P
Pius Loetscher
Researcher at Novartis
Publications - 83
Citations - 15521
Pius Loetscher is an academic researcher from Novartis. The author has contributed to research in topics: Chemokine & Chemokine receptor. The author has an hindex of 50, co-authored 79 publications receiving 14960 citations. Previous affiliations of Pius Loetscher include University Hospital of Bern & University of Zurich.
Papers
More filters
Journal ArticleDOI
Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
Federica Sallusto,Patrick Schaerli,Pius Loetscher,Christoph Schaniel,Danielle Lenig,Charles R. Mackay,Shixin Qin,Antonio Lanzavecchia +7 more
TL;DR: Different patterns of chemokine receptors in immature and mature DC are consistent with “inflammatory” and “primary response” phases of DC function.
Journal ArticleDOI
Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes.
Marcel Loetscher,B Gerber,Pius Loetscher,Simon Arnett Jones,Luca Piali,Ian Clark-Lewis,Marco Baggiolini,Bernhard Moser +7 more
TL;DR: The present observations suggest that the IP10/Mig receptor is involved in the selective recruitment of effector T cells.
Journal ArticleDOI
Lymphocyte traffic control by chemokines.
Bernhard Moser,Pius Loetscher +1 more
TL;DR: Recent developments in this area justify the hypothesis that the distinct migration patterns of lymphocytes throughout their life cycle are finely tuned by changing sets of chemokines that are selective for developmentally regulated chemokine receptors.
Journal ArticleDOI
Cxc Chemokine Receptor 5 Expression Defines Follicular Homing T Cells with B Cell Helper Function
Patrick Schaerli,Katharina Willimann,Alois B. Lang,Martin Lipp,Pius Loetscher,Bernhard Moser +5 more
TL;DR: These properties portray CXCR5+ T cells as a distinct memory T cell subset with B cell helper function, designated here as follicular B helper T cells (TFH).
Journal ArticleDOI
CCR5 is characteristic of Th1 lymphocytes
Pius Loetscher,Mariagrazia Uguccioni,Lorenza Bordoli,Marco Baggiolini,Bernhard Moser,Carlo Chizzolini,Jean-Michel Dayer +6 more
TL;DR: Two additional chemokine receptors, CCR5 and CXCR3, are studied in human, antigen-specific CD4+ Th1 and Th2 cell clones, which function in allergy and humoral immunity to parasites.