P
Pekka Saikku
Researcher at University of Helsinki
Publications - 76
Citations - 8035
Pekka Saikku is an academic researcher from University of Helsinki. The author has contributed to research in topics: Chlamydia & Chlamydia trachomatis. The author has an hindex of 42, co-authored 76 publications receiving 7965 citations. Previous affiliations of Pekka Saikku include University of Oulu & University of Washington.
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Journal ArticleDOI
Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction.
Pekka Saikku,Pekka Saikku,Kimmo Mattila,Kimmo Mattila,Markku S. Nieminen,Markku S. Nieminen,Jussi K. Huttunen,Jussi K. Huttunen,Maija Leinonen,Maija Leinonen,M. R. Ekman,M. R. Ekman,P H Mäkelä,P H Mäkelä,Ville Valtonen,Ville Valtonen +15 more
TL;DR: Investigation for antibodies to a novel type of Chlamydia sp, TWAR, and to chlamydial lipopolysaccharide (LPS) group antigen found they could be a factor in the pathogenesis of cardiovascular diseases.
Journal ArticleDOI
Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
Journal ArticleDOI
A New Respiratory Tract Pathogen: Chlamydia pneumoniae Strain TWAR
J. Thomas Grayston,Lee Ann Campbell,Cho-Chou Kuo,Carl H. Mordhorst,Pekka Saikku,David H. Thorn,San-Pin Wang +6 more
TL;DR: Chlamydia pneumoniae strain TWAR, the new third species of Chlamydia, is a common cause of pneumonia and other acute respiratory tract infections as mentioned in this paper, and about 10% of hospitalized and outpatient pneumonia cases have been associated with TWAR infection.
Journal ArticleDOI
Chlamydia pneumoniae-specific circulating immune complexes in patients with chronic coronary heart disease.
TL;DR: In this paper, the authors investigated whether C. pneumoniae species-specific immune complexes are present in chronic coronary heart disease and found that the majority of the patients with chronic C. pneumocystis pneumoniae infection have chlamydial components having an easy access to circulation to form immune complexes with preexisting antibodies.
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An Epidemic of Mild Pneumonia Due to an Unusual Strain of Chlamydia psittaci
TL;DR: Microimmunofluorescence antibody tests suggest that the etiologic agent is closely related or identical to TW-183, an unusual strain of Chlamydia psittaci isolated from the eye of a child in Taiwan.