P
Peter See
Researcher at Singapore Immunology Network
Publications - 12
Citations - 5873
Peter See is an academic researcher from Singapore Immunology Network. The author has contributed to research in topics: Population & MRNA Sequencing. The author has an hindex of 10, co-authored 12 publications receiving 4446 citations.
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Journal ArticleDOI
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux,Florent Ginhoux,Melanie Greter,Marylene Leboeuf,Sayan Nandi,Peter See,Solen Gokhan,Mark F. Mehler,Simon J. Conway,Lai Guan Ng,E. Richard Stanley,Igor M. Samokhvalov,Miriam Merad +12 more
TL;DR: Results identify microglia as an ontogenically distinct population in the mononuclear phagocyte system and have implications for the use of embryonically derived microglial progenitors for the treatment of various brain disorders.
Journal ArticleDOI
Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Svetoslav Chakarov,Hwee Ying Lim,Leonard Tan,Sheau Yng Lim,Peter See,Josephine Lum,Xiao Meng Zhang,Shihui Foo,Satoshi Nakamizo,Kaibo Duan,Wan Ting Kong,Rebecca Gentek,Akhila Balachander,Daniel Carbajo,Camille Bleriot,Benoit Malleret,Benoit Malleret,John Kit Chung Tam,Sonia Baig,Muhammad Shabeer,Sue-Anne Ee Shiow Toh,Andreas Schlitzer,Anis Larbi,Thomas Marichal,Bernard Malissen,Jinmiao Chen,Michael Poidinger,Kenji Kabashima,Kenji Kabashima,Marc Bajénoff,Lai Guan Ng,Veronique Angeli,Florent Ginhoux +32 more
TL;DR: In this article, two independent resident tissue macrophages (RTMs) populations are identified across tissues with specific niche-dependent phenotype and functional programming, and they are slowly replaced by Ly6Chi monocytes.
Journal ArticleDOI
Mapping the human DC lineage through the integration of high-dimensional techniques
Peter See,Charles-Antoine Dutertre,Charles-Antoine Dutertre,Jinmiao Chen,Patrick Günther,Naomi McGovern,Sergio Erdal Irac,Merry Gunawan,Marc Beyer,Marc Beyer,Kristian Händler,Kaibo Duan,Hermi Sumatoh,Nicolas Ruffin,Mabel Jouve,Ester Gea-Mallorquí,Raoul C.M. Hennekam,Tony Kiat Hon Lim,Chan Chung Yip,Ming Wen,Benoit Malleret,Benoit Malleret,Ivy Low,Nurhidaya Binte Shadan,Charlene Foong Shu Fen,Alicia Tay,Josephine Lum,Francesca Zolezzi,Anis Larbi,Michael Poidinger,Jerry Kok Yen Chan,Qingfeng Chen,Laurent Rénia,Muzlifah Haniffa,Philippe Benaroch,Andreas Schlitzer,Andreas Schlitzer,Joachim L. Schultze,Joachim L. Schultze,Evan W. Newell,Florent Ginhoux +40 more
TL;DR: Two unbiased high-dimensional technologies are employed to characterize the human DC lineage from bone marrow to blood and provide new markers that can be used to identify unambiguously pre-DC from pDC, including CD33, CX3CR1, CD2, CD5, and CD327.
Journal Article
Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Svetoslav Chakarov,Hwee Ying Lim,Leonard Tan,Sheau Yng Lim,Peter See,Josephine Lum,Xiao Meng Zhang,Shihui Foo,Satoshi Nakamizo,Kaibo Duan,Wan Ting Kong,Rebecca Gentek,Akhila Balachander,Daniel Carbajo,Camille Bleriot,Benoit Malleret,John Kit Chung Tam,Sonia Baig,Muhammad Shabeer,Sue-Anne Ee Shiow Toh,Andreas Schlitzer,Anis Larbi,Thomas Marichal,Bernard Malissen,Jinmiao Chen,Michael Poidinger,Kenji Kabashima,Marc Bajénoff,Lai Guan Ng,Veronique Angeli,Florent Ginhoux +30 more
TL;DR: Two independent MRTMs populations exist across tissues with specific niche-dependent phenotype and functional programming, and it is shown that monocyte-derived RTMs (MRTMs) are two separate lineages, rather than representing points along a developmental or maturation continuum.
Journal ArticleDOI
Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.
Hwee Ying Lim,Sheau Yng Lim,Chek Kun Tan,Chung Hwee Thiam,Chi Ching Goh,Daniel Carbajo,Samantha Chew,Peter See,Svetoslav Chakarov,Xiao-Nong Wang,Li Hui Lim,Louise A. Johnson,Josephine Lum,Chui Yee Fong,Ariff Bongso,Arijit Biswas,Chern Goh,Maximilien Evrard,Kim Pin Yeo,Ranu Basu,Jun Kit Wang,Yingrou Tan,Rohit Jain,Shweta Tikoo,Cleo Choong,Wolfgang Weninger,Michael Poidinger,Richard E. Stanley,Matthew Collin,Nguan Soon Tan,Nguan Soon Tan,Lai Guan Ng,David A. Jackson,Florent Ginhoux,Veronique Angeli +34 more
TL;DR: It is demonstrated that in the mouse aorta, resident macrophages prevented arterial stiffness and collagen deposition in the steady state and possessed the unique ability to modulate collagen expression in SMCs by matrix metalloproteinase MMP‐9‐dependent proteolysis through engagement of LYVE‐1 with the HA pericellular matrix of SMCs.