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Pietro Ferraro

Bio: Pietro Ferraro is an academic researcher from National Research Council. The author has contributed to research in topics: Digital holography & Holography. The author has an hindex of 61, co-authored 653 publications receiving 12666 citations. Previous affiliations of Pietro Ferraro include Aeritalia & Centre national de la recherche scientifique.


Papers
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Proceedings ArticleDOI
13 Apr 2020
Abstract: The effective detection of low-concentrated molecules in small volumes represents a significant challenge in many sectors such as biomedicine, safety, and pollution. Here, we show an easy way to dispense liquid droplets from few μl volume (0.2-0.5 μl) of a mother drop, used as reservoir, by using a pyro-electrohydro-dynamic jetting (p-jet) dispenser. This system is proposed for multi-purpose applications such as printing viscous fluids and as a biosensor system. The p-jet system is based on the pyroelectric effect of polar dielectric crystals such as lithium niobate (LN). The electric field generated by the pyroelectric effect acts electro-hydrodynamically on the sample of liquid, allowing the deposition of small volumes. The p-jet approach allows to obtain the dispensing of drops of very small volumes (up to tenths of a picoliter) avoiding the use of syringes and nozzles generally used in standard technologies. The reliability of the technique as a biosensor is demonstrated both in the case of oligonucleotides and in a sample of clinical interest, namely gliadin. The results show the possibility of detecting these biomolecules even when they are low abundant, i.e. down to attomolar. The results show a marked improvement in the detection limit (LOD) when compared with the conventional technique (ELISA). Moreover, it has been presented the possibility of using the p-jet as a useful tool in the detection of biomarkers, present in the blood but currently not detectable with conventional techniques and related to neurodegenerative diseases such as Alzheimer.

1 citations

Proceedings ArticleDOI
TL;DR: In this paper, an automatic procedure, inserted in the hologram reconstruction process, was developed to selectively filter the holographic spectrum, thus increasing the accuracy of the conveyed information and measures performed on images.
Abstract: Digital holography (DH) is a well-established interferometric tool in optical metrology allowing the investigation of engineered surface shapes with microscale lateral resolution and nanoscale axial precision. With the advent of charged coupled devices (CCDs) with smaller pixel sizes, high speed computers and greater pixel numbers, DH became a very feasible technology which offers new possibilities for a large variety of applications. DH presents numerous advantages such as the direct access to the phase information, numerical correction of optical aberrations and the ability of a numerical refocusing from a single hologram. Furthermore, as an interferometric method, DH offers both a nodestructive and no-contact approach to very fragile objects combined with flexibility and a high sensitivity to geometric quantities such as thicknesses and displacements. These features recommend it for the solution of many imaging and measurements problems, such as microelectro-optomechanical systems (MEMS/MEOMS) inspection and characterization. In this work, we propose to improve the performance of a DH measurement on MEMS devices, through digital filters. We have developed an automatic procedure, inserted in the hologram reconstruction process, to selectively filter the hologram spectrum. The purpose is to provide very few noisy reconstructed images, thus increasing the accuracy of the conveyed information and measures performed on images. Furthermore, improving the image quality, we aim to make this technique application as simple and as accurate as possible.

1 citations

Proceedings ArticleDOI
TL;DR: In this paper, the authors demonstrate that ultrasound field calibration and imaging are achievable in a vertical resonator using digital holography, showing that it is a flexible tool to assist the diffusion of acoustophoresis microfluidic devices.
Abstract: We demonstrate that ultrasound field calibration and imaging are achievable in a vertical resonator using digital holography, showing that it is a flexible tool to assist the diffusion of acoustophoresis microfluidic devices.

1 citations

Book ChapterDOI
01 Jan 2018
TL;DR: The novel concept proposed, based on the activation of the pyroelectrodynamic effect, offers the ability of working on fluidic multiphase materials for processing biomaterials (biocompatible and biodegradable) in order to fabricate scaffold for tissue engineering application and high-viscous polymers for the fabrication of 3D microobjects, avoiding the typical chaotic spiraling effect usually occurring in conventional electrospinning systems.
Abstract: The possibility of shaping the soft matter into complex patterned structures is becoming very important in the realm of nanotechnology. Microelectronic components, flexible electronic circuits, optical waveguides, microlenses, 3D scaffolds for tissue engineering, biomaterials, and biosensors are just a few examples of possible applications of high-resolution patterns. Many different approaches have been developed and tested for materials manipulation and microfabrication purposes. Very recently, the ink-jet printing approach has opened new frontiers for noncontact printing and high-resolution dispensing. The advantages of the ink-jet printing approach also have been expanded by the invention of 3D printers actually used to synthesize a three-dimensional object through the new concept of additive manufacturing process. The work and the experiments reported in this chapter are related to the description of an unconventional approach developed for the manipulation of liquid and polymeric materials. The novel concept proposed, based on the activation of the pyroelectrodynamic effect, offers the ability of working on fluidic multiphase materials for processing biomaterials (biocompatible and biodegradable) in order to fabricate scaffold for tissue engineering application and high-viscous polymers for the fabrication of 3D microobjects, avoiding the typical chaotic spiraling effect usually occurring in conventional electrospinning systems.

1 citations


Cited by
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Journal Article
TL;DR: In this article, a fast Fourier transform method of topography and interferometry is proposed to discriminate between elevation and depression of the object or wave-front form, which has not been possible by the fringe-contour generation techniques.
Abstract: A fast-Fourier-transform method of topography and interferometry is proposed. By computer processing of a noncontour type of fringe pattern, automatic discrimination is achieved between elevation and depression of the object or wave-front form, which has not been possible by the fringe-contour-generation techniques. The method has advantages over moire topography and conventional fringe-contour interferometry in both accuracy and sensitivity. Unlike fringe-scanning techniques, the method is easy to apply because it uses no moving components.

3,742 citations

Journal ArticleDOI
TL;DR: In this paper, the authors review the recent developments in the area of optical fiber grating sensors, including quasi-distributed strain sensing using Bragg gratings, systems based on chirped gratings and intragrating sensing concepts.
Abstract: We review the recent developments in the area of optical fiber grating sensors, including quasi-distributed strain sensing using Bragg gratings, systems based on chirped gratings, intragrating sensing concepts, long period-based grating sensors, fiber grating laser-based systems, and interferometric sensor systems based on grating reflectors.

3,665 citations

01 Jan 2006

3,012 citations