Peng Xu

TL;DR: In this article, the authors derived an analytical expression for the permeability in homogeneous porous media based on the fractal characters of porous media and capillary model, which is expressed as a function of fractal dimensions, porosity and maximum pore size.

TL;DR: A draft genome of domesticated C. carpio (strain Songpu) is presented, whose current assembly contains 52,610 protein-coding genes and approximately 92.3% coverage of its paleotetraploidized genome (2n = 100).

TL;DR: A genetically encoded metabolic switch that enables dynamic regulation of fatty acids (FA) biosynthesis in Escherichia coli was reported, able to dynamically compensate the critical enzymes involved in the supply and consumption of malonyl-CoA and efficiently redirect carbon flux toward FA biosynthesis.

TL;DR: A modular engineering approach was systematically removed metabolic pathway bottlenecks and led to significant titre improvements in a multi-gene fatty acid metabolic pathway to demonstrate a generalized approach to engineering cell factories for valuable metabolites production.

TL;DR: Estimating the mechanistic details of the lipogenic phenotype, particularly the cellular compartmentalization of distinct metabolic pathways, fatty acid synthase structure, activating free fatty acids to acyl-CoAs, and decoupling nitrogen starvation from lipogenesis, allowed us to efficiently produce fatty acid ethyl esters, fatty alkanes, medium chain-length fatty acids, fatty alcohols, and triacylglycerides.