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Pedram Hamrah
Researcher at Tufts University
Publications - 276
Citations - 9308
Pedram Hamrah is an academic researcher from Tufts University. The author has contributed to research in topics: Cornea & Medicine. The author has an hindex of 45, co-authored 253 publications receiving 7369 citations. Previous affiliations of Pedram Hamrah include University of Louisville & Boston Children's Hospital.
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Journal ArticleDOI
TFOS DEWS II pain and sensation report
Carlos Belmonte,Jason J. Nichols,Stephanie Cox,James A. Brock,Carolyn G. Begley,David A. Bereiter,Darlene A. Dartt,Anat Galor,Anat Galor,Pedram Hamrah,Jason J. Ivanusic,Deborah S. Jacobs,Nancy A. McNamara,Nancy A. McNamara,Mark I. Rosenblatt,Fiona Stapleton,James S. Wolffsohn +16 more
TL;DR: Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect wetness and reflexly maintain basal tear production and blinking rate, thereby evoking dryness sensations and pain.
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The corneal stroma is endowed with a significant number of resident dendritic cells.
TL;DR: This study demonstrates that, in addition to the known Langerhans cells in the corneal epithelium, at least three BM-derived cell subsets reside in the normal corneale stroma.
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Corneal immunity is mediated by heterogeneous population of antigen-presenting cells
TL;DR: Recent data are presented demonstrating that the central cornea is indeed endowed with a heterogeneous population of epithelial and stromal DC, which function as APC, and suggesting that the corneal system is capable of diverse cellular mechanisms for antigen presentation.
Journal Article
Novel characterization of MHC class II-negative population of resident corneal Langerhans cell-type dendritic cells.
TL;DR: The present study demonstrates for the first time the phenotype and distribution of MHC class II-negative LCs in the murine corneal epithelium and changes in activation markers may provide additional information for devising novel immunomodulatory strategies.
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Corneal Sensation and Subbasal Nerve Alterations in Patients with Herpes Simplex Keratitis: An In Vivo Confocal Microscopy Study
Pedram Hamrah,Andrea Cruzat,Mohammad H. Dastjerdi,Lixin Zheng,Bashar M. Shahatit,Hasan Ali Bayhan,Reza Dana,Deborah Pavan-Langston +7 more
TL;DR: In vivo confocal microscopy revealed that the loss of corneal sensation in HSK correlates strongly with profound diminishment of the subbasal nerve plexus after herpes simplex virus infection.