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Prem Chandra Pandey

Bio: Prem Chandra Pandey is a academic researcher from Shiv Nadar University. The author has contributed to research in topic(s): Cyclic voltammetry & Ormosil. The author has an hindex of 24, co-authored 81 publication(s) receiving 1462 citation(s). Previous affiliations of Prem Chandra Pandey include Birla Institute of Technology, Mesra & Tel Aviv University. more

Topics: Cyclic voltammetry, Ormosil, Glucose oxidase more
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Journal ArticleDOI
Abstract: A non-mediated glucose biosensor is reported based on encapsulated glucose oxidase (GOD) within the composite sol–gel glass, which is prepared using optimum concentrations of 3-aminopropyltriethoxy silane, 2-(3, 4-epoxycyclohexyl)-ethyltrimethoxy silane, GOD dissolved in double distilled water and HCl. A white, smooth film of sol–gel glass with controlled thickness is also prepared at the surface of a Pt disk electrode without GOD to study the electrochemistry of ferrocene monocarboxylic acid at the surface of the modified electrode. The electrochemistry of ferrocene monocarboxylic acid at composite sol–gel glass electrode with varying thickness is reported. The GOD-immobilized film over the Pt disk surface shows a yellow colour. The new sol–gel glass in the absence and the presence of GOD is characterized by scanning electron microscopy (SEM). The enzyme-immobilized film of different thickness is made using varying concentrations of soluble sol–gel components applied to the well of the Pt disk electrode. The enzyme is cross-lined with the 3-aminopropyltriethoxysilane, one of the composite component of sol–gel glass using glyoxal at 4°C for 4 h. The response of non-mediated enzyme sensor is studied based on cyclic voltammetry and amperometric measurements. A typical amperometric response of the enzyme sensor having varying thickness of the modified sol–gel glass film is reported. The variation of the response time as a function of the film thickness is reported. The stability of cross-linked GOD to sol–gel glass is found to be more than a month without loss of enzymatic activity when the enzyme sensor is stored at 4°C. more

78 citations

Journal ArticleDOI
01 Jan 1999-Electroanalysis
Abstract: A new glucose biosensor was developed based on the sandwich configuration of organically modified sol-gel glasses. The new sol-gel glass was developed using 3-aminopropyltrimethoxy silane and 2-(3,4-epoxycyclohexyl)-ethyltrimethoxy silane. Two types of sol-gel glasses were used to develop glucose biosensors that differ in absence (A) and the presence of graphite powder [particle size 1–2 μ] (B). An additional additive (polyethylene glycol, Mol. wt. 6000) was also incorporated in both types of the upper sol-gel glass layer. The new sol-gel matrix with immobilized glucose oxidase was analyzed by scanning electron microscopy (SEM).The sandwich configuration was developed using a bilayer of sol-gel glasses having a layer of glucose oxidase in between the bilayer. This electrode with special configuration was used to form a layer of sol-gel glass of ca. 0.2 mm thickness. The performance of sol-gel glasses (A & B) was analyzed based on cyclic voltammetry using ferrocene monocarboxylic acid. The results show a diffusion limited condition of ferrocene across the sol-gel matrix. The characterization of sol-gel glass based biosensor was recorded based on the cyclic voltammograms in absence and presence of glucose. The results show an increase in anodic current which is also characteristic of hydrogen peroxide oxidation in both cases (A & B). The responses of the sol-gel glasses based biosensors were analyzed based on chronoamperometric measurements. An amplified signal on the addition of the same concentrations of glucose was recorded with the B-type sol-gel glass electrode which was attributed to its relatively high porosity and better conductivity of the graphite loaded sol-gel glass. These observations were in accordance with the results on the diffusion of ferrocene and the magnitude of anodic current resulting from hydrogen peroxide oxidation. The calibration plots for glucose analysis using both type of sensors are reported. Data on the mediated electrochemical oxidation of glucose oxidase using soluble ferrocene were also reported based on cyclic voltammograms and amperometric measurement. more

69 citations

Journal ArticleDOI
Abstract: Land consumption is increasing rapidly with the exponential growth of population. The built-up environment configuration influences the management processes for development and other municipality works. Population growth also affects the availability of land for different purposes in its spatial distribution. The present study was conducted using satellite remote sensing data Landsat MSS (Multi-spectral Scanner), ETM+ (Enhanced Thematic Mapper), IRS P-6 (Indian Remote Sensing Satellite), LISS IV (Linear Imaging Self-Scanner), and IRS P-5 Cartosat-1 for the assessment of urban area change dynamics between years 1976 and 2008 in Bhagalpur city in the state of Bihar in India. The ground truth and coordinate points were collected using a Global Positioning System (GPS) for the location of the built-up themes prepared in the Geographic Information System (GIS). Land Consumption Rate (LCR) and Land Absorption Coefficient (LAC) were introduced to aid in the quantitative assessment changes. The results show a rap... more

69 citations

Journal ArticleDOI
TL;DR: This paper presents the implementation of a Geospatial approach for improving the Municipal Solid Waste disposal suitability site assessment in growing urban environment using Multi Criteria Geographical Information System and Remote Sensing for selection of suitable disposal sites. more

Abstract: This paper presents the implementation of a Geospatial approach for improving the Municipal Solid Waste (MSW) disposal suitability site assessment in growing urban environment. The increasing trend of population growth and the absolute amounts of waste disposed of worldwide have increased substantially reflecting changes in consumption patterns, consequently worldwide. MSW is now a bigger problem than ever. Despite an increase in alternative techniques for disposing of waste, land-filling remains the primary means. In this context, the pressures and requirements placed on decision makers dealing with land-filling by government and society have increased, as they now have to make decisions taking into considerations environmental safety and economic practicality. The waste disposed by the municipal corporation in the Bhagalpur City (India) is thought to be different from the landfill waste where clearly scientific criterion for locating suitable disposal sites does not seem to exist. The location of disposal sites of Bhagalpur City represents the unconsciousness about the environmental and public health hazards arising from disposing of waste in improper location. Concerning about urban environment and health aspects of people, a good method of waste management and appropriate technologies needed for urban area of Bhagalpur city to improve this trend using Multi Criteria Geographical Information System and Remote Sensing for selection of suitable disposal sites. The purpose of GIS was to perform process to part restricted to highly suitable land followed by using chosen criteria. GIS modeling with overlay operation has been used to find the suitability site for MSW. more

50 citations

Journal ArticleDOI
Prem Chandra Pandey1, S. Upadhyay1, Ida Tiwari1, Gyanendra Singh1  +1 moreInstitutions (1)
Abstract: A novel finding on the development of electrocatalytic biosensor for dopamine is reported. The new electrocatalytic dopamine biosensor is developed using ferrocene encapsulated palladium (Pd)-linked organically-modified sol–gel glass (ormosil). The alkoxy precursors used for the preparation of new ormosil-based electrocatalytic biosensor are palladium-linked glycidoxypropyltrimethoxysilane and trimethoxysilane. The optimum concentrations of these precursors are added in aqueous solution of ferrocene monocarboxylic acid and HCl followed by gelation for 30 h at 25°C to form ormosil. The ferrocene encapsulated ormosil is characterized based on cyclic voltammetric measurements. The CV results shows peak separation of 57–59 mV and a linear relation between peak current and square root of scan rate suggesting well behaved reversible electrochemistry of ormosil encapsulated ferrocene. The CV results and the detection of ferrocene in working medium shows that ferrocene is not leached out of ormosil matrix. The tyrosinase is immobilized within polyvinyl alcohol over the ferrocene encapsulated new ormosil and finally mounted using nucleopore membrane. The electrocatalytic response of immobilized tyrosinase over new ormosil is observed and the results are reported. The performance, stability, and reproducibility of new ormosil-based dopamine biosensor are reported. more

47 citations

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Journal ArticleDOI
Krishnendu Saha1, Sarit S. Agasti1, Chaekyu Kim1, Xiaoning Li1  +1 moreInstitutions (1)
02 Feb 2012-Chemical Reviews
TL;DR: The advent of AuNP as a sensory element provided a broad spectrum of innovative approaches for the detection of metal ions, small molecules, proteins, nucleic acids, malignant cells, etc. in a rapid and efficient manner. more

Abstract: Detection of chemical and biological agents plays a fundamental role in biomedical, forensic and environmental sciences1–4 as well as in anti bioterrorism applications.5–7 The development of highly sensitive, cost effective, miniature sensors is therefore in high demand which requires advanced technology coupled with fundamental knowledge in chemistry, biology and material sciences.8–13 In general, sensors feature two functional components: a recognition element to provide selective/specific binding with the target analytes and a transducer component for signaling the binding event. An efficient sensor relies heavily on these two essential components for the recognition process in terms of response time, signal to noise (S/N) ratio, selectivity and limits of detection (LOD).14,15 Therefore, designing sensors with higher efficacy depends on the development of novel materials to improve both the recognition and transduction processes. Nanomaterials feature unique physicochemical properties that can be of great utility in creating new recognition and transduction processes for chemical and biological sensors15–27 as well as improving the S/N ratio by miniaturization of the sensor elements.28 Gold nanoparticles (AuNPs) possess distinct physical and chemical attributes that make them excellent scaffolds for the fabrication of novel chemical and biological sensors (Figure 1).29–36 First, AuNPs can be synthesized in a straightforward manner and can be made highly stable. Second, they possess unique optoelectronic properties. Third, they provide high surface-to-volume ratio with excellent biocompatibility using appropriate ligands.30 Fourth, these properties of AuNPs can be readily tuned varying their size, shape and the surrounding chemical environment. For example, the binding event between recognition element and the analyte can alter physicochemical properties of transducer AuNPs, such as plasmon resonance absorption, conductivity, redox behavior, etc. that in turn can generate a detectable response signal. Finally, AuNPs offer a suitable platform for multi-functionalization with a wide range of organic or biological ligands for the selective binding and detection of small molecules and biological targets.30–32,36 Each of these attributes of AuNPs has allowed researchers to develop novel sensing strategies with improved sensitivity, stability and selectivity. In the last decade of research, the advent of AuNP as a sensory element provided us a broad spectrum of innovative approaches for the detection of metal ions, small molecules, proteins, nucleic acids, malignant cells, etc. in a rapid and efficient manner.37 Figure 1 Physical properties of AuNPs and schematic illustration of an AuNP-based detection system. In this current review, we have highlighted the several synthetic routes and properties of AuNPs that make them excellent probes for different sensing strategies. Furthermore, we will discuss various sensing strategies and major advances in the last two decades of research utilizing AuNPs in the detection of variety of target analytes including metal ions, organic molecules, proteins, nucleic acids, and microorganisms. more

3,442 citations

01 Jan 2016-
TL;DR: The remote sensing and image interpretation is universally compatible with any devices to read and is available in the digital library an online access to it is set as public so you can get it instantly. more

Abstract: Thank you very much for downloading remote sensing and image interpretation. As you may know, people have look hundreds times for their favorite novels like this remote sensing and image interpretation, but end up in malicious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they are facing with some malicious virus inside their computer. remote sensing and image interpretation is available in our digital library an online access to it is set as public so you can get it instantly. Our book servers spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the remote sensing and image interpretation is universally compatible with any devices to read. more

1,550 citations

02 Jan 1991-

1,339 citations

Journal ArticleDOI
Abstract: Because their chemical and physical properties may be tailored over a wide range of characteristics, the use of polymers is finding a permanent place in sophisticated electronic measuring devices such as sensors. During the last 5 years, polymers have gained tremendous recognition in the field of artificial sensor in the goal of mimicking natural sense organs. Better selectivity and rapid measurements have been achieved by replacing classical sensor materials with polymers involving nano technology and exploiting either the intrinsic or extrinsic functions of polymers. Semiconductors, semiconducting metal oxides, solid electrolytes, ionic membranes, and organic semiconductors have been the classical materials for sensor devices. The developing role of polymers as gas sensors, pH sensors, ion-selective sensors, humidity sensors, biosensor devices, etc., are reviewed and discussed in this paper. Both intrinsically conducting polymers and non-conducting polymers are used in sensor devices. Polymers used in sensor devices either participate in sensing mechanisms or immobilize the component responsible for sensing the analyte. Finally, current trends in sensor research and also challenges in future sensor research are discussed. more

1,051 citations

Journal ArticleDOI
TL;DR: The review covers main applications of conducting polymers in chemical sensors and biosensors, such as pH sensitivity, sensitivity to inorganic ions and organic molecules as well as sensitivity to gases, and induced receptor properties. more

Abstract: The review covers main applications of conducting polymers in chemical sensors and biosensors The first part is focused on intrinsic and induced receptor properties of conducting polymers, such as pH sensitivity, sensitivity to inorganic ions and organic molecules as well as sensitivity to gases Induced receptor properties can be also formed by molecularly imprinted polymerization or by immobilization of biological receptors Immobilization strategies are reviewed in the second part The third part is focused on applications of conducting polymers as transducers and includes usual optical (fluorescence, SPR, etc) and electrical (conductometric, amperometric, potentiometric, etc) transducing techniques as well as organic chemosensitive semiconductor devices An assembly of stable sensing structures requires strong binding of conducting polymers to solid supports These aspects are discussed in the next part Finally, an application of combinatorial synthesis and high-throughput analysis to the development and optimization of sensing materials is described more

754 citations

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Author's H-index: 24

No. of papers from the Author in previous years

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Author's top 5 most impactful journals


9 papers, 281 citations

Sensors and Actuators B-chemical

6 papers, 230 citations

Biosensors and Bioelectronics

3 papers, 66 citations

IEEE Sensors Journal

3 papers, 50 citations