R
Rajesh K. Grover
Researcher at Scripps Research Institute
Publications - 28
Citations - 1383
Rajesh K. Grover is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Protein M & Cancer. The author has an hindex of 15, co-authored 28 publications receiving 1253 citations. Previous affiliations of Rajesh K. Grover include Central Drug Research Institute.
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Mechanism of thioflavin T binding to amyloid fibrils
Ritu Khurana,Chris Coleman,Cristian Ionescu-Zanetti,Sue A. Carter,Vinay Krishna,Rajesh K. Grover,Raja Roy,Shashi Singh +7 more
TL;DR: The data suggests that the micelles of thioflavin T bind amyloid fibrils leading to enhancement of fluorescence emission, which suggests that positive charge on the thioFlavin T molecule has a role in its micelle formation that then bind the amyloids fibril.
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A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Rajesh K. Grover,Xueyong Zhu,Travis Nieusma,Teresa M. Jones,Isabel Boero,Amanda S. MacLeod,Adam Mark,Sherry Niessen,Helen J. Kim,Leopold Kong,Nacyra Assad-Garcia,Keehwan Kwon,Marta Chesi,Vaughn V. Smider,Daniel R. Salomon,Diane F. Jelinek,Robert A. Kyle,Richard B. Pyles,John I. Glass,Andrew B. Ward,Ian A. Wilson,Richard A. Lerner +21 more
TL;DR: The crystal structure of Protein M revealed how Protein-M binding blocks the antibody's antigen binding site, and may be exploited by mycoplasma to escape the humoral immune response.
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CYP 1A1 polymorphism and organochlorine pesticides levels in the etiology of prostate cancer.
Vivek Kumar,Chandra Shekhar Yadav,Satyender Singh,Sanjay Goel,Rafat S. Ahmed,Sanjay Gupta,Rajesh K. Grover,Basu Dev Banerjee +7 more
TL;DR: Higher level of OCPs, especially β-H CH, γ-HCH and p,p'-DDE might be associated with prostate cancer risk, and any correlation between prostate cancer and CYP1A1 polymorphisms is not observed.
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Identification of Specific miRNA Signature in Paired Sera and Tissue Samples of Indian Women with Triple Negative Breast Cancer.
TL;DR: An extremely high prevalence of TNBC in premenopausal women below 35 years of age and a significant altered expression of a panel of three specific oncogenic and three tumor suppressor miRNAs in both tissues and corresponding sera of T NBC patients when compared with triple positive breast cancer (TPBC) patients are reported for the first time.
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Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal
Julong Cheng,Ali Torkamani,Rajesh K. Grover,Teresa M. Jones,Diana I. Ruiz,Nicholas J. Schork,Michael M. Quigley,F. Wesley Hall,Daniel R. Salomon,Richard A. Lerner +9 more
TL;DR: It is reported here that the immunoglobulin repertoires of these infiltrating B cells are highly restricted and the B cells within a cluster are clonal.