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Peter Cloetens

Bio: Peter Cloetens is an academic researcher from European Synchrotron Radiation Facility. The author has contributed to research in topics: Synchrotron radiation & Tomography. The author has an hindex of 68, co-authored 377 publications receiving 17080 citations. Previous affiliations of Peter Cloetens include University of Antwerp & Helmholtz-Zentrum Berlin.


Papers
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Journal ArticleDOI
TL;DR: Using a high-efficiency grating interferometer for hard X rays (10-30 keV) and a phase-stepping technique, separate radiographs of the phase and absorption profiles of bulk samples can be obtained from a single set of measurements.
Abstract: Using a high-efficiency grating interferometer for hard X rays (10-30 keV) and a phase-stepping technique, separate radiographs of the phase and absorption profiles of bulk samples can be obtained from a single set of measurements. Tomographic reconstruction yields quantitative three-dimensional maps of the X-ray refractive index, with a spatial resolution down to a few microns. The method is mechanically robust, requires little spatial coherence and monochromaticity, and can be scaled up to large fields of view, with a detector of correspondingly moderate spatial resolution. These are important prerequisites for use with laboratory X-ray sources.

1,264 citations

Journal ArticleDOI
TL;DR: In this article, a holographic reconstruction procedure combining images taken at different distances from the specimen was developed, which results in quantitative phase mapping and, through association with threedimensional reconstruction, in holotomography, the complete three-dimensional mapping of the density in a sample.
Abstract: Because the refractive index for hard x rays is slightly different from unity, the optical phase of a beam is affected by transmission through an object. Phase images can be obtained with extreme instrumental simplicity by simple propagation provided the beam is coherent. But, unlike absorption, the phase is not simply related to image brightness. A holographic reconstruction procedure combining images taken at different distances from the specimen was developed. It results in quantitative phase mapping and, through association with three-dimensional reconstruction, in holotomography, the complete three-dimensional mapping of the density in a sample. This tool in the characterization of materials at the micrometer scale is uniquely suited to samples with low absorption contrast and radiation-sensitive systems.

903 citations

Journal ArticleDOI
TL;DR: In this article, it is shown that phase objects can lead to spurious contrast in x-ray diffraction images (topographs) of crystals, which can be eliminated through random phase plates, which provide an effective way of tailoring the angular size of the source.
Abstract: Phase objects are readily imaged through Fresnel diffraction in the hard x-ray beams of third-generation synchrotron radiation sources such as the ESRF, due essentially to the very small angular size of the source. Phase objects can lead to spurious contrast in x-ray diffraction images (topographs) of crystals. It is shown that this contrast can be eliminated through random phase plates, which provide an effective way of tailoring the angular size of the source. The possibilities of this very simple technique for imaging phase objects in the hard x-ray range are explored experimentally and discussed. They appear very promising, as shown in particular by the example of a piece of human vertebra, and could be extended to phase tomography.

782 citations

Journal ArticleDOI
TL;DR: In this paper, phase jumps related to the interface between the matrix and the reinforcing phases of the composites are detected even when these phases show very similar x-ray attenuation, illustrating the potential of the technique for assessing damage in materials with improved resolution and sensitivity.
Abstract: The novel possibilities of phase feature detection in radiography at a third generation synchrotron radiation source are used to image, both in projection and in computed tomography, a cracked silicon single crystal and metal matrix composites strained in tension. Through an instrumentally very simple technique, based on Fresnel diffraction, phase jumps related to the interface between the matrix and the reinforcing phases of the composites are detected even when these phases show very similar x-ray attenuation. Strain-induced cracks with openings below the micrometer range are also visible through the phase modulation they introduce, illustrating the potential of the technique for assessing damage in materials with improved resolution and sensitivity.

516 citations

Journal ArticleDOI
TL;DR: In this paper, the authors present selected results obtained in various investigations of metallic materials such as superplastic deformation, materials in the semi-solid state and metallic foams.
Abstract: X-ray tomography is a non-destructive technique which provides 3D information of materials. It is consequently very attractive in Materials Science since the relation between macroscopic properties and the micro-structure of a material is very frequently required. The aim of this paper is to present selected results obtained in various investigations of metallic materials such as superplastic deformation, materials in the semi-solid state and metallic foams. Depending on the studied features, several tomography analysis modes were used: conventional absorption mode, phase contrast and holotomography, a new technique, which provides the 3D distribution of the electron density in the bulk of the material. Furthermore micro-tomography enables one to perform in situ experiments either by using a mechanical test machine or a furnace.

454 citations


Cited by
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Journal ArticleDOI

[...]

08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations

Journal ArticleDOI
01 Apr 1988-Nature
TL;DR: In this paper, a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) is presented.
Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

9,929 citations

Proceedings Article
01 Jan 1999
TL;DR: In this paper, the authors describe photonic crystals as the analogy between electron waves in crystals and the light waves in artificial periodic dielectric structures, and the interest in periodic structures has been stimulated by the fast development of semiconductor technology that now allows the fabrication of artificial structures, whose period is comparable with the wavelength of light in the visible and infrared ranges.
Abstract: The term photonic crystals appears because of the analogy between electron waves in crystals and the light waves in artificial periodic dielectric structures. During the recent years the investigation of one-, two-and three-dimensional periodic structures has attracted a widespread attention of the world optics community because of great potentiality of such structures in advanced applied optical fields. The interest in periodic structures has been stimulated by the fast development of semiconductor technology that now allows the fabrication of artificial structures, whose period is comparable with the wavelength of light in the visible and infrared ranges.

2,722 citations

Journal ArticleDOI
TL;DR: In this article, a setup consisting of three transmission gratings can efficiently yield quantitative differential phase-contrast images with conventional X-ray tubes, which can be scaled up to large fields of view.
Abstract: X-ray radiographic absorption imaging is an invaluable tool in medical diagnostics and materials science. For biological tissue samples, polymers or fibre composites, however, the use of conventional X-ray radiography is limited due to their weak absorption. This is resolved at highly brilliant X-ray synchrotron or micro-focus sources by using phase-sensitive imaging methods to improve the contrast1,2. However, the requirements of the illuminating radiation mean that hard-X-ray phase-sensitive imaging has until now been impractical with more readily available X-ray sources, such as X-ray tubes. In this letter, we report how a setup consisting of three transmission gratings can efficiently yield quantitative differential phase-contrast images with conventional X-ray tubes. In contrast with existing techniques, the method requires no spatial or temporal coherence, is mechanically robust, and can be scaled up to large fields of view. Our method provides all the benefits of contrast-enhanced phase-sensitive imaging, but is also fully compatible with conventional absorption radiography. It is applicable to X-ray medical imaging, industrial non-destructive testing, and to other low-brilliance radiation, such as neutrons or atoms.

1,789 citations