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Peer F Staehler
Researcher at Torrey Pines Institute for Molecular Studies
Publications - 26
Citations - 717
Peer F Staehler is an academic researcher from Torrey Pines Institute for Molecular Studies. The author has contributed to research in topics: Nucleic acid & Analyte. The author has an hindex of 7, co-authored 26 publications receiving 678 citations.
Papers
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Journal ArticleDOI
Toward the blood-borne miRNome of human diseases
Andreas Keller,Petra Leidinger,Andrea S. Bauer,Abdou ElSharawy,Jan Haas,Christina Backes,Anke Wendschlag,Nathalia Giese,Christine Tjaden,Katja Ott,Jens Werner,Thilo Hackert,Klemens Ruprecht,Hanno Huwer,Junko Huebers,Gunnar Jacobs,Philip Rosenstiel,Henrik Dommisch,Arne S. Schaefer,Joachim Müller-Quernheim,Bernd Wullich,Bastian Keck,Norbert Graf,Joerg Reichrath,Britta Vogel,Almut Nebel,Sven Uwe Jager,Peer F Staehler,Ioannis Amarantos,Valesca Boisguerin,Cord F Staehler,Markus Beier,Matthias Scheffler,Markus W. Büchler,J Wischhusen,Sebastian F M Haeusler,Johannes Dietl,Sylvia Hofmann,Hans-Peter Lenhof,Stefan Schreiber,Hugo A. Katus,Wolfgang Rottbauer,Benjamin Meder,Joerg Hoheisel,Andre Franke,Eckart Meese +45 more
TL;DR: In a multicenter study, the expression profiles of 863 microRNAs were determined by array analysis of 454 blood samples from human individuals with different cancers or noncancer diseases, and this 'miRNome' was validated by quantitative real-time PCR.
Journal ArticleDOI
Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis.
Andreas Keller,Petra Leidinger,Randi Elin Gislefoss,Aage Haugen,Hilde Langseth,Peer F Staehler,Hans-Peter Lenhof,Eckart Meese +7 more
TL;DR: The findings support the idea that a developing lung cancer might be detectable years prior to diagnosis through a specific miRNA signature and that this signature changes during tumor development.
Journal ArticleDOI
Tests of rRNA hybridization to microarrays suggest that hybridization characteristics of oligonucleotide probes for species discrimination cannot be predicted
Alex E. Pozhitkov,Peter A. Noble,Tomislav Domazet-Lošo,Arne W. Nolte,Rainer Sonnenberg,Peer F Staehler,Markus Beier,Diethard Tautz +7 more
TL;DR: The results imply that the thermodynamic properties of oligonucleotide hybridization are by far not yet understood, and recommend against the application of probe design software tools that use thermodynamic parameters to assess probe quality for species identification.
Patent
Method for analysis of nucleic acid populations
Markus Beier,Peer F Staehler,Cord F Staehler,Daniel Summerer,Jack T. Leonard,Stephan Bau,Anthony Caruso,Nadine Schracke,Andreas Keller,Helmut Hanenberg,Olaf Eckermann +10 more
TL;DR: In this paper, a method for isolation of target molecules from a nucleic acid population was proposed, which relates to the method described in Section 2.2.1 of this paper.
Patent
Microfluidic extraction method
TL;DR: In this paper, an extraction method for isolating target molecules from a sample using a microfluidic carrier was proposed, which relates to the extraction method described in this paper.