Raghavendra M Shetty

Bio: Raghavendra M Shetty is an academic researcher from Gulf Medical University. The author has contributed to research in topics: Medicine & Maxillary central incisor. The author has an hindex of 10, co-authored 44 publications receiving 243 citations. Previous affiliations of Raghavendra M Shetty include Nitte University.

An in-vitro evaluation of the efficacy of garlic extract as an antimicrobial agent on periodontal pathogens: A microbiological study.

Abstract: With the rise in bacterial resistance to antibiotics, there is considerable interest in the development of other classes of antimicrobials for the control of infection. Garlic (Allium sativum Linn.) has been used as medicine since ancient times and has long been known to have antibacterial, antifungal, and antiviral properties. This study was undertaken to assess the inhibitory effect of garlic on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, to assess the time-kill curve of P. gingivalis and A. actinomycetemcomitans, and to determine the antiproteolytic activity of garlic on P. gingivalis. Ethanolic garlic extract (EGE) and aqueous garlic extract (AGE) were prepared and the inhibitory effects of these extracts for two periodontal pathogens (P. gingivalis and A. actinomycetemcomitans) were tested. Antiproteolytic activity on protease of P. gingivalis was determined. 25 microliter (μl), 50 μl, and 75 μl of AGE showed 16 mm, 20 mm, and 25 mm zone of inhibition, respectively, on P. gingivalis. The AGE showed greater bacteriostatic activity against the P. gingivalis with minimum inhibitory concentration determined at 16.6 μl/ml. The time-kill assay of AGE and EGE were compared for P. gingivalis and A. actinomycetemcomitans. AGE showed better antiproteolytic activity on total protease of P. gingivalis compared to the EGE. Thus, the study concludes the antimicrobial activity of garlic extract against periodontal pathogens, P. gingivalis, A. actinomycetemcomitans. Its action against P. gingivalis includes inhibition of total protease activity, and this raises the possibility that garlic may have therapeutic use for periodontitis and possibly other oral infections.

RMS Pictorial Scale (RMS-PS): an innovative scale for the assessment of child's dental anxiety.

Abstract: Background: Dental anxiety assessment for young children is as important as performing their treatment. Appropriate knowledge of patient's anxiety boosts confidence and will help us to review potential management options specific to every child. Aim: This study aimed to validate (RMS) Pictorial Scale (RMS-PS) and to compare it with Venham Picture Test (VPT) and Facial image scale (FIS) in measuring dental anxiety for young children during their first dental visit. Materials and Methods: A total of 102 healthy children aged between 4 and 14 years during their first dental visit were randomly selected for the study. Childs anxiety level was measured using three different scales namely (i) RMS-PS (ii) VPT, and (iii) FIS. Statistical Analysis: Student t test was used to compare the scores obtained from all the three scales. Pearson correlation test was used to obtain correlation among the scales used in the study. Results: A strong correlation (0·76) was found between the VPT and RMS-PS, and a moderate correlation (0.5) was found between RMS-PS and FIS, indicating good validity for the RMS-PS. Conclusions: The findings of this study suggest that the RMS-PS can be a newer and easiest means for the assessment of dental anxiety for young children in a clinical context.

Comparison of soft-tissue, dental, and skeletal characteristics in children with and without tongue thrusting habit

Abstract: Background: Tongue thrusting habit is a condition in which the tongue makes contact with any teeth anterior to the molars during swallowing. Abnormal positioning of tongue may result in dental and skeletal abnormalities. Objective: The aim of the present study was to study and compare soft-tissue, dental, and skeletal morphologic characteristics in children with and without tongue thrusting habit. Materials and Methods: A total of 21 children with tongue thrusting habit and 21 children without any habit between age 10 and 14 years were selected for the study. Various soft-issue, dental and cephalometric parameters were measured and compared statistically. Results: Significantly, higher number of children with tongue thrusting showed lip incompetency (86% vs. 14%), mouth-breathing habit (38% vs. none), hyperactive mentalis muscle activity (24% vs. none), Open-bite (52% vs. none) and lisping (86% vs. none) when compared to children without tongue thrust. Children with tongue thrust showed increased upper lip thickness and proclination of maxillary incisors No differences were found in angulation of mandibular incisors, inter-premolar or inter-molar widths and all the skeletal parameters studied. Conclusions: Tongue thrust seemed to affect some of the soft-tissue and dental characteristics causing lip incompetency, mouth-breathing habit, and hyperactive mentalis muscle activity, lisping, open-bite, and proclination of maxillary incisors; however, no significant skeletal changes were observed.

Influence of mother's oral health care knowledge on oral health status of their preschool child

Abstract: Aim: Children under 5 years of age generally spend most of their time with parents or guardians, especially mothers. Parents play a central role in giving children the information and encouragement needed for healthy lives. Parental oral health knowledge, belief and attitudes influence the oral health maintenance, dietary habits and healthy behavior of their children. The aim of this study was to assess the mothers oral health care knowledge and to assess the oral health status of their child. Materials and Methods: A total of 386 mothers along with their child of 1-6 years were randomly selected for the study. A 22-point questionnaire including parent's literacy levels, socioeconomic status, dietary practices and oral hygiene practices, was designed to assess the knowledge of the mothers regarding oral health of their child. Oral examination of the children was done by World Health Organization criteria for recording children's oral health status. Results: About 87% of the mothers agreed that intake of food with excessive sugars can cause cavities, and 95.8% admitted that chocolates cause the most decay. 80.5% agreed to the fact that leaving a milk bottle all night increases the risk for tooth decay, however, 59.3% mothers were of the opinion that dental visit is must only in the presence of decay. 59.3% mothers were unaware about the optimal fluoride content. 71.7% mothers agreed that caries in deciduous teeth are a matter of concern. The average decayed score of the children was 2.9 and 77.9% of the children had a fair to good oral hygiene status. Conclusion: Instead of the fact that most of the health care knowledge that the mothers had was primarily from the family elders, they were aware of caries risk factors, tooth brushes and amount of toothpaste and bacteria from mother's cavities can infect child. This could be observed by less number of decayed teeth and good oral hygiene status of the children. However, parents knowledge, attitudes and few beliefs regarding dental care need to be improved.

Unicystic ameloblastoma, a prognostically distinct entity

Abstract: The occurrence of unicystic ameloblastoma has been studied in 20 patients presenting with unilocular cystic lesions whose clinical, radiographic and gross features were those on non-neoplastic cysts. In the majority of these, the lesion mimicked dentigerous cyst. The rate of recurrence for this group of lesions as determined by long term follow-up observation available for the majority of patients was distinctly lower than that associated with multicystic character of the lesion throughout its course, is indicative of a much less aggressive variety of neoplasm. The adequacy of simple enucleation as a modality of treatment in the majority of patients with this type of lesion is suggested. It was not possible to answer the question whether or not the ameloblastoma began in antecedent non-neoplastic cyst.

Common dental diseases in children and malocclusion

Abstract: Malocclusion is a worldwide dental problem that influences the affected individuals to varying degrees. Many factors contribute to the anomaly in dentition, including hereditary and environmental aspects. Dental caries, pulpal and periapical lesions, dental trauma, abnormality of development, and oral habits are most common dental diseases in children that strongly relate to malocclusion. Management of oral health in the early childhood stage is carried out in clinic work of pediatric dentistry to minimize the unwanted effect of these diseases on dentition. This article highlights these diseases and their impacts on malocclusion in sequence. Prevention, treatment, and management of these conditions are also illustrated in order to achieve successful oral health for children and adolescents, even for their adult stage.

Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms

Abstract: Oral diseases such as caries and periodontitis are mainly caused by microbial biofilms. Antibiotic therapy has reached its limits with regard to antimicrobial resistance, and new therapeutic measures utilizing natural phytochemicals are currently a focus of research. Hence, this systematic review provides a critical presentation of the antimicrobial effects of various medicinal herbs against in vitro, ex vivo, and in situ formed multispecies oral biofilms. Searches were performed in three English databases (PubMed, EMBASE, CAMbase) and the electronic archives of five German journals from the times of their establishment until October 10th, 2014, with the search terms "(plant extracts OR herbal extracts OR plant OR herb) AND (oral biofilm OR dental biofilm OR dental plaque OR oral disease OR dental disease)." The pooled data were assessed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA). Initially, 1848 articles were identified, out of which 585 full-text articles were screened, 149 articles were reevaluated for eligibility and finally, 14 articles met all inclusion criteria. The data of 14 reports disclosed enhanced antiadhesive and antibiofilm activity by the plant extracts obtained from Vitis vinifera, Pinus spp., Coffea canephora, Camellia sinensis, Vaccinium macrocarpon, Galla chinensis, Caesalpinia ferrea Martius, Psidium cattleianum, representative Brazilian plants and manuka honey. Overall, a positive correlation was revealed between herb-based therapies and elimination rates of all types of multispecies oral biofilms. In that context, integrating or even replacing conventional dental therapy protocols with herbal-inspired treatments can allow effective antimicrobial control of oral biofilms and thus, dental diseases.