The power of feedback.

Cause, conseguenze e strategie di mitigazione Proponiamo il primo di una serie di articoli in cui affronteremo l’attuale problema dei mutamenti climatici. Presentiamo il documento redatto, votato e pubblicato dall’Ipcc - Comitato intergovernativo sui cambiamenti climatici - che illustra la sintesi delle ricerche svolte su questo tema rilevante.

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Climate Change 2007: The Physical Science Basis.

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular riskThe Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)

Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. This process can be modified by lifestyle adjustments, pharmacological therapies, and invasive interventions designed to achieve disease stabilization or regression. The disease can have long, stable periods but can also become unstable at any time, typically due to an acute atherothrombotic event caused by plaque rupture or erosion. However, the disease is chronic, most often progressive, and hence serious, even in clinically apparently silent periods. The dynamic nature of the CAD process results in various clinical presentations, which can be conveniently categorized as either acute coronary syndromes (ACS) or chronic coronary syndromes (CCS). The Guidelines presented here refer to the management of patients with CCS. The natural history of CCS is illustrated in Figure 1.

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2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes.

The talk with present the key results of the IPCC Working Group III 5th assessment report. Concluding four years of intense scientific collaboration by hundreds of authors from around the world, the report responds to the request of the world's governments for a comprehensive, objective and policy neutral assessment of the current scientific knowledge on mitigating climate change. The report has been extensively reviewed by experts and governments to ensure quality and comprehensiveness.

Climate change 2014 - Mitigation of climate change

Non-linear periodic long waves based on Boussinesq equation for shallow water waves: A coupled FEM modeling

Pro-Environmental Potential in Activity-Travel Routine of Individuals: A Data Driven Computational Algorithm

Rapid progress in next generation sequencing technologies provided deeper insights into the mechanism underlying disease pathology. It has broadened our horizon to understand the cellular processes at individual cell level. Single-cell analysis allowed uncovering new dimensions that could track the trajectories of distant cell lineage in tumor development. In recent years, the popularity of single-cell omics gained utmost momentum. Our review focuses on the use of single-cell omics in cellular model of cancer and its clinical application. It also highlights the potential of using multiomics approach to understand the cellular heterogeneity at multiple layers. The data generated using single-cell multiomics revealed the key biological processes, mechanism of cellular heterogeneity, and resistance mechanism. The knowledge captured from the single-cell analysis facilitated a wider understanding of disease and in developing efficient treatment strategies.

Single-Cell Multiomics: Dissecting Cancer

Exposure and dose assessment of school children to air pollutants in a tropical coastal-urban area.

Response to discussion on: “An integrated statistical approach for evaluating the exceedance of criteria pollutants in the ambient air of megacity Delhi”, Atmospheric Environment

Prashant Kumar

Papers

Non-linear periodic long waves based on Boussinesq equation for shallow water waves: A coupled FEM modeling

Pro-Environmental Potential in Activity-Travel Routine of Individuals: A Data Driven Computational Algorithm

Single-Cell Multiomics: Dissecting Cancer

Exposure and dose assessment of school children to air pollutants in a tropical coastal-urban area.

Response to discussion on: “An integrated statistical approach for evaluating the exceedance of criteria pollutants in the ambient air of megacity Delhi”, Atmospheric Environment