P
Per-Henrik Edqvist
Researcher at Uppsala University
Publications - 63
Citations - 14113
Per-Henrik Edqvist is an academic researcher from Uppsala University. The author has contributed to research in topics: Cancer & Glioma. The author has an hindex of 24, co-authored 58 publications receiving 10035 citations. Previous affiliations of Per-Henrik Edqvist include Science for Life Laboratory.
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Tissue-based map of the human proteome
Mathias Uhlén,Mathias Uhlén,Linn Fagerberg,Björn M. Hallström,Cecilia Lindskog,Per Oksvold,Adil Mardinoglu,Åsa Sivertsson,Caroline Kampf,Evelina Sjöstedt,Evelina Sjöstedt,Anna Asplund,IngMarie Olsson,Karolina Edlund,Emma Lundberg,Sanjay Navani,Cristina Al-Khalili Szigyarto,Jacob Odeberg,Dijana Djureinovic,Jenny Ottosson Takanen,Sophia Hober,Tove Alm,Per-Henrik Edqvist,Holger Berling,Hanna Tegel,Jan Mulder,Johan Rockberg,Peter Nilsson,Jochen M. Schwenk,Marica Hamsten,Kalle von Feilitzen,Mattias Forsberg,Lukas Persson,Fredric Johansson,Martin Zwahlen,Gunnar von Heijne,Jens Nielsen,Jens Nielsen,Fredrik Pontén +38 more
TL;DR: In this paper, a map of the human tissue proteome based on an integrated omics approach that involves quantitative transcriptomics at the tissue and organ level, combined with tissue microarray-based immunohistochemistry, to achieve spatial localization of proteins down to the single-cell level.
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A pathology atlas of the human cancer transcriptome
Mathias Uhlén,Mathias Uhlén,Cheng Zhang,Sunjae Lee,Evelina Sjöstedt,Evelina Sjöstedt,Linn Fagerberg,Gholamreza Bidkhori,Rui Benfeitas,Muhammad Arif,Zhengtao Liu,Fredrik Edfors,Kemal Sanli,Kalle von Feilitzen,Per Oksvold,Emma Lundberg,Sophia Hober,Peter Nilsson,Johanna Sofia Margareta Mattsson,Jochen M. Schwenk,Hans Brunnström,Bengt Glimelius,Tobias Sjöblom,Per-Henrik Edqvist,Dijana Djureinovic,Patrick Micke,Cecilia Lindskog,Adil Mardinoglu,Adil Mardinoglu,Fredrik Pontén +29 more
TL;DR: A Human Pathology Atlas has been created as part of the Human Protein Atlas program to explore the prognostic role of each protein-coding gene in 17 different cancers, and reveals that gene expression of individual tumors within a particular cancer varied considerably and could exceed the variation observed between distinct cancer types.
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The Human Protein Atlas as a proteomic resource for biomarker discovery
TL;DR: The Human Protein Atlas as a proteomic resource for biomarker discovery and its applications in medicine and drug discovery are reviewed.
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Antibodies for profiling the human proteome-The Human Protein Atlas as a resource for cancer research.
TL;DR: An update on the progress of the Human Protein Atlas is presented, with an emphasis on strategies for validating immunohistochemistry‐basedprotein expression patterns and on the possibilities to extend the map of protein expression patterns for cancer research projects.
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STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
Cristina Peña,María Virtudes Céspedes,Maja Bradic Lindh,Sara Kiflemariam,Artur Mezheyeuski,Per-Henrik Edqvist,Christina Hägglöf,Helgi Birgisson,Linda Bojmar,Karin Jirström,Per Sandström,Eleonor Olsson,Srinivas Veerla,Alberto Gallardo,Tobias Sjöblom,Andy C.-M. Chang,Roger R. Reddel,Ramon Mangues,Martin Augsten,Arne Östman +19 more
TL;DR: The identification of the secreted glycoprotein stanniocalcin-1 (STC1) as a mediator of metastasis by PDGF receptor function in the setting of colorectal cancer is reported, revealing a mechanistic basis for understanding the contribution of PDGF-activated CAFs to cancer metastasis.