P
Peter S. LaViolette
Researcher at Medical College of Wisconsin
Publications - 105
Citations - 7031
Peter S. LaViolette is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 34, co-authored 79 publications receiving 6032 citations. Previous affiliations of Peter S. LaViolette include Milwaukee School of Engineering & Cleveland Clinic.
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Journal ArticleDOI
Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia
Susan Whitfield-Gabrieli,Heidi W. Thermenos,Snezana Milanovic,Ming T. Tsuang,Stephen V. Faraone,Robert W. McCarley,Martha E. Shenton,Alan I. Green,Alfonso Nieto-Castanon,Peter S. LaViolette,Joanne Wojcik,John D. E. Gabrieli,Larry J. Seidman +12 more
TL;DR: Among patients, the magnitude of MPFC task suppression negatively correlated with default connectivity, suggesting an association between the hyperactivation and hyperconnectivity in schizophrenia.
Journal ArticleDOI
Amyloid deposition is associated with impaired default network function in older persons without dementia
Reisa A. Sperling,Reisa A. Sperling,Peter S. LaViolette,Kelly O'Keefe,Jacqueline O'Brien,Dorene M. Rentz,Dorene M. Rentz,Maija Pihlajamäki,Gad A. Marshall,Gad A. Marshall,Bradley T. Hyman,Dennis J. Selkoe,Trey Hedden,Randy L. Buckner,J. Alex Becker,Keith A. Johnson,Keith A. Johnson +16 more
TL;DR: It is demonstrated that high levels of amyloid deposition are associated with aberrant default network functional magnetic resonance imaging (fMRI) activity in asymptomatic and minimally impaired older individuals, similar to the pattern of dysfunction reported in AD patients.
Journal ArticleDOI
Functional Alterations in Memory Networks in Early Alzheimer’s Disease
Reisa A. Sperling,Reisa A. Sperling,Bradford C. Dickerson,Maija Pihlajamäki,Maija Pihlajamäki,Patrizia Vannini,Patrizia Vannini,Peter S. LaViolette,Peter S. LaViolette,Ottavio V. Vitolo,Ottavio V. Vitolo,Trey Hedden,J. Alex Becker,Dorene M. Rentz,Dorene M. Rentz,Dennis J. Selkoe,Dennis J. Selkoe,Keith A. Johnson,Keith A. Johnson +18 more
TL;DR: Findings suggest that the pathophysiological process of AD exerts specific deleterious effects on these distributed memory circuits, even prior to clinical manifestations of significant memory impairment.
Journal ArticleDOI
Longitudinal molecular trajectories of diffuse glioma in adults
Floris P. Barthel,Kevin C. Johnson,Frederick S. Varn,Anzhela D. Moskalik,Georgette Tanner,Emre Kocakavuk,Kevin J. Anderson,Olajide Abiola,Kenneth Aldape,Kristin Alfaro,Donát Alpár,Donát Alpár,Samirkumar B. Amin,David M. Ashley,Pratiti Bandopadhayay,Pratiti Bandopadhayay,Jill S. Barnholtz-Sloan,Rameen Beroukhim,Rameen Beroukhim,Christoph Bock,Christoph Bock,Priscilla K. Brastianos,Daniel J. Brat,Andrew R Brodbelt,Alexander F. Bruns,Ketan R. Bulsara,Aruna Chakrabarty,Arnab Chakravarti,Jeffrey H. Chuang,Elizabeth B. Claus,Elizabeth B. Claus,Elizabeth J. Cochran,Jennifer Connelly,Joseph F. Costello,Gaetano Finocchiaro,Michael N. C. Fletcher,Pim J. French,Hui K Gan,Hui K Gan,Mark R. Gilbert,Peter Gould,Matthew R. Grimmer,Antonio Iavarone,Azzam Ismail,Michael D. Jenkinson,Mustafa Khasraw,Hoon Kim,Mathilde C.M. Kouwenhoven,Peter S. LaViolette,Meihong Li,Peter Lichter,Keith L. Ligon,Keith L. Ligon,Allison Lowman,Tathiane M. Malta,Tali Mazor,Kerrie L. McDonald,Annette M. Molinaro,Do-Hyun Nam,Naema Nayyar,Ho Keung Ng,Chew Yee Ngan,Simone P. Niclou,Johanna M. Niers,Houtan Noushmehr,Javad Noorbakhsh,D. Ryan Ormond,Chul-Kee Park,Laila M. Poisson,Raul Rabadan,Raul Rabadan,Bernhard Radlwimmer,Ganesh Rao,Guido Reifenberger,Jason K. Sa,Michael Schuster,Brian L. Shaw,Susan C Short,Peter A. E. Sillevis Smitt,Andrew E. Sloan,Andrew E. Sloan,Marion Smits,Hiromichi Suzuki,Ghazaleh Tabatabai,Erwin G. Van Meir,Colin Watts,Michael Weller,Pieter Wesseling,Bart A. Westerman,Georg Widhalm,Adelheid Woehrer,W. K. Alfred Yung,Gelareh Zadeh,Jason T. Huse,John de Groot,Lucy F. Stead,Roel G.W. Verhaak +96 more
TL;DR: The results suggest that the strongest selective pressures occur during early glioma development and that current therapies shape this evolution in a largely stochastic manner.
Journal ArticleDOI
Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline
Jacqueline O'Brien,Kelly O'Keefe,Peter S. LaViolette,Amy DeLuca,Deborah Blacker,Bradford C. Dickerson,Reisa A. Sperling +6 more
TL;DR: Longitudinal fMRI provides a reliable indicator of brain activation over time, and may prove useful in identifying functional brain changes associated with cognitive decline on the trajectory toward clinical Alzheimer disease.