P
Priyanka Singh
Researcher at Indian Institute of Technology, Jodhpur
Publications - 25
Citations - 674
Priyanka Singh is an academic researcher from Indian Institute of Technology, Jodhpur. The author has contributed to research in topics: Centrosome & Microtubule. The author has an hindex of 12, co-authored 22 publications receiving 501 citations. Previous affiliations of Priyanka Singh include University of Münster & University of Basel.
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Journal ArticleDOI
Molecular basis of outer kinetochore assembly on CENP-T.
Pim J Huis in 't Veld,Sadasivam Jeganathan,Arsen Petrovic,Priyanka Singh,Juliane John,Veronica Krenn,Florian Weissmann,Tanja Bange,Andrea Musacchio,Andrea Musacchio +9 more
TL;DR: Reconstituted the binding of the MIS12 and NDC80 outer kinetochore subcomplexes to CENP-C and C ENP-T provides a molecular explanation for the stoichiometry of kinetchore components and its cell cycle regulation.
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Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA.
TL;DR: This work demonstrates for the first time that Pdcd4 is directly involved in translational suppression of a natural mRNA with a 5′-structured UTR and provides novel insight into the translational control of p53 expression.
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BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis.
Priyanka Singh,Marion E. Pesenti,Stefano Maffini,Sara Carmignani,Marius Hedtfeld,Arsen Petrovic,Anupallavi Srinivasamani,Tanja Bange,Andrea Musacchio,Andrea Musacchio +9 more
TL;DR: It is demonstrated that most and likely all of the PLK1 is recruited through BUB1 in the outer kinetochore and centromeric protein U (CENP-U) in the inner kinetchore, a unifying mechanism for recruitment ofPLK1 to human Kinetochores.
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Rootletin organizes the ciliary rootlet to achieve neuron sensory function in Drosophila
Jieyan V. Chen,Ling-Rong Kao,Swadhin Chandra Jana,Elena Sivan-Loukianova,Susana Mendonça,Oscar A. Cabrera,Priyanka Singh,Clemens Cabernard,Daniel F. Eberl,Mónica Bettencourt-Dias,Timothy L. Megraw +10 more
TL;DR: Drosophila Rootletin organizes rootlets in sensory neurons, where it transmits multiple sensory inputs and maintains basal body cohesion, yet it is not required for cilium stability.
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The Microcephaly-Associated Protein Wdr62/CG7337 Is Required to Maintain Centrosome Asymmetry in Drosophila Neuroblasts.
Anjana Ramdas Nair,Priyanka Singh,David Salvador Garcia,David Rodriguez-Crespo,Boris Egger,Clemens Cabernard +5 more
TL;DR: It is proposed that CG7337/Wdr62, a microtubule-associated protein, is required for the maintenance of interphase microtubules, thereby regulating centrosomal Polo and Plp levels.