P
Peter Koopman
Researcher at University of Queensland
Publications - 315
Citations - 30220
Peter Koopman is an academic researcher from University of Queensland. The author has contributed to research in topics: Testis determining factor & Gene. The author has an hindex of 81, co-authored 309 publications receiving 28015 citations. Previous affiliations of Peter Koopman include National Institute for Medical Research & University of Newcastle.
Papers
More filters
Journal ArticleDOI
Male development of chromosomally female mice transgenic for Sry
TL;DR: It is shown that Sry on a 14-kilobase genomic DNA fragment is sufficient to induce testis differentiation and subsequent male development when introduced into chromosomally female mouse embryos.
Journal ArticleDOI
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
John Gubbay,Jérôme Collignon,Peter Koopman,Blanche Capel,Androulla Economou,Andrea Münsterberg,Nigel Vivian,Peter N. Goodfellow,Robin Lovell-Badge +8 more
TL;DR: A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination.
Journal ArticleDOI
Circular transcripts of the testis-determining gene Sry in adult mouse testis
Blanche Capel,Amanda Swain,Silvia K. Nicolis,Adam Hacker,Michael A. Walter,Peter Koopman,Peter N. Goodfellow,Robin Lovell-Badge +7 more
TL;DR: It is suggested that the circles arise from normal splicing processes as a consequence of the unusual genomic structure surrounding the Sry locus in the mouse.
Journal ArticleDOI
Retinoid Signaling Determines Germ Cell Fate in Mice
Josephine Bowles,D. Knight,Christopher A. Smith,Dagmar Wilhelm,Joy M. Richman,Joy M. Richman,Satoru Mamiya,Kenta Yashiro,Kallayanee Chawengsaksophak,Megan J. Wilson,Janet Rossant,Hiroshi Hamada,Peter Koopman +12 more
TL;DR: It is found that retinoic acid, produced by mesonephroi of both sexes, causes germ cells in the ovary to enter meiosis and inititate oogenesis, and precise regulation of retinoid levels during fetal gonad development provides the molecular control mechanism that specifies germ cell fate.
Journal ArticleDOI
Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators.
TL;DR: A robust phylogeny of SOX genes is proposed that reflects their evolutionary history in metazoans and finds support for subdivision of the family into groups A-H, as has been suggested in some previous studies, and for the assignment of two new groups, I and J.