P
Pompilia Ispas-Szabo
Researcher at Université du Québec à Montréal
Publications - 32
Citations - 1125
Pompilia Ispas-Szabo is an academic researcher from Université du Québec à Montréal. The author has contributed to research in topics: Starch & Controlled release. The author has an hindex of 14, co-authored 29 publications receiving 988 citations.
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Journal ArticleDOI
N-acylated chitosan: hydrophobic matrices for controlled drug release.
TL;DR: Drug dissolution kinetics showed longer release times for higher degrees of functionalization, suggesting palmitoyl chitosan excipients as interesting candidates for oral and subdermal pharmaceutical applications.
Journal ArticleDOI
Development of biodegradable films from whey proteins by cross-linking and entrapment in cellulose.
C. Le Tien,M Letendre,Pompilia Ispas-Szabo,Mircea-Alexandru Mateescu,G. Delmas-Patterson,H L Yu,Monique Lacroix +6 more
TL;DR: X-ray diffraction analysis suggests that cross-linking by gamma-irradiation seems to modify the conformation of proteins, which became more ordered and more stable.
Journal ArticleDOI
Cross-linked high amylose starch derivatives as matrices for controlled release of high drug loadings.
TL;DR: These new polymeric excipients are able to control the release over 20 h from monolithic tablets loaded with 20 to 60% drug and represent a novel generation of pharmaceuticalexcipients recommended for high loading dosage formulations.
Journal ArticleDOI
Structure-properties relationship in cross-linked high-amylose starch for use in controlled drug release
TL;DR: Best release properties and highest mechanical hardness were obtained from CLHAS matrices with low-to-moderate crystallinity, where the V- and the B-type structures coexist with amorphous regions.
Journal ArticleDOI
Structure-properties relationship in cross-linked high amylose starch cast films
Bernard Rioux,Pompilia Ispas-Szabo,Abdellatif Ait-Kadi,Mircea-Alexandru Mateescu,Julianna Juhasz +4 more
TL;DR: In this paper, the effect of cross-linked high amylose starch cast films on various properties in normal environmental conditions were determined as a function of crosslinker degree and percentage of free humidity.