Author
Peng Liu
Other affiliations: Institute of High Performance Computing Singapore, Purdue University, University of Minnesota ...read more
Bio: Peng Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 64, co-authored 1351 publications receiving 23178 citations. Previous affiliations of Peng Liu include Institute of High Performance Computing Singapore & Purdue University.
Topics: Medicine, Materials science, Chemistry, Computer science, Biology
Papers published on a yearly basis
Papers
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04 Nov 2010TL;DR: A distributed incremental data aggregation approach, in which data aggregation is performed at all smart meters involved in routing the data from the source meter to the collector unit, which is especially suitable for smart grids with repetitive routine data aggregation tasks.
Abstract: In this paper, we present a distributed incremental data aggregation approach, in which data aggregation is performed at all smart meters involved in routing the data from the source meter to the collector unit. With a carefully constructed aggregation tree, the aggregation route covers the entire local neighborhood or any arbitrary set of designated nodes with minimum overhead. To protect user privacy, homomorphic encryption is used to secure the data en route. Therefore, all the meters participate in the aggregation, without seeing any intermediate or final result. In this way, our approach supports efficient data aggregation in smart grids, while fully protecting user privacy. This approach is especially suitable for smart grids with repetitive routine data aggregation tasks.
552 citations
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TL;DR: The model demonstrates that variation and selective retention of patterns of action are necessary and sufficient to explain the features of organizational routines that are most relevant in relation to dynamic capabilities, such as formation, inertia, endogenous change, and learning.
Abstract: This paper introduces a generative model of organizational routines and their change over time. The model demonstrates that variation and selective retention of patterns of action are necessary and sufficient to explain the features of organizational routines that are most relevant in relation to dynamic capabilities, such as formation, inertia, endogenous change, and learning. The model directly links micro-level actions to the macro-level dynamics of routines. The results suggest that focusing on action provides a useful and parsimonious foundation for a theory of organizational routines and capabilities.
371 citations
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TL;DR: The review reveals the change in physicochemical properties of MPs and the release of additives and MP-derived intermediates during weathering processes and the interaction mechanisms of pristine and weathered MPs with pollutants are summarized.
348 citations
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TL;DR: Qualitative approaches for measuring ICD markers in vitro and ex vivo for the discovery of next-generation antineoplastic agents, the development of personalized anticancer regimens, and the identification of optimal therapeutic combinations for the clinical management of cancer are outlined.
Abstract: Chemotherapy, radiation therapy, as well as targeted anticancer agents can induce clinically relevant tumor-targeting immune responses, which critically rely on the antigenicity of malignant cells and their capacity to generate adjuvant signals. In particular, immunogenic cell death (ICD) is accompanied by the exposure and release of numerous damage-associated molecular patterns (DAMPs), which altogether confer a robust adjuvanticity to dying cancer cells, as they favor the recruitment and activation of antigen-presenting cells. ICD-associated DAMPs include surface-exposed calreticulin (CALR) as well as secreted ATP, annexin A1 (ANXA1), type I interferon, and high-mobility group box 1 (HMGB1). Additional hallmarks of ICD encompass the phosphorylation of eukaryotic translation initiation factor 2 subunit-α (EIF2S1, better known as eIF2α), the activation of autophagy, and a global arrest in transcription and translation. Here, we outline methodological approaches for measuring ICD markers in vitro and ex vivo for the discovery of next-generation antineoplastic agents, the development of personalized anticancer regimens, and the identification of optimal therapeutic combinations for the clinical management of cancer.
344 citations
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01 Jun 2012
TL;DR: SPAdes as mentioned in this paper is a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler and on popular assemblers Velvet and SoapDeNovo (for multicell data).
Abstract: The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies of uncultivated organisms. Assembly of single-cell data is challenging because of highly non-uniform read coverage as well as elevated levels of sequencing errors and chimeric reads. We describe SPAdes, a new assembler for both single-cell and standard (multicell) assembly, and demonstrate that it improves on the recently released E+V-SC assembler (specialized for single-cell data) and on popular assemblers Velvet and SoapDeNovo (for multicell data). SPAdes generates single-cell assemblies, providing information about genomes of uncultivatable bacteria that vastly exceeds what may be obtained via traditional metagenomics studies. SPAdes is available online ( http://bioinf.spbau.ru/spades ). It is distributed as open source software.
10,124 citations
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9,185 citations
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TL;DR: Two important future research directions are indicated and summarized, based on results published in the literature: the development of composite and nanostructured ES materials to overcome the major challenge posed by the low energy density.
Abstract: In this critical review, metal oxides-based materials for electrochemical supercapacitor (ES) electrodes are reviewed in detail together with a brief review of carbon materials and conducting polymers. Their advantages, disadvantages, and performance in ES electrodes are discussed through extensive analysis of the literature, and new trends in material development are also reviewed. Two important future research directions are indicated and summarized, based on results published in the literature: the development of composite and nanostructured ES materials to overcome the major challenge posed by the low energy density of ES (476 references).
7,642 citations
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TL;DR: Some of the major results in random graphs and some of the more challenging open problems are reviewed, including those related to the WWW.
Abstract: We will review some of the major results in random graphs and some of the more challenging open problems. We will cover algorithmic and structural questions. We will touch on newer models, including those related to the WWW.
7,116 citations