Author
Perry M. Elliott
Other affiliations: University College London Hospitals NHS Foundation Trust, Tufts Medical Center, Imperial College London ...read more
Bio: Perry M. Elliott is an academic researcher from University College London. The author has contributed to research in topics: Hypertrophic cardiomyopathy & Cardiomyopathy. The author has an hindex of 107, co-authored 560 publications receiving 65814 citations. Previous affiliations of Perry M. Elliott include University College London Hospitals NHS Foundation Trust & Tufts Medical Center.
Papers published on a yearly basis
Papers
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TL;DR: Authors/Task Force Members: Piotr Ponikowski* (Chairperson) (Poland), Adriaan A. Voors* (Co-Chair person) (The Netherlands), Stefan D. Anker (Germany), Héctor Bueno (Spain), John G. F. Cleland (UK), Andrew J. S. Coats (UK)
13,400 citations
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TL;DR: The objective of this study was to establish a baseline level of confidence that the once-in-a-lifetime implantation trial—Reduce Inappropriate Therapy protocol can be trusted to provide safe and effective treatment for cardiac arrhythmia and stroke-like episodes.
Abstract: 2D
: two-dimensional
99mTc-DPD
: 99mTechnetium-3,3-diphosphono- 1,2-propanodi-carboxylic acid
ACE
: angiotensin-converting enzyme
AF
: atrial fibrillation
AL
: amyloid light chain
AR
: aortic regurgitation
ARB
: angiotensin receptor blocker
ATTR
: amyloidosis-transthyretin type
AV
: atrioventricular
BiVAD
: biventricular assist device
BNP
: brain natriuretic peptide
BPM
: Beats per minute
CCS
: Canadian Cardiovascular Society
CFC
: cardiofacialcutaneous
CHA2DS2-VASc
: Congestive Heart failure, hypertension, Age ≥75 (doubled), Diabetes, Stroke (doubled), Vascular disease, Age 65–74, and Sex (female)
CMR
: cardiac magnetic resonance
CRT
: cardiac resynchronization therapy
CRT-D
: cardiac resynchronization therapy-defibrillator
CRT-P
: Cardiac resynchronization therapy with a pacemaker
CT
: computed tomography
DC
: direct current
DNA
: deoxyribonucleic acid
E/A
: ratio of mitral peak velocity of early filling (E) to mitral peak velocity of late filling (A)
E/e’
: ratio of early transmitral flow velocity (E) to early mitral annulus velocity (e’)
EACTS
: European Association for Cardio-Thoracic Surgery
ECG
: electrocardiogram
EF
: ejection fraction
EPS
: electrophysiological study
ESC
: European Society of Cardiology
FDA
: (US) Food and Drug Administration
FHL1
: four and a half LIM domains 1
HAS-BLED
: hypertension, abnormal renal/liver function, stroke, bleeding history or predisposition, labile INR, elderly (>65 years), drugs/alcohol concomitantly
HCM
: hypertrophic cardiomyopathy
hs-cTnT
: high sensitivity cardiac troponin T
HTS
: high throughput sequencing
ICD
: implantable cardioverter defibrillator
ILR
: implantable loop recorder
INR
: international normalized ratio
IUD
: intrauterine device
LA
: left atrium
LAMP-2
: lysosome-associated membrane protein 2
LBBB
: left bundle branch block
LEOPARD
: Lentigines, ECG abnormalities, Ocular hypertelorism, Pulmonary stenosis, Abnormal genitalia, Retardation of growth, and sensory-neural Deafness
LGE
: late gadolinium enhancement
LV
: left ventricular
LVAD
: left ventricular assist device
LVH
: left ventricular hypertrophy
LVOTO
: left ventricular outlow tract obstruction
MADIT-RIT
: Multicenter Automatic Defibrillator Implantation Trial—Reduce Inappropriate Therapy
MAPK
: mitogen activated protein kinase
MELAS
: mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes
MERFF
: myoclonic epilepsy with ragged red fibres
MRA
: mineralocorticoid receptor antagonist
MYBPC3
: myosin-binding protein C, cardiac-type
MYH7
: myosin-7 (s-myosin heavy chain)
MYL3
: myosin light chain 3
NOAC
: new oral anticoagulants
NSVT
: non-sustained ventricular tachycardia
NT-proBNP
: N-terminal pro brain natriuretic peptide
NYHA
: New York Heart Association
OAC
: oral anticoagulants
o.d.
: omni die (every day)
PC-CMR
: phase contrast cardiac magnetic resonance
PDE5
: phosphodiesterase type 5
PET
: positron emission tomography
PRKAG2
: gamma-2 sub-unit of the adenosine monophosphate-activated protein kinase
RAAS
: renin angiotensin aldosterone system
RV
: right ventricular
SAM
: systolic anterior motion
SCD
: sudden cardiac death
SAA
: septal alcohol ablation
S-ICD™
: Subcutaneous lead implantable cardioverter defibrillator
SPECT
: single photon emission computed tomography
SSFP
: steady-state free precession
SVT
: supraventricular tachycardia
TOE
: transoesophageal echocardiography
TNNI3
: troponin I, cardiac muscle
TNNT2
: troponin T, cardiac muscle
TPM1
: tropomyosin alpha-1 chain
TTE
: transthoracic echocardiography
TTR
: transthyretin
VF
: ventricular fibrillation
VKA
: vitamin K antagonist
VT
: ventricular tachycardia
WHO
: World Health Organization
Guidelines summarize and evaluate all available evidence at the time of the writing process, on a particular issue with the aim of assisting health professionals in selecting the best management strategies for an individual patient, with a given condition, taking into account the impact on outcome, as well as the risk-benefit-ratio of particular diagnostic or therapeutic means. Guidelines and recommendations should help the health professionals to make decisions in their daily practice. However, the final decisions concerning an individual patient must be made by the responsible health professional(s) in consultation with the patient and caregiver as appropriate.
A great number of Guidelines have been issued in recent years by the European Society of Cardiology (ESC) as well as by other societies and organisations. Because of the impact on clinical practice, quality criteria for the development of guidelines have been established in order to make all decisions transparent to the user. The recommendations for formulating and issuing ESC Guidelines can be found on the ESC website (http://www.escardio.org/guidelines-surveys/esc-guidelines/about/Pages/rules-writing.aspx). ESC Guidelines represent the official position of the ESC on a given topic and are regularly updated.
Members of this Task Force were selected by the ESC to represent professionals involved with the medical care of patients with this pathology. Selected experts in the field undertook a comprehensive review of the published evidence for management (including diagnosis, treatment, prevention and rehabilitation) of a given condition according to ESC Committee for Practice Guidelines (CPG) policy. A critical evaluation of diagnostic and therapeutic procedures was performed including assessment of the risk-benefit-ratio. Estimates of expected health outcomes for larger populations were included, where data exist. The level of evidence and the strength of recommendation of particular management options were weighed and graded according to predefined scales, as outlined in Tables 1 and 2 .
The experts of …
3,276 citations
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3,225 citations
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TL;DR: Authors/Task Force Members: John J. McMurray (Chairperson) (UK), Stamatis Adamopoulos (Greece), Stefan D. Anker (Germany), Angelo Auricchio (Switzerland), Michael Bohm ( Germany), Kenneth Dickstein (Norway), Volkmar Falk (Sw Switzerland), Gerasimos Filippatos (G Greece), Cândida Fonseca (Portugal), Miguel Angel Gomez-Sanchez (Spain).
Abstract: The originally published version of this paper was incorrect. In the table on page 1816, the Class of recommendation and Level of evidence for ‘The patient is pacemaker dependent as a result of AV nodal ablation’ should have read ‘IIa’ and ‘B’ respectively.
Appendix: six tables ([3][1
2,627 citations
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TL;DR: 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy : The Task Force on cardiac paced and resynchronized therapy of the European Society of Cardiology developed in collaboration with the European Heart Rhythm Association.
Abstract: ### Abbreviations
1st AV
: First-degree atrioventricular block
AF
: atrial fibrillation
AT
: atrial tachyarrhythmia
ATP
: Anti-tachycardia pacing
AV
: atrioventricular
BBB
: bundle branch block
CHF
: congestive heart failure
CI
: confidence interval
CPG
: Committee for Practice Guidelines
CRT
: cardiac resynchronization therapy
CRT-D
: cardiac resynchronization therapy and defibrillator
CRT-P
: cardiac resynchronization therapy and pacemaker
ECG
: electrocardiogram
EDMD
: Emery-Dreifuss muscular dystrophy
EF
: ejection fraction
EPS
: electrophysiological study
ESC
: European Society of Cardiology
HCM
: hypertrophic cardiomyopathy
HF
: heart failure
HR
: hazard ratio
HV
: His-ventricular
ICD
: implantable cardioverter defibrillator
ILR
: implantable loop recorder
IVCD
: intraventricular conduction delay
LBBB
: left bundle branch block
LQTS
: long QT syndrome
LV
: left ventricular
LVEF
: left ventricular ejection fraction
LVSD
: left ventricular systolic dysfunction
MR
: mitral regurgitation
MRI
: magnetic resonance imaging
NYHA
: New York Heart Association
PM
: pacemaker
OR
: odds ratio
QALY
: quality-adjusted life year
RBBB
: right bundle branch block
RCT
: randomized controlled trial
RV
: right ventricular
SB
: sinus bradycardia
SNRT
: sinus node recovery time
SR
: sinus rhythm
SSS
: sick sinus syndrome
TAVI
: transcatheter aortic valve implantation
VF
: ventricular fibrillation
VT
: ventricular tachycardia
VV
: interventricular (delay)
### Acronyms of the trials referenced in the recommendations or reported in the tables
ADEPT
: ADvanced Elements of Pacing Randomized Controlled Trial
ADOPT
: Atrial Dynamic Overdrive Pacing Trial
AOPS
: Atrial Overdrive Pacing Study
APAF
: Ablate and Pace in Atrial Fibrillation
ASSERT
: ASymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial
ATTEST
: ATrial Therapy Efficacy and Safety Trial
AVAIL CLS/CRT
: AV Node Ablation with CLS and CRT Pacing Therapies for Treatment of AF trial
B4
: Bradycardia detection in Bundle Branch Block
BELIEVE
: Bi vs. Left Ventricular Pacing: an International Pilot Evaluation on Heart Failure Patients with Ventricular Arrhythmias
BIOPACE
: Biventricular pacing for atrioventricular block to prevent cardiac desynchronization
BLOCK-HF
: Biventricular versus right ventricular pacing in patients with AV block
B-LEFT
: Biventricular versus LEFT Univentricular Pacing with ICD Back-up in Heart Failure Patients
CARE-HF
: CArdiac REsynchronization in Heart Failure
CLEAR
: CLinical Evaluation on Advanced Resynchronization
COMBAT
: COnventional vs. Biventricular Pacing in Heart Failure and Bradyarrhythmia
COMPANION
: COmparison of Medical Therapy, Pacing and Defibrillation in Heart Failure
DANPACE
: DANish Multicenter Randomized Trial on Single Lead Atrial PACing vs. Dual Chamber Pacing in Sick Sinus Syndrome
DECREASE-HF
: The Device Evaluation of CONTAK RENEWAL 2 and EASYTRAK 2: Assessment of Safety and Effectiveness in Heart Failure
FREEDOM
: Optimization Study Using the QuickOpt Method
GREATER-EARTH
: Evaluation of Resynchronization Therapy for Heart Failure in Patients with a QRS Duration GREATER Than 120 ms
LESSER-EARTH
: Evaluation of Resynchronization Therapy for Heart Failure in Patients with a QRS Duration Lower Than 120 ms
HOBIPACE
: HOmburg BIventricular PACing Evaluation
IN-CHF
: Italian Network on Congestive Heart Failure
ISSUE
: International Study on Syncope of Unexplained Etiology
MADIT
: Multicenter Automatic Defibrillator Trial
MIRACLE
: Multicenter InSync RAndomized CLinical Evaluation
MOST
: MOde Selection Trial in Sinus-Node Dysfunction
MUSTIC
: MUltisite STimulation In Cardiomyopathies
OPSITE
: Optimal Pacing SITE
PACE
: Pacing to Avoid Cardiac Enlargement
PAVE
: Left Ventricular-Based Cardiac Stimulation Post AV Nodal Ablation Evaluation
PATH-CHF
: PAcing THerapies in Congestive Heart Failure II Study Group
PIPAF
: Pacing In Prevention of Atrial Fibrillation Study
PIRAT
: Prevention of Immediate Reinitiation of Atrial Tachyarrhythmias
POT
: Prevention Or Termination Study
PREVENT-HF
: PREventing VENTricular Dysfunction in Pacemaker Patients Without Advanced Heart Failure
PROSPECT
: PRedictors Of Response to Cardiac Resynchronization Therapy
RAFT
: Resynchronization–Defibrillation for Ambulatory Heart Failure Trial
RethinQ
: Cardiac REsynchronization THerapy IN Patients with Heart Failure and Narrow QRS
REVERSE
: REsynchronization reVErses Remodelling in Systolic left vEntricular dysfunction
SAFARI
: Study of Atrial Fibrillation Reduction
SCD HeFT
: Sudden Cardiac Death in Heart Failure Trial
SMART-AV
: The SMARTDelay Determined AV Optimization: a Comparison with Other AV Delay Methods Used in Cardiac Resynchronization Therapy
SYDIT
: The SYncope DIagnosis and Treatment
SYNPACE
: Vasovagal SYNcope and PACing
TARGET
: TARgeted Left Ventricular Lead Placement to Guide Cardiac Resynchronization Therapy
THEOPACE
: Effects of Oral THEOphylline and of Permanent PACEmaker on the Symptoms and Complications of Sick Sinus Syndrome
VASIS-PM
: VAsovagal Syncope International Study on PaceMaker therapy
V-HeFT
: Vasodilator in HEart Failure Trial
VPSII
: Second Vasovagal Pacemaker Study (VPS II)
Additional references are mentioned with ‘w’ in the main text and can be found on the online addenda along with 5 figures (1, 6, 7, 9, 11, 12) and 10 tables (3, 4, 5, 9, 11, 12, 19, 21, 22, 23). They are available on the ESC website only at http://www.escardio.org/guidelines-surveys/esc-guidelines/Pages/cardiac-pacing-and-cardiac-resynchronisation-therapy.aspx
Guidelines summarize and evaluate all available evidence, at the time of the writing process, on a …
2,474 citations
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28,685 citations
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TL;DR: Authors/Task Force Members: Piotr Ponikowski* (Chairperson) (Poland), Adriaan A. Voors* (Co-Chair person) (The Netherlands), Stefan D. Anker (Germany), Héctor Bueno (Spain), John G. F. Cleland (UK), Andrew J. S. Coats (UK)
13,400 citations
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TL;DR: In this article, Anderson et al. proposed a new FAHA Chair, Jeffrey L. Anderson, MD, FACC, FAHA, Chair-Elect, Alice K. Jacobs et al., this article and Biykem Bozkurt.
11,386 citations
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9,185 citations