P
Petr Nickl
Researcher at Academy of Sciences of the Czech Republic
Publications - 7
Citations - 118
Petr Nickl is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Epitope & Medicine. The author has an hindex of 3, co-authored 4 publications receiving 38 citations.
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Journal ArticleDOI
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
Raoul De Gasparo,Mattia Pedotti,Luca Simonelli,Petr Nickl,Frauke Muecksch,Irene Cassaniti,Elena Percivalle,Julio C. C. Lorenzi,Federica Mazzola,Davide Magrì,Tereza Michalcikova,Jan Haviernik,Václav Hönig,Blanka Mrazkova,Natalie Polakova,Andrea Fortova,Jolana Tureckova,Veronika Iatsiuk,Salvatore Di Girolamo,Martin Palus,Dagmar Zudova,Petr Bednar,Ivana Bukova,Filippo Bianchini,Dora Mehn,Radim Nencka,Petra Straková,Oto Pavlis,Jan Rozman,Sabrina Gioria,Josè Camilla Sammartino,Federica Giardina,Stefano Gaiarsa,Qiang Pan-Hammarström,Christopher O. Barnes,Pamela J. Bjorkman,Luigi Calzolai,Antonio Piralla,Fausto Baldanti,Michel C. Nussenzweig,Michel C. Nussenzweig,Paul D. Bieniasz,Paul D. Bieniasz,Theodora Hatziioannou,Jan Prochazka,Radislav Sedlacek,Davide F. Robbiani,Daniel Ruzek,Luca Varani +48 more
TL;DR: In this article, a bispecific IgG-1-like molecule (CoV-X2) was developed on the basis of C121 and C135, two antibodies derived from donors who had recovered from COVID-193.
Journal ArticleDOI
CRISPR/Cas9 Epigenome Editing Potential for Rare Imprinting Diseases: A Review
TL;DR: This new era of CRISPR epigenome editors could arguably be a game-changer for curing and treating rare IDs by refined activation and silencing of disturbed imprinted gene expression.
Posted ContentDOI
Bispecific antibody prevents SARS-CoV-2 escape and protects mice from disease
Raoul De Gasparo,Mattia Pedotti,Luca Simonelli,Petr Nickl,Frauke Muecksch,Irene Cassaniti,Elena Percivalle,Julio C. C. Lorenzi,Federica Mazzola,Davide Magrì,Tereza Michalcikova,Jan Haviernik,Václav Hönig,Blanka Mrazkova,Natalie Polakova,Andrea Fortova,Jolana Tureckova,Veronika Iatsiuk,Salvatore Di Girolamo,Martin Palus,Dagmar Zudova,Petr Bednar,Ivana Bukova,Filippo Bianchini,Dora Mehn,Radim Nencka,Petra Straková,Oto Pavlis,Jan Rozman,Sabrina Gioria,Josè Camilla Sammartino,Federica Giardina,Stefano Gaiarsa,Qiang Pan Hammarström,Christopher O. Barnes,Pamela J. Bjorkman,Luigi Calzolai,Antonio Piralla,Fausto Baldanti,Michel C. Nussenzweig,Michel C. Nussenzweig,Paul D. Bieniasz,Paul D. Bieniasz,Theodora Hatziioannou,Jan Prochazka,Radislav Sedlacek,Davide F. Robbiani,Daniel Ruzek,Luca Varani +48 more
TL;DR: A bispecific, IgG-1-like molecule based on two antibodies derived from COVID-19 convalescent donors, C121 and C1353, was developed in this paper.
Posted ContentDOI
Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease.
Raoul De Gasparo,Mattia Pedotti,Luca Simonelli,Petr Nickl,Frauke Muecksch,Irene Cassaniti,Elena Percivalle,Julio C. C. Lorenzi,Federica Mazzola,Davide Magrì,Tereza Michalcikova,Jan Haviernik,Václav Hönig,Blanka Mrazkova,Natalie Polakova,Andrea Fortova,Jolana Tureckova,Veronika Iatsiuk,Salvatore Di Girolamo,Martin Palus,Dagmar Zudova,Petr Bednar,Ivana Bukova,Filippo Bianchini,Dora Mehn,Radim Nencka,Petra Straková,Oto Pavlis,Jan Rozman,Sabrina Gioria,Josè Camilla Sammartino,Federica Giardina,Stefano Gaiarsa,Qiang Pan Hammarström,Christopher O. Barnes,Pamela J. Bjorkman,Luigi Calzolai,Antonio Piralla,Fausto Baldanti,Michel C. Nussenzweig,Michel C. Nussenzweig,Paul D. Bieniasz,Paul D. Bieniasz,Theodora Hatziioannou,Jan Prochazka,Radislav Sedlacek,Davide F. Robbiani,Daniel Ruzek,Luca Varani +48 more
TL;DR: In this paper, a bispecific, IgG1-like molecule (CoV-X2) was developed based on two antibodies derived from COVID-19 convalescent donors, C121 and C1353.
Journal ArticleDOI
Advances in Modelling COVID-19 in Animals
TL;DR: All generated SARS-CoV2-related animal models to date are summarized, their suitability for COVID-19 research is evaluated, and the current and future state of the importance of animal models in this field are addressed.