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Qian Yang

Researcher at Fourth Military Medical University

Publications -  53
Citations -  8687

Qian Yang is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Autophagy & Chaperone-mediated autophagy. The author has an hindex of 25, co-authored 47 publications receiving 7039 citations. Previous affiliations of Qian Yang include Emory University & Guangzhou Medical University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy

TL;DR: It is found that chaperone-mediated autophagy regulated the activity of myocyte enhancer factor 2D (MEF2D), a transcription factor required for neuronal survival, and dysregulation of this pathway is associated with Parkinson's disease.
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Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

TL;DR: It is shown that Cdk5 (cyclin-dependent kinase 5), activated by DNA damage, directly phosphorylates ATM at Ser 794 in post-mitotic neurons, providing a critical signal to initiate the ATM response and regulate ATM-dependent cellular processes.
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Control of MEF2 Transcriptional Activity by Coordinated Phosphorylation and Sumoylation

TL;DR: An essential role for Ser-444 is identified in MEF2D sumoylation and a novel mechanism by which calcineurin selectively “edits” phosphorylation at different sites is revealed, thereby reiterating that interplay between different modifications represents a general mechanism for coordinated regulation of eukaryotic protein functions in vivo.