P
Phoebe A. Rice
Researcher at University of Chicago
Publications - 95
Citations - 10360
Phoebe A. Rice is an academic researcher from University of Chicago. The author has contributed to research in topics: DNA & Recombinase. The author has an hindex of 39, co-authored 89 publications receiving 9872 citations. Previous affiliations of Phoebe A. Rice include Laboratory of Molecular Biology & Duke University.
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Journal ArticleDOI
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor.
TL;DR: A 3.5 angstrom resolution electron density map of the HIV-1 reverse transcriptase heterodimer complexed with nevirapine, a drug with potential for treatment of AIDS, reveals an asymmetric dimer.
BookDOI
Mobile DNA III
Nancy L. Craig,Michael Chandler,Martin Gellert,Alan M. Lambowitz,Phoebe A. Rice,Suzanne Sandmeyer +5 more
TL;DR: This new edition of the bestselling series on movable genetic elements highlights the many exciting advances in the field over the last decade, including conservative site-specific recombination, programmed rearrangements, DNA-only transposons, and LTR, and non-LTR retrotransposons.
Journal ArticleDOI
Crystal structure of an ihf-dna complex : a protein-induced dna u-turn
TL;DR: The crystal structure of IHF complexed with 35 bp of DNA is reported, providing evidence for the importance of a narrow minor groove in IHF's binding sequence.
Journal ArticleDOI
Mechanisms of Site-Specific Recombination*
TL;DR: Details of the site-specific recombination processes have been revealed by recent structural and biochemical studies of members of both families, named after the amino acid residue that forms a covalent protein-DNA linkage in the reaction intermediate.
Journal ArticleDOI
IHF and HU: flexible architects of bent DNA.
Kerren K. Swinger,Phoebe A. Rice +1 more
TL;DR: In prokaryotes, IHF and HU are key architectural proteins present at high concentrations, and the adaptation of advanced biophysical and biochemical techniques have led to an improved understanding of how these proteins interact with DNA.