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Rachna Khosla Sardana

Bio: Rachna Khosla Sardana is an academic researcher from Lovely Professional University. The author has contributed to research in topics: Cancer & Adenocarcinoma. The author has an hindex of 1, co-authored 1 publications receiving 32 citations.

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TL;DR: Most of the studies show a positive correlation of esophageal cancer with alcohol and tobacco consumption, but a negative correlation with fruit and vegetable intake, and significant statistical synergistic interaction has been registered in studies considering the joint effect of the amount of beverage swallowed and its temperature.
Abstract: Cancer is the abnormal growth of cells that tend to proliferate in an uncontrolled way. About 32.6 million people in the world are affected by different types of cancer; 456 000 have esophageal cancer, which is the eighth most common cancer and the sixth most common cause of cancer-related deaths with a toll of 400 000 in 2012. About 80% of cases were reported from the less developed regions of the world. An incidence ratio of 2.4 : 1 for men and women reveals the gender disparity. Esophageal cancer is mainly of two types, namely, squamous cell carcinoma and adenocarcinoma. Most of the studies show a positive correlation of esophageal cancer with alcohol and tobacco consumption, but a negative correlation with fruit and vegetable intake. The type and amount of cereal, fat, meat and beverages consumed are also under study. Significant statistical synergistic interaction has been registered in studies considering the joint effect of the amount of beverage swallowed and its temperature, especially among heavy consumers. The role of non-nutritional components is gaining increasing attention because of their antioxidant, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties. Socioeconomic status is another factor that cannot be ignored. Nevertheless, the predominant cause appears to be different in different regions, and in spite of the great advancements in the medical field, this still remains an enigma for researchers.

46 citations


Cited by
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Journal ArticleDOI
TL;DR: Overall objective of this review is to provide a brief knowledge about the valuable phytochemicals and bioactive compounds present in beetroot and their association with health benefits, beetroot processing for food application and their effect on beetroot pigment.

249 citations

Journal ArticleDOI
TL;DR: The present review explores the nutritional, phytochemical and pharmacological potential as well as diverse food usages of Syzygium cumini, a traditional medicinal plant with various bioactive compounds distributed in all parts of the plant.
Abstract: The present review explores the nutritional, phytochemical and pharmacological potential as well as diverse food usages of Syzygium cumini. S. cumini is a traditional medicinal plant with various bioactive compounds distributed in all parts of the plant. The major bioactive compounds present in the edible part are myricetin, oxalic acid, gallic acid, citronellol, cyanidin diglucoside, hotrienol, phytosterols, flavonoids, carotenoids and polyphenols as well as micronutrients, accounting for numerous health benefits. The potential benefits of these bioactive compounds are to prevent/reduce metabolic abnormalities and various diseases. The health protective effects and functional properties of the plant were proved by different in vitro and in vivo pharmacological studies. All parts of the plant have good health benefits like hypoglycemic, anti-inflammatory, antianemic, antibacterial, antioxidant, antiallergic, hepatoprotective, hypolipidemic and antipyretic properties. The fruit of S. cumini can be consumed raw or processed in the form of jam, jellies, wine, fermented beverages and many other value added food products.

79 citations

Journal ArticleDOI
TL;DR: Parkia speciosa is considered as one of the highly underutilized plants with multidimensional utility and benefits as mentioned in this paper, and the nutritional composition of the seeds is substantial with rich proteins (6.0-27.5%), fats (1.6-13.3%), carbohydrates (68.3-68.7%), minerals (0.5-0.8%), and fibers (17-2.0%).
Abstract: The plant community comprises certain underutilized plant species which has proven to be beneficial to human health. Parkia speciosa is considered as one of the highly underutilized plants with multidimensional utility and benefits. The nutritional composition of the seeds is substantial with rich proteins (6.0–27.5%), fats (1.6–13.3%), carbohydrates (68.3–68.7%), minerals (0.5–0.8%) and fibers (1.7–2.0%). Edible part (100 g) contains essential minerals like calcium (108–265.1 mg), magnesium (29 mg), potassium (341 mg), phosphorous (115 mg), and iron (2.2–2.7 mg) required for different metabolic reactions in human body. Bioactive compounds like phenols [51.9–84.24 mg Gallic acid equivalent (GAE)/g], flavonoids [47.4–49.6 mg retinol equivalent (RE)/100 g on dry weight basis], terpenoids like β-sitosterol (3.42% of fatty acid content), stigmasterol (2.18% of fatty acid content), lupeol (0.71% of fatty acid content), campesterol (2.29% of fatty acid content) are also present. These bioactive compounds and peptides possess different medicinal properties like anti-hypertensive, antioxidative, anti-inflammatory, anticancer, anti-microbial activity and antinociceptive. P. speciosa is traditionally consumed as vegetable, salad and in boiled form. Rich nutrient value and photochemistry suggest that there is tremendous need of scientific work to explore its food utilization. The review describes nutritional, phytochemical compound and the potential of P. speciosa for functional food formulation.

49 citations

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TL;DR: The nutritional and food value of pumpkin Cucurbita, along with different health benefits, are reviewed, to highlight the nutritional, therapeutic, potential and processing attributes.
Abstract: The purpose of this paper is to review the nutritional and food value of pumpkin Cucurbita, along with different health benefits. Cucurbita (pumpkin) is an herbaceous vine, member of Cucurbitaceae family. It is an edible, heat-sensitive plant, which has an abundant amount of active compounds such as carotenoids, alkaloids, flavonoids, polyphenols, tannins, tocopherols, phytosterols and cucurbitacin, accounted for numerous health benefits, namely, antidiabetic, antioxidant, anticarcinogenic, hypotensive, hyper protective activities.,Major well-known bibliometric information sources such as Web of Science, Scopus, Mendeley and Google Scholar were searched with keywords such as nutrition value of Cucurbita, Cucurbita utilization, bioactive compounds of pumpkin, health benefits, processing, food formulations and current scenarios were chosen to obtain a large range of papers to be analyzed. A final inventory of 105 scientific sources was made after sorting and classifying them according to different criteria based on topic, academic field, country of origin and year of publication.,The comprehensive review of different literature, data sources and research papers seeks to find and discuss various nutritional benefits of pumpkin. It contains all necessary macro- and micro-nutrients, amino acids, vitamins, antioxidants and bioactive compounds with a relatively low amount of antinutrients. The recent upsurge in consumer interest for health-promoting products has opened up new vistas for plant products containing bioactive compounds in different food formulations.,This paper contains information regarding the chemical composition, nutritive value, phytochemical studies, pharmacological properties, bio-accessibility, food and industrial applications of pumpkin. Worldwide, pumpkin is used as food additive in various food products such as candy, weaning mix, corn grits, kheer, jam, crackers, bread, etc. Effect of different processing methods such as high temperature, pH, blanching, oven drying, freeze-drying to retain or minimize its losses in case of color, texture, flavor, and the carotenoids are of concern. The review paper highlights the nutritional, therapeutic, potential and processing attributes.

37 citations

Journal ArticleDOI
TL;DR: Overall, the clinical data compiled on phytochemicals against EC is not sufficient and need future research to provide additional insights for developing potential anticancer drugs in pharma industries.

37 citations