R
Radjendirane Venugopal
Researcher at University of Texas System
Publications - 4
Citations - 1105
Radjendirane Venugopal is an academic researcher from University of Texas System. The author has contributed to research in topics: Gene expression & Caffeic acid. The author has an hindex of 2, co-authored 4 publications receiving 1057 citations. Previous affiliations of Radjendirane Venugopal include Fox Chase Cancer Center.
Papers
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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
TL;DR: It is reported here that Jun, Fos, Fra, and NRF nuclear transcription factors bind to the hARE, indicating that hARE-mediated expression of the NQO1 gene and its induction by xenobiotics and antioxidants are mediated by Nrf1 and Nrf2.
Journal Article
Caffeic acid phenethyl ester stimulates human antioxidant response element-mediated expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene.
TL;DR: It is determined by Northern analysis that CAPE treatment of hepatoma cells stimulates NQO1 gene expression in cultured human hepatomas cells (HepG2), and the effects ofCAPE treatment on the expression of a reporter gene either containing or lacking the hARE or carrying a mutant version of this element in rodent hepatoma (H Hepa-1) transfectants are characterized.
Patent
Caffeic acid derivatives and uses thereof
Waldemar Priebe,Skora Stanislaw,Fokt Izabela,Rafal Zielinski,Jayakumar Arumugam,Radjendirane Venugopal +5 more
TL;DR: In this paper, the authors present pharmaceutical compositions and methods of using of the compounds disclosed herein, including for the treatment of cancer, in another aspect, the present disclosure provides pharmaceutical compositions.
Patent
Caffeic acid derivatives for treating hyperproliferative diseases
Waldemar Priebe,Skora Stanislaw,Fokt Izabela,Rafal Zielinski,Jayakumar Arumugan,Radjendirane Venugopal +5 more
TL;DR: In this paper, the authors present a disclosure of the composition and methods of using of the compounds disclosed herein, including for the treatment of cancer, for the purpose of providing pharmaceutical compositions and methods for using the compounds.