P
Philippe Colson
Researcher at Aix-Marseille University
Publications - 412
Citations - 21248
Philippe Colson is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Giant Virus & Medicine. The author has an hindex of 58, co-authored 361 publications receiving 17332 citations. Previous affiliations of Philippe Colson include Institut de recherche pour le développement & Centre national de la recherche scientifique.
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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.
Philippe Gautret,Jean-Christophe Lagier,Philippe Parola,Van Thuan Hoang,Line Meddeb,M. Mailhe,Barbara Doudier,Johan Courjon,Valérie Giordanengo,Vera Esteves Vieira,Hervé Tissot Dupont,Stéphane Honoré,Philippe Colson,Eric Chabrière,Bernard La Scola,Jean-Marc Rolain,Philippe Brouqui,Didier Raoult +17 more
TL;DR: Hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin, which was significantly more efficient for virus elimination.
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New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
TL;DR: The possible mechanisms of chloroquine interference with the SARS-CoV-2 replication cycle are discussed, which could lead to new therapies able to counter the most severe effects of the disease.
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Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards.
Bernard La Scola,Marion Le Bideau,Julien Andreani,Van Thuan Hoang,Clio Grimaldier,Philippe Colson,Philippe Gautret,Didier Raoult +7 more
TL;DR: Correlation between successful isolation of virus in cell culture and Ct value of quantitative RT-PCR targeting E gene suggests that patients with Ct above 33–34 using the RT- PCR system are not contagious and thus can be discharged from hospital care or strict confinement for non-hospitalized patients.
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Chloroquine and Hydroxychloroquine as Available Weapons to Fight COVID-19
Philippe Colson,Jean-Marc Rolain,Jean-Christophe Lagier,Philippe Brouqui,Didier Raoult,Didier Raoult +5 more
TL;DR: The Covid-19 pandemic triggered, more frequently, anxiety, depression, stress and post-traumatic stress disorders in the general population and health professionals Women, students and nurses are among the most affected.
Journal ArticleDOI
Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study.
Philippe Gautret,Jean-Christophe Lagier,Philippe Parola,Van Thuan Hoang,Line Meddeb,Jacques Sevestre,Morgane Mailhe,Barbara Doudier,Camille Aubry,Sophie Amrane,Piseth Seng,Marie Hocquart,Carole Eldin,Julie Finance,Vera Esteves Vieira,Hervé Tissot-Dupont,Stéphane Honoré,Andreas Stein,Matthieu Million,Philippe Colson,Bernard La Scola,Véronique Veit,Alexis Jacquier,Jean Claude Deharo,Michel Drancourt,Pierre-Edouard Fournier,Jean-Marc Rolain,Philippe Brouqui,Didier Raoult +28 more
TL;DR: There is urgency to evaluate the effectiveness of this potentially-life saving therapeutic strategy at a larger scale, both to treat and cure patients at an early stage before irreversible severe respiratory complications take hold and to decrease duration of carriage and avoid the spread of the disease.