P
Peter R. Jungblut
Researcher at Max Planck Society
Publications - 139
Citations - 10853
Peter R. Jungblut is an academic researcher from Max Planck Society. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 55, co-authored 137 publications receiving 10168 citations.
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Journal ArticleDOI
Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans
Constantin F. Urban,David Ermert,Monika Schmid,Ulrike Abu-Abed,Christian Goosmann,Wolfgang Nacken,Volker Brinkmann,Peter R. Jungblut,Arturo Zychlinsky +8 more
TL;DR: The present investigations confirmed the antifungal activity of calprotectin in vitro and demonstrated that it contributes to effective host defense against C. albicans in vivo.
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Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42.
Xiao-Hua Chen,Alexandra Koumoutsi,Romy Scholz,Andreas Eisenreich,Kathrin Schneider,Isabelle Heinemeyer,Burkhard Morgenstern,Björn Voss,Wolfgang R. Hess,Oleg N. Reva,Helmut Junge,Birgit Voigt,Peter R. Jungblut,Joachim Vater,Roderich D. Süssmuth,Heiko Liesegang,Axel Strittmatter,Gerhard Gottschalk,Rainer Borriss +18 more
TL;DR: The B. amyloliquefaciens FZB42 genome reveals an unexpected potential to produce secondary metabolites, including the polyketides bacillaene and difficidin, and identifies four giant gene clusters absent in B. subtilis 168.
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Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus.
Steffen Backert,Elke Ziska,Volker Brinkmann,Ursula Zimny-Arndt,Alain Fauconnier,Peter R. Jungblut,Michael Naumann,Thomas F. Meyer +7 more
TL;DR: Evidence that the H. pylori protein encoded by the cytotoxin‐associated gene A (cagA) is translocated and phosphorylated in infected epithelial cells supports the view that H.pylori actively translocates virulence determinants, including CagA, which could be involved in the development of a variety of gastric disease.
Journal ArticleDOI
Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu,Haiping Zhang,Xiangyang Wu,Dapeng Ma,Juehui Wu,Lin Wang,Yan Jiang,Yiyan Fei,Chenggang Zhu,Rong Tan,Peter R. Jungblut,Gang Pei,Anca Dorhoi,Anca Dorhoi,Qiaoling Yan,Fan Zhang,Ruijuan Zheng,Siyu Liu,Haijiao Liang,Zhonghua Liu,Hua Yang,Jianxia Chen,Peng Wang,Tianqi Tang,Wenxia Peng,Zhangsen Hu,Zhu Xu,Xiaochen Huang,Jie Wang,Haohao Li,Yilong Zhou,Feng Liu,Dapeng Yan,Stefan H. E. Kaufmann,Chang Chen,Zhiyong Mao,Baoxue Ge +36 more
TL;DR: It is concluded that nuclear cGAS suppresses homologous-recombination-mediated repair and promotes tumour growth, and that cGas therefore represents a potential target for cancer prevention and therapy.
Journal ArticleDOI
Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens
Peter R. Jungblut,Ulrich E. Schaible,Hans-Joachim Mollenkopf,Ursula Zimny-Arndt,Bärbel Raupach,Jens Mattow,Petr Halada,Stephanie Lamer,Kristine Hagens,Stefan H. E. Kaufmann +9 more
TL;DR: It is to be hoped that the availability of the mycobacterial proteome will facilitate the design of novel measures for prevention and therapy of one of the great health threats, tuberculosis.