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Philip L. F. Johnson
Researcher at University of Maryland, College Park
Publications - 47
Citations - 13262
Philip L. F. Johnson is an academic researcher from University of Maryland, College Park. The author has contributed to research in topics: Population & CRISPR. The author has an hindex of 25, co-authored 45 publications receiving 11581 citations. Previous affiliations of Philip L. F. Johnson include University of California, Berkeley & Emory University.
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Journal ArticleDOI
A Draft Sequence of the Neandertal Genome
Richard E. Green,Johannes Krause,Adrian W. Briggs,Tomislav Maricic,Udo Stenzel,Martin Kircher,Nick Patterson,Heng Li,Weiwei Zhai,Markus Hsi-Yang Fritz,Nancy F. Hansen,Eric Durand,Anna-Sapfo Malaspinas,Jeffrey D. Jensen,Tomas Marques-Bonet,Tomas Marques-Bonet,Can Alkan,Kay Prüfer,Matthias Meyer,Hernán A. Burbano,Jeffrey M. Good,Jeffrey M. Good,Rigo Schultz,Ayinuer Aximu-Petri,Anne Butthof,Barbara Höber,Barbara Höffner,Madien Siegemund,Antje Weihmann,Chad Nusbaum,Eric S. Lander,Carsten Russ,Nathaniel Novod,Jason P. Affourtit,Michael Egholm,Christine Verna,Pavao Rudan,Dejana Brajković,Željko Kućan,Ivan Gušić,Vladimir B. Doronichev,Liubov V. Golovanova,Carles Lalueza-Fox,Marco de la Rasilla,Javier Fortea,Antonio Rosas,Ralf Schmitz,Philip L. F. Johnson,Evan E. Eichler,Daniel Falush,Ewan Birney,James C. Mullikin,Montgomery Slatkin,Rasmus Nielsen,Janet Kelso,Michael Lachmann,David Reich,David Reich,Svante Pääbo +58 more
TL;DR: The genomic data suggest that Neandertals mixed with modern human ancestors some 120,000 years ago, leaving traces of Ne andertal DNA in contemporary humans, suggesting that gene flow from Neand Bertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.
Journal ArticleDOI
The complete genome sequence of a Neanderthal from the Altai Mountains
Kay Prüfer,Fernando Racimo,Nick Patterson,Flora Jay,Sriram Sankararaman,Susanna Sawyer,Anja Heinze,Gabriel Renaud,Peter H. Sudmant,Cesare de Filippo,Heng Li,Swapan Mallick,Michael Dannemann,Qiaomei Fu,Martin Kircher,Martin Kuhlwilm,Michael Lachmann,Matthias Meyer,Matthias Ongyerth,Michael Siebauer,Christoph Theunert,Arti Tandon,Priya Moorjani,Joseph K. Pickrell,James C. Mullikin,Samuel H. Vohr,Richard E. Green,Ines Hellmann,Philip L. F. Johnson,Hélène Blanché,Howard M. Cann,Jacob O. Kitzman,Jay Shendure,Evan E. Eichler,Ed S. Lein,Trygve E. Bakken,Liubov V. Golovanova,Vladimir B. Doronichev,Michael V. Shunkov,A.P. Derevianko,Bence Viola,Montgomery Slatkin,David Reich,Janet Kelso,Svante Pääbo +44 more
TL;DR: It is shown that interbreeding, albeit of low magnitude, occurred among many hominin groups in the Late Pleistocene and a definitive list of substitutions that became fixed in modern humans after their separation from the ancestors of Neanderthals and Denisovans is established.
Journal ArticleDOI
Genetic history of an archaic hominin group from Denisova Cave in Siberia
David Reich,Richard E. Green,Martin Kircher,Johannes Krause,Nick Patterson,Eric Durand,Bence Viola,Adrian W. Briggs,Udo Stenzel,Philip L. F. Johnson,Tomislav Maricic,Jeffrey M. Good,Tomas Marques-Bonet,Tomas Marques-Bonet,Can Alkan,Qiaomei Fu,Swapan Mallick,Swapan Mallick,Heng Li,Matthias Meyer,Evan E. Eichler,Mark Stoneking,Michael P. Richards,Sahra Talamo,Michael V. Shunkov,A.P. Derevianko,Jean-Jacques Hublin,Janet Kelso,Montgomery Slatkin,Svante Pääbo +29 more
TL;DR: A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.
Journal ArticleDOI
mapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters
TL;DR: This work describes mapDamage 2.0, a user-friendly package that extends the original features of mapDamage by incorporating a statistical model of DNA damage, and provides estimates of four key features of aDNA molecules: the average length of overhangs, nick frequency, cytosine deamination rates in both double-stranded regions and overhangers, and base quality scores according to their probability of being damaged.
Journal ArticleDOI
Genome sequence of a 45,000-year-old modern human from western Siberia
Qiaomei Fu,Heng Li,Priya Moorjani,Flora Jay,Sergey Mikhailovich Slepchenko,Aleksei A. Bondarev,Philip L. F. Johnson,Ayinuer Aximu-Petri,Kay Prüfer,Cesare de Filippo,Matthias Meyer,Nicolas Zwyns,Domingo C. Salazar-García,Yaroslav V. Kuzmin,Susan G. Keates,Pavel A. Kosintsev,Dmitry Razhev,Michael P. Richards,Nikolai V. Peristov,Michael Lachmann,Katerina Douka,Thomas Higham,Montgomery Slatkin,Jean-Jacques Hublin,David Reich,Janet Kelso,T. Bence Viola,Svante Pääbo +27 more
TL;DR: The high-quality genome sequence of a ∼45,000-year-old modern human male from Siberia derives from a population that lived before—or simultaneously with—the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians.