P
Petrea Frid
Researcher at Lund University
Publications - 12
Citations - 546
Petrea Frid is an academic researcher from Lund University. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 6, co-authored 9 publications receiving 408 citations.
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Journal ArticleDOI
Congo red and protein aggregation in neurodegenerative diseases.
TL;DR: Understanding mechanisms involved in dye-amyloidal fibril binding and inhibition of aggregation will provide instructive guides for the design of future compounds, potentially useful for monitoring and treating neurodegenerative diseases.
Journal ArticleDOI
White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts – The MRI-GENIE study
Markus D. Schirmer,Markus D. Schirmer,Adrian V. Dalca,Ramesh Sridharan,Anne-Katrin Giese,Kathleen L. Donahue,Marco Nardin,Steven J. T. Mocking,Elissa C. McIntosh,Petrea Frid,Johan Wassélius,John W. Cole,Lukas Holmegaard,Christina Jern,Jordi Jimenez-Conde,Robin Lemmens,Arne Lindgren,James F. Meschia,Jaume Roquer,Tatjana Rundek,Ralph L. Sacco,Reinhold Schmidt,Pankaj Sharma,Agnieszka Slowik,Vincent Thijs,Daniel Woo,Achala Vagal,Huichun Xu,Steven J. Kittner,Patrick F. McArdle,Braxton D. Mitchell,Jonathan Rosand,Bradford B. Worrall,Ona Wu,Polina Golland,Natalia S. Rost +35 more
TL;DR: This work presents a fully automated pipeline for quantification of WMH in clinical large-scale studies of AIS, and obtains WMH volumes by building on an existing automatic WMH segmentation algorithm that delineates and distinguishes between different cerebrovascular pathologies.
Journal ArticleDOI
Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data
Ona Wu,Stefan Winzeck,Stefan Winzeck,Anne-Katrin Giese,Brandon L. Hancock,Mark R Etherton,Mark J. R. J. Bouts,Kathleen Donahue,Markus D. Schirmer,Robert E. Irie,Steven J. T. Mocking,Elissa C. McIntosh,Raquel Bezerra,Konstantinos Kamnitsas,Petrea Frid,Johan Wassélius,John W. Cole,Huichun Xu,Lukas Holmegaard,Jordi Jimenez-Conde,Robin Lemmens,Eric Lorentzen,Patrick F. McArdle,James F. Meschia,Jaume Roquer,Tatjana Rundek,Ralph L. Sacco,Reinhold Schmidt,Pankaj Sharma,Pankaj Sharma,Agnieszka Slowik,Tara M. Stanne,Vincent Thijs,Vincent Thijs,Achala Vagal,Daniel Woo,Stephen Bevan,Steven J. Kittner,Braxton D. Mitchell,Jonathan Rosand,Bradford B. Worrall,Christina Jern,Arne Lindgren,Jane Maguire,Natalia S. Rost +44 more
TL;DR: Both lesion volume and topography can provide insight into stroke subtypes with sufficient sample size from big heterogeneous multi-center clinical imaging phenotype data sets from the MRI-GENIE repository.
Journal ArticleDOI
Design and rationale for examining neuroimaging genetics in ischemic stroke: The MRI-GENIE study.
Anne-Katrin Giese,Markus D. Schirmer,Kathleen L. Donahue,Lisa Cloonan,Robert E. Irie,Stefan Winzeck,Mark J. R. J. Bouts,Elissa C. McIntosh,Steven J. T. Mocking,Adrian V. Dalca,Ramesh Sridharan,Huichun Xu,Petrea Frid,Eva Giralt-Steinhauer,Lukas Holmegaard,Jaume Roquer,Johan Wassélius,John W. Cole,Patrick F. McArdle,Joseph P. Broderick,Jordi Jimenez-Conde,Christina Jern,Brett M. Kissela,Dawn Kleindorfer,Robin Lemmens,Arne Lindgren,James F. Meschia,Tatjana Rundek,Ralph L. Sacco,Reinhold Schmidt,Pankaj Sharma,Pankaj Sharma,Agnieszka Slowik,Vincent Thijs,Vincent Thijs,Daniel Woo,Bradford B. Worrall,Steven J. Kittner,Braxton D. Mitchell,Jonathan Rosand,Polina Golland,Ona Wu,Natalia S. Rost +42 more
TL;DR: The MRI-GENIE study aims to develop, validate, and distribute the MRI analysis platform for scans acquired as part of clinical care for patients with AIS, which will lead to novel genetic discoveries in ischemic stroke, strategies for personalized stroke risk assessment, and personalized stroke outcome assessment.
Journal ArticleDOI
Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study.
Petrea Frid,Mattias Drake,Anne-Katrin Giese,Anne-Katrin Giese,Johan Wassélius,Markus D. Schirmer,Markus D. Schirmer,Kathleen L. Donahue,Lisa Cloonan,Robert E. Irie,Mark J. R. J. Bouts,Elissa C. McIntosh,Steven J. T. Mocking,Adrian V. Dalca,Adrian V. Dalca,Ramesh Sridharan,Huichun Xu,Eva Giralt-Steinhauer,Lukas Holmegaard,Lukas Holmegaard,Katarina Jood,Katarina Jood,Jaume Roquer,John W. Cole,Patrick F. McArdle,Joseph P. Broderick,Jordi Jimenez-Conde,Christina Jern,Brett M. Kissela,Dawn Kleindorfer,Robin Lemmens,Robin Lemmens,James F. Meschia,Tatjana Rundek,Ralph L. Sacco,Reinhold Schmidt,Pankaj Sharma,Pankaj Sharma,Agnieszka Slowik,Vincent Thijs,Daniel Woo,Bradford B. Worrall,Steven J. Kittner,Braxton D. Mitchell,Braxton D. Mitchell,Jesper Petersson,Jonathan Rosand,Polina Golland,Ona Wu,Natalia S. Rost,Arne Lindgren +50 more
TL;DR: Ischemic stroke subtypes differ between the two phenotypes and diabetes and male sex have a stronger association with PCiS than ACiS, which accounted for 47% of solitary brainstem infarctions.