Rajesh Kumar

Bio: Rajesh Kumar is an academic researcher from Himachal Pradesh University. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 149, co-authored 4439 publications receiving 140830 citations. Previous affiliations of Rajesh Kumar include Guru Nanak Dev University & Intuitive Surgical.

UV-activated MoS2 Based Fast and Reversible NO2 Sensor at Room Temperature

Abstract: Two-dimensional materials have gained considerable attention in chemical sensing owing to their naturally high surface-to-volume ratio. However, the poor response time and incomplete recovery at room temperature restrict their application in high-performance practical gas sensors. Herein, we demonstrate ultrafast detection and reversible MoS2 gas sensor at room temperature. The sensor’s performance is investigated to NO2 at room temperature, under thermal and photo energy. Incomplete recovery and high response time of ∼249 s of sensor are observed at room temperature. Thermal energy is enough to complete recovery, but it is at the expense of sensitivity. Further, under photo excitation, MoS2 exhibits an enhancement in sensitivity with ultrafast response time of ∼29 s and excellent recovery to NO2 (100 ppm) at room temperature. This significant improvement in sensitivity (∼30%) and response time (∼88%) is attributed to the charge perturbation on the surface of the sensing layer in the context of NO2/MoS2 i...

Brief report: inhibition of renal phosphate transport by a tumor product in a patient with oncogenic osteomalacia.

Abstract: In tumor-induced osteomalacia, a rare syndrome characterized by hypophosphatemia, hyperphosphaturia, low plasma 1,25-dihydroxyvitamin D concentrations, and osteomalacia,1–5 all biochemical and pathological abnormalities disappear when the tumor is removed. Tumors associated with this syndrome are thought to secrete a substance that inhibits the renal tubular reabsorption of phosphate,1–5 but whether this factor interacts directly with renal tubular cells is not known. We investigated the ability of medium in which sclerosing hemangioma cells from a patient with oncogenic osteomalacia were cultured to alter sodium-dependent phosphate transport in opossum-kidney epithelial cells. We found that the medium inhibited phosphate transport, without increasing . . .

Measurement of J/psi production in pp collisions at root s=7 TeV

Abstract: The production of J/psi mesons in proton-proton collisions at root s = 7 TeV is studied with the LHCb detector at the LHC. The differential cross-section for prompt J/psi production is measured as a function of the J/psi transverse momentum p(T) and rapidity y in the fiducial region p(T) is an element of [0; 14] GeV/c and y is an element of [2.0; 4.5]. The differential cross-section and fraction of J/psi from b-hadron decays are also measured in the same p(T) and y ranges. The analysis is based on a data sample corresponding to an integrated luminosity of 5.2 pb(-1). The measured cross-sections integrated over the fiducial region are 10.52 +/- 0.04 +/- 1.40(-2.20)(+1.64) mu b for prompt J/psi production and 1.14 +/- 0.01 +/- 0.16 mu b for J/psi from b-hadron decays, where the first uncertainty is statistical and the second systematic. The prompt J/psi production cross-section is obtained assuming no J/psi polarisation and the third error indicates the acceptance uncertainty due to this assumption.

Prospective Study of One Million Deaths in India: Rationale, Design, and Validation Results

Abstract: Background Over 75% of the annual estimated 9.5 million deaths in India occur in the home, and the large majority of these do not have a certified cause. India and other developing countries urgently need reliable quantification of the causes of death. They also need better epidemiological evidence about the relevance of physical (such as blood pressure and obesity), behavioral (such as smoking, alcohol, HIV-1 risk taking, and immunization history), and biological (such as blood lipids and gene polymorphisms) measurements to the development of disease in individuals or disease rates in populations. We report here on the rationale, design, and implementation of the world's largest prospective study of the causes and correlates of mortality.

KAGRA: 2.5 Generation Interferometric Gravitational Wave Detector

Abstract: The recent detections of gravitational waves (GWs) reported by the LIGO and Virgo collaborations have made a significant impact on physics and astronomy. A global network of GW detectors will play a key role in uncovering the unknown nature of the sources in coordinated observations with astronomical telescopes and detectors. Here we introduce KAGRA, a new GW detector with two 3 km baseline arms arranged in an ‘L’ shape. KAGRA’s design is similar to the second generations of Advanced LIGO and Advanced Virgo, but it will be operating at cryogenic temperatures with sapphire mirrors. This low-temperature feature is advantageous for improving the sensitivity around 100 Hz and is considered to be an important feature for the third-generation GW detector concept (for example, the Einstein Telescope of Europe or the Cosmic Explorer of the United States). Hence, KAGRA is often called a 2.5-generation GW detector based on laser interferometry. KAGRA’s first observation run is scheduled in late 2019, aiming to join the third observation run of the advanced LIGO–Virgo network. When operating along with the existing GW detectors, KAGRA will be helpful in locating GW sources more accurately and determining the source parameters with higher precision, providing information for follow-up observations of GW trigger candidates.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

Fast parallel algorithms for short-range molecular dynamics

Abstract: Three parallel algorithms for classical molecular dynamics are presented. The first assigns each processor a fixed subset of atoms; the second assigns each a fixed subset of inter-atomic forces to compute; the third assigns each a fixed spatial region. The algorithms are suitable for molecular dynamics models which can be difficult to parallelize efficiently—those with short-range forces where the neighbors of each atom change rapidly. They can be implemented on any distributed-memory parallel machine which allows for message-passing of data between independently executing processors. The algorithms are tested on a standard Lennard-Jones benchmark problem for system sizes ranging from 500 to 100,000,000 atoms on several parallel supercomputers--the nCUBE 2, Intel iPSC/860 and Paragon, and Cray T3D. Comparing the results to the fastest reported vectorized Cray Y-MP and C90 algorithm shows that the current generation of parallel machines is competitive with conventional vector supercomputers even for small problems. For large problems, the spatial algorithm achieves parallel efficiencies of 90% and a 1840-node Intel Paragon performs up to 165 faster than a single Cray C9O processor. Trade-offs between the three algorithms and guidelines for adapting them to more complex molecular dynamics simulations are also discussed.

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

Abstract: Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States, and is projected to rank fifth in 2020 in burden of disease worldwide, according to a study published by the World Bank/World Health Organization. Yet, COPD remains relatively unknown or ignored by the public as well as public health and government officials. In 1998, in an effort to bring more attention to COPD, its management, and its prevention, a committed group of scientists encouraged the U.S. National Heart, Lung, and Blood Institute and the World Health Organization to form the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Among the important objectives of GOLD are to increase awareness of COPD and to help the millions of people who suffer from this disease and die prematurely of it or its complications. The first step in the GOLD program was to prepare a consensus report, Global Strategy for the Diagnosis, Management, and Prevention of COPD, published in 2001. The present, newly revised document follows the same format as the original consensus report, but has been updated to reflect the many publications on COPD that have appeared. GOLD national leaders, a network of international experts, have initiated investigations of the causes and prevalence of COPD in their countries, and developed innovative approaches for the dissemination and implementation of COPD management guidelines. We appreciate the enormous amount of work the GOLD national leaders have done on behalf of their patients with COPD. Despite the achievements in the 5 years since the GOLD report was originally published, considerable additional work is ahead of us if we are to control this major public health problem. The GOLD initiative will continue to bring COPD to the attention of governments, public health officials, health care workers, and the general public, but a concerted effort by all involved in health care will be necessary.

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