Author
Qian Wang
Bio: Qian Wang is an academic researcher from Xuzhou Medical College. The author has contributed to research in topics: Dimedone & One-pot synthesis. The author has an hindex of 7, co-authored 28 publications receiving 160 citations.
Topics: Dimedone, One-pot synthesis, Pyridine, Aldehyde, Malononitrile
Papers
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TL;DR: In this article, four-component cyclocondensation of aromatic aldehydes, malononitrile, dimedone and ammonium acetate proceeds under microwave irradiation in solvent free conditions to give highly functionalized hexahydroquinolines.
27 citations
TL;DR: Triaza-benzo[b]fluoren-6-one derivatives were synthesized via the three-component reaction of aldehyde, cyclohexane-1,3-dione compound and 2-aminobenzimidazole in water under microwave irradiation as discussed by the authors.
24 citations
TL;DR: In this article, a series of furo[3,4-e]pyrazolo[ 3,4b]pyridine analogues of podophylloxin were synthesized via three-component reactions of aldehydes, 3-methyl-1-phenyl-1H-pyrazol-5-amine and tetronic acid in water under microwave irradiation without catalyst.
21 citations
TL;DR: A series of bifunctional compounds containing two pyrazolo[3,4-b]pyridine moieties has been synthesized through a rapid one-pot three-component reaction of dialdehyde, 5-amino-3-methyl-1-phenylpyrazole and active methylene compounds in glycol under microwave irradiation without catalyst.
19 citations
TL;DR: A series of new N-cyclopropyldecahydroacridine derivatives were synthesized by one-pot reaction of aromatic aldehyde, dimedone (or 1,3-cyclohexanedione) and cyclopropanamine in solution of glycol and water under microwave irradiation with excellent yields (78-94%) and short reaction time (5-10 min) as mentioned in this paper.
16 citations
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386 citations
TL;DR: Recent advances on multicomponent domino reactions for the construction of five-, six-, and seven-membered heterocyclic skeletons and their multicyclic derivatives are covered.
Abstract: Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one-pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of starting materials, and the use of energy and manpower. Moreover, the reaction period can be substantially shortened. This Review covers recent advances on multicomponent domino reactions for the construction of five-, six-, and seven-membered heterocyclic skeletons and their multicyclic derivatives.
355 citations
TL;DR: In this article, a four-component reaction of aldehydes, dimedone, active methylene compounds, and ammonium acetate in one-pot under solvent-free conditions at room temperature on grinding is described.
152 citations
TL;DR: Natural and synthetic acridine/acridone analogs, their application as anticancer drugs and methods for their preparation are reviewed.
136 citations
TL;DR: This review provides a concise overview of new dimensions of green chemistry approaches in designing quinoline scaffold that would encourage the researchers towards green chemistry as well as future application of these greener, non-toxic, environment friendly methods.
121 citations