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Peter A. Mossey
Researcher at University of Dundee
Publications - 160
Citations - 8216
Peter A. Mossey is an academic researcher from University of Dundee. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 149 publications receiving 7045 citations. Previous affiliations of Peter A. Mossey include King Abdulaziz University & World Health Organization.
Papers
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Journal ArticleDOI
Cleft lip and palate
TL;DR: Prevention is the ultimate objective for clefts of the lip and palate, and a prerequisite of this aim is to elucidate causes of the disorders.
Journal ArticleDOI
Global Economic Impact of Dental Diseases
TL;DR: The findings suggest that the global economic impact of dental diseases amounted to US$442 billion in 2010, which may imply substantial economic benefits not only in terms of reduced treatment costs but also because of fewer productivity losses in the labor market.
Journal ArticleDOI
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24
Stefanie Birnbaum,Stefanie Birnbaum,Kerstin U. Ludwig,Heiko Reutter,Stefan Herms,Michael Steffens,Michele Rubini,Carlotta Baluardo,Melissa Ferrian,Nilma Almeida de Assis,Margrieta A. Alblas,Sandra Barth,Jan Freudenberg,Carola Lauster,Gül Schmidt,Martin Scheer,Bert Braumann,Stefaan J. Bergé,Rudolf H. Reich,Franziska Schiefke,Alexander Hemprich,Simone Pötzsch,Régine P.M. Steegers-Theunissen,Bernd Pötzsch,Susanne Moebus,Bernhard Horsthemke,Franz-Josef Kramer,Thomas F. Wienker,Peter A. Mossey,Peter Propping,Sven Cichon,Per Hoffmann,Michael Knapp,Markus M. Nöthen,Elisabeth Mangold +34 more
TL;DR: A 640-kb region at chromosome 8q24.21 was found to contain multiple markers with highly significant evidence for association with the cleft phenotype, including three markers that reached genome-wide significance.
Book ChapterDOI
Epidemiology of oral clefts 2012: an international perspective.
TL;DR: This chapter is set out in three parts and seeks to address all three of the above areas: Birth defects in general and orofacial clefting in particular, access to care and evidence base.
Journal ArticleDOI
Disruption of an AP-2 alpha binding site in an IRF6 enhancer is associated with cleft lip
Fedik Rahimov,Mary L. Marazita,Axel Visel,Margaret E. Cooper,Michael J. Hitchler,Michele Rubini,Frederick E. Domann,Manika Govil,Kaare Christensen,Camille Bille,Mads Melbye,Astanand Jugessur,Rolv T. Lie,Allen J. Wilcox,David R. FitzPatrick,Eric D. Green,Peter A. Mossey,Julian Little,Régine P.M. Steegers-Theunissen,Len A. Pennacchio,Brian C. Schutte,Jeffrey C. Murray +21 more
TL;DR: These findings place IRF6 and AP-2α in the same developmental pathway and identify a high-frequency variant in a regulatory element contributing substantially to a common, complex disorder.