affairs & Georgetown University Medical Center.
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Journal ArticleDOI
Depression in paroxysmal and persistent atrial fibrillation patients: a cross-sectional comparison of patients enroled in two large clinical trials
Alexander von Eisenhart Rothe,Andreas Goette,Paulus Kirchhof,Günter Breithardt,Tobias Limbourg,Melanie Calvert,Jens Baumert,Karl-Heinz Ladwig +7 more
TL;DR: Persistent AF patients may suffer from more severe depressed mood than paroxysmal AF patients with similar symptom burden after controlling for relevant factors.
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Gene dose-dependent atrial arrhythmias, heart block, and brady-cardiomyopathy in mice overexpressing A3 adenosine receptors
Larissa Fabritz,Paulus Kirchhof,Lisa Fortmüller,John A. Auchampach,Hideo Baba,Günter Breithardt,Joachim Neumann,Peter Boknik,Wilhelm Schmitz +8 more
TL;DR: Heart-directed overexpression of A(3)AR resulted in gene dose-dependent AV block and pronounced sinus nodal dysfunction in vivo, which may have implications for the physiology of sinu nodal regulation and for therapeutic attempts to increase the expression of adenosine receptors.
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Temporal trends in incidence, causes, use of mechanical circulatory support and mortality in cardiogenic shock.
Benedikt Schrage,Peter Moritz Becher,Alina Goßling,Gianluigi Savarese,Salim Dabboura,Isabell Yan,Benedikt N Beer,Gerold Söffker,Moritz Seiffert,Stefan Kluge,Paulus Kirchhof,Stefan Blankenberg,Dirk Westermann +12 more
TL;DR: In this paper, the authors describe temporal trends in incidence, causes, use of mechanical circulatory support, and mortality in cardiogenic shock in Germany, and highlight the need to address the evidence gap in this field, in particular for patients suffering from diseases other than acute myocardial infarction.
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Risk factors for thromboembolic and bleeding events in anticoagulated patients with atrial fibrillation: the prospective, multicentre observational PREvention oF thromboembolic events - European Registry in Atrial Fibrillation (PREFER in AF)
Miklos Rohla,Thomas W. Weiss,Ladislav Pecen,Giuseppe Patti,Jolanta M. Siller-Matula,Renate B. Schnabel,Richard J. Schilling,Dipak Kotecha,Markus Lucerna,Kurt Huber,Raffaele De Caterina,Paulus Kirchhof +11 more
TL;DR: Abnormal liver function, prior stroke or transient ischaemic attack, labile international normalised ratio (INR), concomitant therapy with antiplatelet or non-steroidal anti-inflammatory drugs, heart failure and older age were independently associated with both thromboembolic and major bleeding events.
Journal ArticleDOI
Load-induced changes in repolarization: evidence from experimental and clinical data
TL;DR: If mechanical disorders play a central role in the genesis of cardiac arrhythmias, future treatment should be directed at restoring a more normal mechanical function of the heart.