P
Péter Nagy
Researcher at University of Debrecen
Publications - 196
Citations - 6518
Péter Nagy is an academic researcher from University of Debrecen. The author has contributed to research in topics: Sulfide & Hydrogen sulfide. The author has an hindex of 35, co-authored 175 publications receiving 5036 citations. Previous affiliations of Péter Nagy include University of Oklahoma & University of Otago.
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Journal ArticleDOI
Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods.
Tamás Baranyai,Kata Herczeg,Zsófia Onódi,István Voszka,Károly Módos,Nikolett Marton,György Nagy,Imre Mäger,Imre Mäger,Matthew J.A. Wood,Samir El Andaloussi,Samir El Andaloussi,Zoltán Pálinkás,Vikas Kumar,Péter Nagy,Ágnes Kittel,Edit I. Buzás,Péter Ferdinandy,Zoltán Giricz +18 more
TL;DR: It is shown that it is feasible to isolate exosomes from blood plasma by SEC without significant albumin contamination albeit with low vesicle yield.
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Polysulfides Link H2S to Protein Thiol Oxidation
Romy Greiner,Zoltán Pálinkás,Katrin Bäsell,Dörte Becher,Haike Antelmann,Péter Nagy,Tobias P. Dick +6 more
TL;DR: This study suggests that the effects that have been attributed to H2S in previous reports may in fact have been mediated by polysulfides, and supports the notion that sulfane sulfur rather than sulfide is the actual in vivo agent of H 2S signaling.
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Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility.
Katsuhiko Ono,Takaaki Akaike,Tomohiro Sawa,Yoshito Kumagai,David A. Wink,Dean J. Tantillo,Adrian J. Hobbs,Péter Nagy,Ming Xian,Joseph Lin,Jon M. Fukuto +10 more
TL;DR: The basic chemical biology of H2S as well as other related or derived species is discussed and reviewed, and this review particularly focuses on the per- and polysulfides which are likely in equilibrium with free H 2S and which may be important biological effectors themselves.
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Kinetics and mechanisms of thiol-disulfide exchange covering direct substitution and thiol oxidation-mediated pathways.
TL;DR: This review is focused on the kinetics and mechanisms of thiol-disulfide substitution and redox reactions, and summarizes the challenges and advances associated with kinetic investigations in small molecular and enzymatic systems from a rigorous chemical perspective using biological examples.
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Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics
Takaaki Akaike,Tomoaki Ida,Fan Yan Wei,Motohiro Nishida,Motohiro Nishida,Yoshito Kumagai,Md. Morshedul Alam,Hideshi Ihara,Tomohiro Sawa,Tetsuro Matsunaga,Shingo Kasamatsu,Akiyuki Nishimura,Masanobu Morita,Kazuhito Tomizawa,Akira Nishimura,Satoshi Watanabe,Kenji Inaba,Hiroshi Shima,Nobuhiro Tanuma,Minkyung Jung,Shigemoto Fujii,Yasuo Watanabe,Masaki Ohmuraya,Péter Nagy,Martin Feelisch,Jon M. Fukuto,Hozumi Motohashi +26 more
TL;DR: Targeted disruption of the genes encoding mitochondrial CARSs in mice and human cells shows that CARS have a crucial role in endogenous CysSSH production and suggests that these enzymes serve as the principal cysteine persulfide synthases in vivo.