P
Peng Liu
Researcher at University of Pittsburgh
Publications - 30
Citations - 806
Peng Liu is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Catalysis & Enantioselective synthesis. The author has an hindex of 6, co-authored 30 publications receiving 293 citations. Previous affiliations of Peng Liu include University of California, Los Angeles.
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Journal ArticleDOI
Z-Selectivity in Olefin Metathesis with Chelated Ru Catalysts:Computational Studies of Mechanism and Selectivity
Peng Liu,Xiufang Xu,Xiufang Xu,Xiaofei Dong,Benjamin K. Keitz,Myles B. Herbert,Robert H. Grubbs,Kendall N. Houk +7 more
TL;DR: The mechanism and origins of Z-selectivity in olefin metathesis with chelated Ru catalysts were explored using density functional theory to show how Steric repulsions between the substituents on the oleFin and the N-substituent on theN-heterocyclic carbene ligand lead to highly selective formation of the Z product.
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An enzymatic platform for the asymmetric amination of primary, secondary and tertiary C(sp 3)-H bonds
TL;DR: The ability to selectively functionalize ubiquitous C-H bonds streamlines the construction of complex molecular architectures from easily available precursors as discussed by the authors, which can be optimized by directed evolution for a broad spectrum of enantioselective C(sp3)-H amination reactions.
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Cascade CuH-Catalysed Conversion of Alkynes to Enantioenriched 1,1-Disubstituted Products.
De-Wei Gao,Yang Gao,Huiling Shao,Tian-Zhang Qiao,Xin Wang,Brittany Sanchez,Jason S. Chen,Peng Liu,Keary M. Engle +8 more
TL;DR: An efficient strategy to synthesize α-aminoboron compounds by a CuH-catalysed hydroboration/hydroamination cascade of readily available alkynes is reported, offering rapid access to these privileged scaffolds with high chemo-, regio- and enantioselectivity.
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Tandem Iridium Catalysis as a General Strategy for Atroposelective Construction of Axially Chiral Styrenes.
TL;DR: In this paper, the first tandem iridium catalysis was reported for axially chiral styrenes enabled by asymmetric Allylic Substitution-Isomerization (AASI) using cinnamyl carbonate analogues as electrophiles and naphthols as nucleophiles.
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Monovalent Nickel-Mediated Radical Formation: A Concerted Halogen-Atom Dissociation Pathway Determined by Electroanalytical Studies.
TL;DR: In this article, the linear free energy relationship between rates and the bond-dissociation free energies, the electronic and steric effects of the nickel complexes and the electrophiles, and DFT calculations support a variant of the halogen atom abstraction pathway with halogen-atom dissociation.