R.G. Busnel

TL;DR: The results suggest that HIV inactivation is dependent on the viral concentration, the time of incubation in presence of the putative disinfectant and the degree of virucidal activity of the latter.

TL;DR: Hypochlorous acid proved to exert a rapid inhibitory effect on DNA synthesis, consistent with its primary role in bacterial killing by phagocytes, and Cytotoxicity produced by increasing NaOCl concentrations and assessed by measuring both mitochondrial function and cell DNA synthesis was reduced.

TL;DR: Chloramines are selective and stable chemical generators of hypochlorite and chloramines and are both a signal and a weapon with therapeutic potency against very different pathogens, such as microbes, virus, cancer cells and thrombi.

TL;DR: Protocols to measure the efficacy of alcohols against HIV in suspension and dried onto surfaces in the presence of high and low protein concentrations showed that high titres of HIV in suspended form were rapidly inactivated by 70% ethanol, independent of the protein load.

TL;DR: The protocol changes established by the authors to prepare lyophilized bovine cancellous bone at a semi-industrial scale is reproducible and yielded a product with excellent biocompatibility.

TL;DR: A range of commercially available disinfectants with active constituents including glutaraldehyde, chlorine, phenolics, alcohol, iodine and quaternary ammonium compounds was tested, finding cell-associated HIV was more resilient than cell-free HIV and the effectiveness of the disinfectants was further compromised in the presence of blood.