P
Pui Lai Rachel Ee
Researcher at National University of Singapore
Publications - 63
Citations - 4342
Pui Lai Rachel Ee is an academic researcher from National University of Singapore. The author has contributed to research in topics: Self-healing hydrogels & Antimicrobial peptides. The author has an hindex of 29, co-authored 55 publications receiving 3584 citations. Previous affiliations of Pui Lai Rachel Ee include University of Illinois at Chicago.
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Journal ArticleDOI
Graphene for Controlled and Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells
Tapas R. Nayak,Henrik Andersen,Venkata S. Makam,Clement Khaw,Sukang Bae,Xiangfan Xu,Pui Lai Rachel Ee,Jong Hyun Ahn,Byung Hee Hong,Giorgia Pastorin,Giorgia Pastorin,Barbaros Özyilmaz,Barbaros Özyilmaz +12 more
TL;DR: It is shown that graphene provides a promising biocompatible scaffold that does not hamper the proliferation of human mesenchymal stem cells and accelerates their specific differentiation into bone cells, demonstrating graphene's potential for stem cell research.
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The effects of polymeric nanostructure shape on drug delivery.
Shrinivas Venkataraman,James L. Hedrick,Zhan Yuin Ong,Chuan Yang,Pui Lai Rachel Ee,Paula T. Hammond,Yi Yan Yang +6 more
TL;DR: Different approaches to fabricate polymeric nanostructures of various shapes are reviewed, a comprehensive summary on the current understandings of the influence of nanostructure with different shapes on important biological processes in drug delivery is provided, and future perspectives for the development of nanstructures with well-defined shapes for drug delivery are discussed.
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Mixed micelles self-assembled from block copolymers for drug delivery
Amalina Bte Ebrahim Attia,Zhan Yuin Ong,James L. Hedrick,Phin Peng Lee,Pui Lai Rachel Ee,Paula T. Hammond,Yi Yan Yang +6 more
TL;DR: This review is focused on the various strategies used to form and stabilize mixed micelles for drug delivery and the methodologies employed to ascertain the establishment of mixed micelle formation.
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Identification of a Novel Estrogen Response Element in the Breast Cancer Resistance Protein (ABCG2) Gene
Pui Lai Rachel Ee,Sitharthan Kamalakaran,Debra A. Tonetti,Xiaolong He,Douglas D. Ross,William T. Beck +5 more
TL;DR: It is shown that estrogen enhanced the expression of BCRP mRNA in the estrogen receptor (ER)-positive T47D:A18 cells and PA-1 cells stably expressing ERα, and evidence is provided herein for a novel ERE in the B CRP promoter.
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Biomimetic hydrogels for chondrogenic differentiation of human mesenchymal stem cells to neocartilage
TL;DR: This soft PEG/CMP hydrogel shows promise as a biomimetic scaffold that provides a desirable environment for the chondrogenic differentiation of hMSCs and is useful for the repair of cartilage defects.