Author
Purnendu K. Dasgupta
Other affiliations: Dow Chemical Company, Texas Tech University, University of California, Davis ...read more
Bio: Purnendu K. Dasgupta is an academic researcher from University of Texas at Arlington. The author has contributed to research in topics: Ion chromatography & Detection limit. The author has an hindex of 62, co-authored 506 publications receiving 16779 citations. Previous affiliations of Purnendu K. Dasgupta include Dow Chemical Company & Texas Tech University.
Papers published on a yearly basis
Papers
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TL;DR: A microfabricated moisture sensor with interdigitated Au or Pt electrodes on a silicon substrate with response reproducibility of an individual sensor is <1%, that between identically made sensors is <5%, suggesting mass production techniques without individual calibration will be acceptable for all but the most demanding situation.
9 citations
TL;DR: In this paper, the authors focus on near real-time analysis of ionic constituents in atmospheric aerosol and other approaches to aerosol composition measurement are also briefly covered, including particle mass spectrometry (MS) techniques.
Abstract: Publisher Summary This chapter focuses on near real-time analysis of ionic constituents in atmospheric aerosol. Other approaches to aerosol composition measurement are also briefly covered. The demand for (near) real-time aerosol composition measurement has never been greater. While the focus of this chapter has been primarily on ambient outdoor air measurement, there is already worldwide desire to find an effective means of infective bioaerosol detection. Fundamental investigations in both stratospheric and tropospheric chemistry will likely be dominated in the future by particle mass spectrometry (MS) techniques. On the other hand, near real-time systems that integrate collection and can measure a broad suite of substances at one time (by chromatography or chromatography-MS techniques) holds much promise in regulatory, epidemiological and toxicological applications and more routine measurements.
9 citations
Patent•
23 Aug 2012TL;DR: In this article, the buffer generators are described based on electrodialytic devices and the methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography.
Abstract: Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.
9 citations
TL;DR: Perceptible current flow and KOH production in the BPM-based EG begins at subelectrolytic applied voltages, prompting us to look more closely at exact field strength necessary for field-enhanced dissociation of water.
Abstract: A gas-free KOH eluent generator (EG) with 210 nL of internal volume is described. It utilizes a two-membrane configuration where there is a single CEM layer on one side and a single BPM layer on th...
9 citations
TL;DR: The feasibility of determining aqueous ozone by chemiluminescence flow-injection analysis (CL-FIA) was studied for applications in potable water treatment and significant discrimination against the interferents is possible by taking advantage of the much faster kinetics of the CL reaction with ozone.
9 citations
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TL;DR: The manipulation of fluids in channels with dimensions of tens of micrometres — microfluidics — has emerged as a distinct new field that has the potential to influence subject areas from chemical synthesis and biological analysis to optics and information technology.
Abstract: The manipulation of fluids in channels with dimensions of tens of micrometres--microfluidics--has emerged as a distinct new field. Microfluidics has the potential to influence subject areas from chemical synthesis and biological analysis to optics and information technology. But the field is still at an early stage of development. Even as the basic science and technological demonstrations develop, other problems must be addressed: choosing and focusing on initial applications, and developing strategies to complete the cycle of development, including commercialization. The solutions to these problems will require imagination and ingenuity.
8,260 citations
TL;DR: It is reported that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools.
Abstract: Nanoparticles containing magnetic materials, such as magnetite (Fe3O4), are particularly useful for imaging and separation techniques. As these nanoparticles are generally considered to be biologically and chemically inert, they are typically coated with metal catalysts, antibodies or enzymes to increase their functionality as separation agents. Here, we report that magnetite nanoparticles in fact possess an intrinsic enzyme mimetic activity similar to that found in natural peroxidases, which are widely used to oxidize organic substrates in the treatment of wastewater or as detection tools. Based on this finding, we have developed a novel immunoassay in which antibody-modified magnetite nanoparticles provide three functions: capture, separation and detection. The stability, ease of production and versatility of these nanoparticles makes them a powerful tool for a wide range of potential applications in medicine, biotechnology and environmental chemistry.
4,500 citations
TL;DR: The ability of DLLME technique in the extraction of other organic compounds such as organochlorine pesticides, organophosphorus pesticides and substituted benzene compounds were studied.
2,959 citations
TL;DR: It is concluded that when nonmonotonic dose-response curves occur, the effects of low doses cannot be predicted by the effects observed at high doses, and fundamental changes in chemical testing and safety determination are needed to protect human health.
Abstract: For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional concepts in toxicology, in particular the dogma of “the dose makes the poison,” because EDCs can have effects at low doses that are not predicted by effects at higher doses. Here, we review two major concepts in EDC studies: low dose and nonmonotonicity. Low-dose effects were defined by the National Toxicology Program as those that occur in the range of human exposures or effects observed at doses below those used for traditional toxicological studies. We review the mechanistic data for low-dose effects and use a weight-of-evidence approach to analyze five examples from the EDC literature. Additionally, we explore nonmonotonic dose-response curves, defined as a nonlinear relationship between dose and effect where the slope of the curve changes sign somewhere within the range of doses examined. We provide a detailed discussion of the mechanisms responsible for generating these phenomena, plus hundreds of examples from...
2,475 citations
Brigham and Women's Hospital1, Boston University2, University of California, Los Angeles3, Boston Children's Hospital4, University of Alabama at Birmingham5, Stanford University6, Northwestern University7, Aalborg University8, Cardiff University9, University of Pennsylvania10, Erasmus University Rotterdam11, Medical University of South Carolina12
TL;DR: The revised guidelines for the management of thyroid disease in pregnancy include recommendations regarding the interpretation of thyroid function tests in pregnancy, iodine nutrition, thyroid autoantibodies and pregnancy complications, thyroid considerations in infertile women, hypothyroidism in pregnancy and thyrotoxicosis in pregnancy.
Abstract: Background: Thyroid disease in pregnancy is a common clinical problem. Since the guidelines for the management of these disorders by the American Thyroid Association (ATA) were first published in 2...
2,409 citations