Author
Petr Bures
Other affiliations: University of Texas at Austin
Bio: Petr Bures is an academic researcher from Purdue University. The author has contributed to research in topics: Self-healing hydrogels & Radical polymerization. The author has an hindex of 4, co-authored 4 publications receiving 3435 citations. Previous affiliations of Petr Bures include University of Texas at Austin.
Papers
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TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
3,484 citations
TL;DR: Tethering of long PEG chains on PAA hydrogels and their copolymers can be achieved by grafting reactions involving thionyl chloride, followed by PEG grafting, and the ensuing materials exhibit mucoadhesive properties due to enhanced anchoring of the chains with the mucosa.
178 citations
TL;DR: This chapter presents an analysis of the structural and biological properties of polymer networks, both neutral and responsive, and outlines the significance of these properties in biomedical applications.
Abstract: Publisher Summary As biomedical materials are becoming more advanced and sophisticated, advanced techniques of combinatorial chemistry and molecular design are becoming of utmost importance in order to achieve better design and desirable response to the biological environment. In particular, hydrophilic polymer networks have attained new importance in this field, as they are particularly prone to molecular or structural changes. Their structure can be modified by copolymerization to achieve hydrophilicity or hydrophobicity. In addition, the presence of selected functional groups can make these networks responsive to environmental changes. This chapter presents an analysis of the structural and biological properties of polymer networks, both neutral and responsive. It outlines the significance of these properties in biomedical applications. An overview of currently pursued hydrogels technologies is also provided.
33 citations
Patent•
22 Aug 2001
TL;DR: In this article, a cross-linked hydrogel composition in the form of substantially uniform microparticles and a method of preparation therefor is described. But this method is not suitable for the case of water dispersible polyolefin crosslinking agents.
Abstract: The invention relates to a cross-linked hydrogel composition in the form of substantially uniform microparticles and a method of preparation therefor. The hydrogel composition comprises a crosslinked polymer formed by free radical polymerization of olefin monomers comprising a C3-C6 unsaturated carboxylic acid and a water dispersible polyolefin crosslinking agent. The olefin monomers may further comprise a polyalkyleneglycol monoacrylate or momomethacrylate.
21 citations
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TL;DR: This work highlights recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for biomedical and biological applications and shows how such systems' intelligent behavior can be used in sensors, microarrays, and imaging.
Abstract: Hydrophilic polymers are the center of research emphasis in nanotechnology because of their perceived “intelligence”. They can be used as thin films, scaffolds, or nanoparticles in a wide range of biomedical and biological applications. Here we highlight recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for these applications. Natural, biohybrid, and synthetic hydrophilic polymers and hydrogels are analyzed and their thermodynamic responses are discussed. In addition, examples of the use of hydrogels for various therapeutic applications are given. We show how such systems’ intelligent behavior can be used in sensors, microarrays, and imaging. Finally, we outline challenges for the future in integrating hydrogels into biomedical applications.
3,524 citations
TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
2,034 citations
TL;DR: From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.
1,788 citations
TL;DR: Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives and their applications in Nano Science and Bioinspired Science.
Abstract: Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives Xiaoqiang Chen, Tuhin Pradhan, Fang Wang, Jong Seung Kim,* and Juyoung Yoon* Departments of Chemistry and Nano Science and of Bioinspired Science (WCU), Ewha Womans University, Seoul 120-750, Korea State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing University of Technology, Nanjing 210009, China Department of Chemistry, Korea University, Seoul 136-701, Korea
1,719 citations
TL;DR: Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
1,704 citations