P
Peng Li
Researcher at New York Medical College
Publications - 40
Citations - 3369
Peng Li is an academic researcher from New York Medical College. The author has contributed to research in topics: Myocyte & Ventricle. The author has an hindex of 27, co-authored 40 publications receiving 3300 citations.
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Journal ArticleDOI
Stretch-induced programmed myocyte cell death.
Wei Cheng,Baosheng Li,Jan Kajstura,Peng Li,Michael S. Wolin,Edmund H. Sonnenblick,Thomas H. Hintze,Giorgio Olivetti,Piero Anversa +8 more
TL;DR: Overstretching appears to be coupled with oxidant stress, expression of Fas, programmed cell death, architectural rearrangement of myocytes, and impairment in force development of the myocardium.
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Angiotensin II induces apoptosis of adult ventricular myocytes in vitro.
TL;DR: Ligand binding of AT1receptors on myocytes triggers PMCD by a mechanism involving PKC-mediated increases in cytosolic calcium, which result in internucleosomal DNA fragmentation.
Journal ArticleDOI
Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice.
Krzysztof Reiss,Wei Cheng,Andres Ferber,Jan Kajstura,Peng Li,Baosheng Li,Giorgio Olivetti,Charles J. Homcy,Renato Baserga,Piero Anversa +9 more
TL;DR: In conclusion, overexpression of IGF-1 in myocytes leads to cardiomegaly mediated by an increased number of cells in the heart by way of overexposure to rat alpha-myosin heavy chain promoter.
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Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats
Jan Kajstura,Wei Cheng,R. Sarangarajan,Peng Li,Baosheng Li,James A. Nitahara,S. Chapnick,Krzysztof Reiss,Giorgio Olivetti,Piero Anversa +9 more
TL;DR: Myocyte cell death, apoptotic and necrotic in nature, constitutes an important determinant of the aging process, possibly mediating the occurrence of ventricular dysfunction and failure in the old heart.
Journal ArticleDOI
Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats.
Leonard G. Meggs,J. Coupet,Harer Huang,Wei Cheng,Peng Li,J. M. Capasso,C. J. Homcy,Piero Anversa +7 more
TL;DR: Myocardial infarction leads to impairment in the contractile behavior of the remaining cells and to the activation of Ang II receptors and effector pathway associated with these receptors, which may be involved in the reactive growth adaptation of the viable myocytes.