R
Rachel Brown
Researcher at University College London
Publications - 17
Citations - 1005
Rachel Brown is an academic researcher from University College London. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 12 publications receiving 581 citations. Previous affiliations of Rachel Brown include University College London Hospitals NHS Foundation Trust & UCL Institute of Neurology.
Papers
More filters
Journal ArticleDOI
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings.
Ross W. Paterson,Ross W. Paterson,Rachel Brown,Laura A Benjamin,Laura A Benjamin,Ross Nortley,Ross Nortley,Sarah Wiethoff,Sarah Wiethoff,Tehmina Bharucha,Tehmina Bharucha,Tehmina Bharucha,Dipa L Jayaseelan,Dipa L Jayaseelan,Guru Kumar,Rhian E Raftopoulos,Laura Zambreanu,Laura Zambreanu,Vinojini Vivekanandam,Anthony Khoo,Ruth Geraldes,Ruth Geraldes,Krishna Chinthapalli,Krishna Chinthapalli,Elena Boyd,Hatice Tuzlali,Gary Price,Gerry Christofi,Jasper M. Morrow,Jasper M. Morrow,Patricia McNamara,Benjamin C Mcloughlin,Soon Tjin Lim,Puja Mehta,Viva Levee,Stephen Keddie,Wisdom Yong,S Anand Trip,S Anand Trip,Alexander J.M. Foulkes,Alexander J.M. Foulkes,Gary Hotton,Thomas D. Miller,Alex Everitt,Christopher Carswell,Nicholas W. S. Davies,Michael Yoong,David Attwell,Jemeen Sreedharan,Eli Silber,Jonathan M. Schott,Arvind Chandratheva,Richard J. Perry,Robert Simister,Anna M. Checkley,Nicky Longley,Simon F. Farmer,Francesco Carletti,Catherine F Houlihan,Maria Thom,Michael P. Lunn,Jennifer Spillane,Jennifer Spillane,Robin Howard,Robin Howard,Angela Vincent,Angela Vincent,David J. Werring,Chandrashekar Hoskote,Hans Rolf Jäger,Hans Rolf Jäger,Hadi Manji,Hadi Manji,Michael S. Zandi,Michael S. Zandi +74 more
TL;DR: A case series of 43 patients with neurological complications of SARS-CoV-2 infection includes encephalopathies, encephalitis, acute disseminated encephalomyelitis with haemorrhagic change, transverse myelitis, ischaemic stroke, and Guillain-Barré syndrome.
Journal ArticleDOI
Early detection of melanoma metastases with radioiodinated methylene blue
Eva M. Link,Philip J. Blower,Durval C. Costa,David Lane,D. Lui,Rachel Brown,Peter J. Ell,M F Spittle +7 more
TL;DR: This first clinical investigation concerning the diagnostic potential of radioiodinated MTB in patients with disseminated melanoma confirmed the existence of approximately 80% of internal lesions previously identified by routine methods and enabled detection of unknown secondaries in 6 of 12 patients studied.
Journal ArticleDOI
Serum and cerebrospinal fluid biomarker profiles in acute SARS-CoV-2-associated neurological syndromes
Ross W. Paterson,Ross W. Paterson,Ross W. Paterson,Laura A Benjamin,Puja Mehta,Rachel Brown,Rachel Brown,Dilan Athauda,Dilan Athauda,Nicholas J. Ashton,Nicholas J. Ashton,Claire A Leckey,Claire A Leckey,Oliver J. Ziff,Judith Heaney,Amanda Heslegrave,Amanda Heslegrave,Andrea L Benedet,Kaj Blennow,Anna M. Checkley,Catherine F Houlihan,Catherine F Houlihan,Catherine J. Mummery,Catherine J. Mummery,Michael P. Lunn,Michael P. Lunn,Hadi Manji,Michael S. Zandi,Michael S. Zandi,Stephen Keddie,Stephen Keddie,Michael Chou,Michael Chou,Deepthi Vinayan Changaradil,Tom Solomon,Tom Solomon,Ashvini Keshavan,Ashvini Keshavan,Suzanne Barker,Suzanne Barker,Hans Rolf Jäger,Hans Rolf Jäger,Francesco Carletti,Francesco Carletti,Robert Simister,Robert Simister,David J. Werring,David J. Werring,Moira J. Spyer,Eleni Nastouli,Serge Gauthier,Pedro Rosa-Neto,Henrik Zetterberg,Henrik Zetterberg,Jonathan M. Schott,Jonathan M. Schott +55 more
TL;DR: This article found increased concentrations of neurofilament light, a dynamic biomarker of neuronal damage, in the CSF of patients with COVID-19 and characterized neurological syndromes involving the PNS and CNS.
Journal ArticleDOI
Mutation of TBCK causes a rare recessive developmental disorder.
TL;DR: All affected siblings share homozygosity for a novel 4-bp deletion in the gene TBCK, providing the genetic cause of a severe inherited disease in a family and extending the number of mutations and phenotypes associated with this recently identified disease gene.
Journal ArticleDOI
Amyloid processing in COVID‐19‐associated neurological syndromes
Oliver J. Ziff,Nicholas J. Ashton,Puja Mehta,Rachel Brown,Dilan Athauda,Judith Heaney,Amanda Heslegrave,Andrea Lessa Benedet,Kaj Blennow,Anna M. Checkley,Catherine F Houlihan,Serge Gauthier,Pedro Rosa-Neto,Nick C. Fox,Jonathan M. Schott,Henrik Zetterberg,Laura A Benjamin,Ross W. Paterson +17 more
TL;DR: Altered amyloid processing was linked to neuronal injury and neuroinflammation but reduced astrocyte activation and a sensitivity analysis of COVID‐19‐associated GBS revealed a non‐significant trend toward greater impairment of amyloids processing in CO VID‐19 central than peripheral neurological syndromes.